2024
DIANA - Detectability Investgations using Artificial Nodal Additions
Bayerlein R, Xia M, Xie H, Spencer B, Ouyang J, Fakhri G, Nardo L, Liu C, Badawi R. DIANA - Detectability Investgations using Artificial Nodal Additions. 2024, 00: 1-1. DOI: 10.1109/nss/mic/rtsd57108.2024.10657528.Peer-Reviewed Original ResearchContrast recovery coefficientContrast-to-noise ratioLesion-to-background ratioList-mode dataTotal-body PET/CT scannerPositron emission tomographyContrast recoveryOSEM algorithmPatient motionPET/CT scannerArtificial lesionsImage quality metricsLesion detectionQuantitative accuracyPositron emission tomography scanRecovery coefficientCount densityImage contrastBody mass indexImage noisePositron emission tomography imaging techniquesFrame lengthImage smoothingActivity concentrationsAccuracy of lesion detection
2011
Impact of Time-of-Flight PET on Whole-Body Oncologic Studies: A Human Observer Lesion Detection and Localization Study
Surti S, Scheuermann J, Fakhri G, Daube-Witherspoon M, Lim R, Abi-Hatem N, Moussallem E, Benard F, Mankoff D, Karp J. Impact of Time-of-Flight PET on Whole-Body Oncologic Studies: A Human Observer Lesion Detection and Localization Study. Journal Of Nuclear Medicine 2011, 52: 712-719. PMID: 21498523, PMCID: PMC3104282, DOI: 10.2967/jnumed.110.086678.Peer-Reviewed Original ResearchConceptsLocalization receiver operating characteristicsTime-of-flight PETLong scan timesArea under the LROC curveScan timeFunction of scan timePatient sizeTime-of-flight (TOFLROC curveLow-uptake lesionsTOF imagesTOF kernelLesion detection taskTOF-PETWhole-body oncologyLesion detection performanceScanner fieldPhantom studyPatient body mass indexProbability of correct localizationLesion detectionSphere dataBody mass indexLarger patientsReceiver operating characteristicImprovement in Lesion Detection with Whole-Body Oncologic Time-of-Flight PET
Fakhri G, Surti S, Trott C, Scheuermann J, Karp J. Improvement in Lesion Detection with Whole-Body Oncologic Time-of-Flight PET. Journal Of Nuclear Medicine 2011, 52: 347-353. PMID: 21321265, PMCID: PMC3088884, DOI: 10.2967/jnumed.110.080382.Peer-Reviewed Original ResearchConceptsTime-of-flight PETTime-of-flightTOF-PETTime-of-flight reconstructionBody mass indexList-mode dataNon-TOF PETObserver signal-to-noise ratioOrdered-subset expectation maximizationMass indexNon-TOFLesion detectionLesion detection performanceSpherical lesionsFunction of body mass indexSignal-to-noise ratioScan timePatient studiesLesion visibilityArtificial lesionsLiver lesionsPatientsLesionsLesion locationLow lesions
2009
Quantitative relationship between coronary calcium content and coronary flow reserve as assessed by integrated PET/CT imaging
Curillova Z, Yaman B, Dorbala S, Kwong R, Sitek A, El Fakhri G, Anagnostopoulos C, Di Carli M. Quantitative relationship between coronary calcium content and coronary flow reserve as assessed by integrated PET/CT imaging. European Journal Of Nuclear Medicine And Molecular Imaging 2009, 36: 1603-1610. PMID: 19387640, PMCID: PMC3117296, DOI: 10.1007/s00259-009-1121-1.Peer-Reviewed Original ResearchConceptsCoronary artery calcium scoreCoronary artery calciumCoronary vasodilator functionCoronary flow reserveCoronary artery diseaseHyperemic myocardial blood flowMyocardial blood flowVasodilator functionWeak inverse correlationCAC scoreCoronary artery calcium contentFlow reserveIncreasing CAC scorePer-vessel basisPer-patient basisInverse correlationBody mass indexCoronary calcium contentCoronary risk factorsCoronary vascular resistancePET/CT imagingConclusionIn patientsArtery calciumVascular resistanceMass index