2010
Bioanalytical inaccuracy: a threat to the integrity and efficiency of research
Young S, Anderson G. Bioanalytical inaccuracy: a threat to the integrity and efficiency of research. Journal Of Psychiatry And Neuroscience 2010, 35: 3-6. PMID: 20040241, PMCID: PMC2799499, DOI: 10.1503/jpn.090171.Peer-Reviewed Original Research
2000
Imaging extrastriatal dopamine D2 receptor occupancy by endogenous dopamine in healthy humans
Fujita M, Verhoeff N, Varrone A, Zoghbi S, Baldwin R, Jatlow P, Anderson G, Seibyl J, Innis R. Imaging extrastriatal dopamine D2 receptor occupancy by endogenous dopamine in healthy humans. European Journal Of Pharmacology 2000, 387: 179-188. PMID: 10650158, DOI: 10.1016/s0014-2999(99)00817-1.Peer-Reviewed Original ResearchConceptsAcute dopamine depletionDopamine depletionEndogenous dopamineAlpha-methylTemporal cortexExtrastriatal dopamine D2 receptor occupancyDopamine D2 receptor occupancyD2 receptor occupancySynaptic dopamine concentrationsSingle photon emissionNegative Symptom ScalePara-tyrosineExtrastriatal regionsOral administrationHealthy humansSymptom ScaleReceptor occupancyDopamine concentrationsDysphoric moodDopaminePhoton emissionHigh-affinity ligandsCortexVivo measurementsThalamus
1995
Linkage between brain serotonin concentration and the sex-specific part of the Y-chromosome in mice
Tordjman S, Roubertoux P, Carlier M, Moutier R, Anderson G, Launay M, Degrelle H. Linkage between brain serotonin concentration and the sex-specific part of the Y-chromosome in mice. Neuroscience Letters 1995, 183: 190-192. PMID: 7739791, DOI: 10.1016/0304-3940(94)11148-c.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain ChemistryFemaleMaleMiceMice, Inbred CBAMice, Inbred StrainsSerotoninSpecies SpecificityTestosteroneY Chromosome
1992
Brain Monoamines and Amino Acids in Gilles de la Tourette's Syndrome: A Preliminary Study of Subcortical Regions
Anderson G, Pollak E, CHATTERJEE D, Leckman J, Riddle M, Cohen D. Brain Monoamines and Amino Acids in Gilles de la Tourette's Syndrome: A Preliminary Study of Subcortical Regions. JAMA Psychiatry 1992, 49: 584-586. PMID: 1378261, DOI: 10.1001/archpsyc.1992.01820070078016.Peer-Reviewed Original ResearchConceptsGilles de la Tourette's syndromeLateral globus pallidusSubstantia nigra reticulataMedial globus pallidusLa Tourette's syndromeTourette syndromeGlobus pallidusSubthalamic nucleusSubcortical regionsTS groupMajor projection areaPossible pathophysiologic significanceLevels of monoaminesNeurotransmitter-related enzymesLow TS groupBrains of subjectsBrain monoaminesMonoamine metabolitesPathophysiologic significanceControl groupPostmortem tissueSyndromeBrainAvailable brainPallidus
1988
High-performance liquid chromatographic analysis of neurotransmitter amino acids in brain
Durkin T, Anderson G, Cohen D. High-performance liquid chromatographic analysis of neurotransmitter amino acids in brain. Journal Of Chromatography 1988, 428: 9-15. PMID: 2902104, DOI: 10.1016/s0378-4347(00)83885-2.Peer-Reviewed Original Research
1987
Serotonin in cisternal cerebrospinal fluid of the rat: Measurement and use as an index of functionally active serotonin
Anderson G, Teff K, Young S. Serotonin in cisternal cerebrospinal fluid of the rat: Measurement and use as an index of functionally active serotonin. Life Sciences 1987, 40: 2253-2260. PMID: 2438530, DOI: 10.1016/0024-3205(87)90061-0.Peer-Reviewed Original Research
1983
Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup
Shaywitz B, Teicher M, Cohen D, Anderson G, Young J, Levitt P. Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup. Psychopharmacology 1983, 82: 73-77. PMID: 6420833, DOI: 10.1007/bf00426384.Peer-Reviewed Original ResearchConceptsRat pupsDays of ageMotor activityBehavioral arousalPostsynaptic dopaminergic mechanismsReduction of norepinephrineReduction of dopamineGeneral motor activityMesolimbic dopaminergic pathwayDopaminergic mechanismsBrain dopaminePreferential reductionEscape latencyNoradrenergic mediationNorepinephrinePostnatal lifeWeek 3PupsSuch treatmentDopamineT-mazeShuttle boxAgeDesmethylimipraminePerformance deficitsDifferential effects of selective dopamine, norepinephrine or catecholamine depletion on activity and learning in the developing rat
Raskin L, Shaywitz B, Anderson G, Cohen D, Teicher M, Linakis J. Differential effects of selective dopamine, norepinephrine or catecholamine depletion on activity and learning in the developing rat. Pharmacology Biochemistry And Behavior 1983, 19: 743-749. PMID: 6647508, DOI: 10.1016/0091-3057(83)90073-4.Peer-Reviewed Original ResearchConceptsDays of ageT-mazeCentral catecholamine systemsSelective dopamine depletionSelective norepinephrine depletionDopamine depletionNE levelsNorepinephrine depletionCatecholamine depletionSevere learning impairmentIntraperitoneal injectionCatecholamine systemsSelective lesionsDay 28Selective dopamineNeonatal depletionLearning impairmentSelective depletionCatecholaminesClinical researchBehavioral effectsDeficit disorderShuttlebox performanceActivity levelsConstellation of behaviors
1982
Environmental and biologic interactions on behavior: Effects of artificial rearing in rat pups treated with 6‐hydroxydopamine
Goldenring J, Shaywitz B, Wool R, Batter D, Anderson G, Cohen D. Environmental and biologic interactions on behavior: Effects of artificial rearing in rat pups treated with 6‐hydroxydopamine. Developmental Psychobiology 1982, 15: 297-307. PMID: 6809512, DOI: 10.1002/dev.420150403.Peer-Reviewed Original ResearchClinical neurochemistry of autism and associated disorders
Young J, Kavanagh M, Anderson G, Shaywitz B, Cohen D. Clinical neurochemistry of autism and associated disorders. Journal Of Autism And Developmental Disorders 1982, 12: 147-165. PMID: 6184361, DOI: 10.1007/bf01531305.Peer-Reviewed Original ResearchConceptsNorepinephrine metabolismNeurochemical methodsClinical neurochemistryClinical studiesNeurochemical studiesBehavioral deficitsBiochemical dysfunctionBrain functionAutistic syndromeInfantile autismLow levelsNew studiesAutismDysfunctionSerotoninSyndromeAutistic individualsSymptomsNeurochemistryBrainMajor obstacle
1981
Determination of indoles and catechols in rat brain and pineal using liquid chromatography with fluorometric and amperometric detection
Anderson G, Young J, Batter D, Young S, Cohen D, Shaywitz B. Determination of indoles and catechols in rat brain and pineal using liquid chromatography with fluorometric and amperometric detection. Journal Of Chromatography 1981, 223: 315-320. PMID: 7251785, DOI: 10.1016/s0378-4347(00)80103-6.Peer-Reviewed Original ResearchApplications of liquid chromatographic-fluorometric systems in neurochemistry
Anderson G, Young J. Applications of liquid chromatographic-fluorometric systems in neurochemistry. Life Sciences 1981, 28: 507-517. PMID: 7010039, DOI: 10.1016/0024-3205(81)90144-2.Peer-Reviewed Original Research
1980
Simplified liquid chromatographic—electrochemical determination of norepinephrine and dopamine in rat brain
Anderson G, Batter D, Young J, Shaywitz B, Cohen D. Simplified liquid chromatographic—electrochemical determination of norepinephrine and dopamine in rat brain. Journal Of Chromatography 1980, 181: 453-455. PMID: 7391159, DOI: 10.1016/s0378-4347(00)81148-2.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain ChemistryCentrifugationChromatography, LiquidDopamineElectrochemistryNorepinephrineRatsSonication