Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder
Tordjman S, Anderson GM, Pichard N, Charbuy H, Touitou Y. Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. Biological Psychiatry 2005, 57: 134-138. PMID: 15652871, DOI: 10.1016/j.biopsych.2004.11.003.Peer-Reviewed Original ResearchConceptsAutistic disorderNocturnal urinary excretionPineal gland hormoneLow melatonin productionNormal control individualsMelatonin physiologyGroup of childrenUrinary excretionMelatonin administrationTanner stageSleep problemsNormal controlsReported alterationNocturnal excretionControl individualsExcretion rateDisordersGland hormoneMelatoninMelatonin productionAutistic impairmentsExcretionCircadian rhythmBehavioral expressionVerbal communication