2021
Improved outcomes and staging in non-small-cell lung cancer guided by a molecular assay
Gupta AR, Woodard GA, Jablons DM, Mann MJ, Kratz JR. Improved outcomes and staging in non-small-cell lung cancer guided by a molecular assay. Future Oncology 2021, 17: 4785-4795. PMID: 34435876, PMCID: PMC9039775, DOI: 10.2217/fon-2021-0517.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorCarcinogenesisCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantClinical Decision-MakingDatasets as TopicDisease-Free SurvivalGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLung NeoplasmsMolecular Diagnostic TechniquesNeoplasm Recurrence, LocalNeoplasm StagingPneumonectomyProspective StudiesReal-Time Polymerase Chain ReactionRisk AssessmentConceptsCell lung cancerUndetectable metastasesLung cancerCell lung cancer patientsDisease-free survivalAdjuvant chemotherapy decisionsTime of surgeryLung cancer patientsSurgical resectionComplete resectionProspective studyCancer patientsChemotherapy decisionsResectionMolecular assaysPatientsPredictive benefitMetastasisCancerMortalityQuantitative PCRExpression profilesEarly stagesAssaysSurgeryMolecular Risk Stratification is Independent of EGFR Mutation Status in Identifying Early-Stage Non–Squamous Non–Small Cell Lung Cancer Patients at Risk for Recurrence and Likely to Benefit From Adjuvant Chemotherapy
Woodard GA, Kratz JR, Haro G, Gubens MA, Blakely CM, Jones KD, Mann MJ, Jablons DM. Molecular Risk Stratification is Independent of EGFR Mutation Status in Identifying Early-Stage Non–Squamous Non–Small Cell Lung Cancer Patients at Risk for Recurrence and Likely to Benefit From Adjuvant Chemotherapy. Clinical Lung Cancer 2021, 22: 587-595. PMID: 34544620, DOI: 10.1016/j.cllc.2021.08.008.Peer-Reviewed Original ResearchConceptsMolecular risk stratificationAdjuvant chemotherapyDisease-free survivalEGFR mutation statusAdjuvant interventionRisk stratificationEGFR patientsNSCLC patientsEGFR statusMutation statusSmall cell lung cancer patientsNon-squamous NSCLC patientsCell lung cancer patientsStage IA NSCLCStage IB patientsThird-generation TKIsEarly-stage NSCLCNon-Squamous NonLung cancer patientsEarly-stage cohortIB patientsProspective studyResidual diseaseCancer patientsEGFR mutationsResectability, Recurrence, and Risk Stratification of Giant Solitary Fibrous Tumors in the Thoracic Cavity
Woodard GA, Fels Elliott DR, Yap A, Haro GJ, Kratz JR, Mann MJ, Jones KD, Jablons DM. Resectability, Recurrence, and Risk Stratification of Giant Solitary Fibrous Tumors in the Thoracic Cavity. Annals Of Surgical Oncology 2021, 28: 4953-4959. PMID: 33728541, DOI: 10.1245/s10434-021-09757-7.Peer-Reviewed Original ResearchMeSH KeywordsHumansNeoplasm Recurrence, LocalRisk AssessmentRisk FactorsSolitary Fibrous TumorsThoracic CavityConceptsSingle-institution reviewInstitution reviewFibrous tumorThoracic cavityLong-term survival dataGiant solitary fibrous tumorBackgroundSolitary fibrous tumorsKaplan-Meier analysisPredictors of recurrenceRare mesenchymal tumorLong-term outcomesRisk of recurrenceMajority of tumorsSolitary fibrous tumorLong-term survivalSFT recurrencePathologic characteristicsRisk stratificationTumor sizeMesenchymal tumorsRisk factorsTumor necrosisVisceral pleuraClinical informationRecurrence
2009
Probiotics Improve Outcomes After Roux-en-Y Gastric Bypass Surgery: A Prospective Randomized Trial
Woodard GA, Encarnacion B, Downey JR, Peraza J, Chong K, Hernandez-Boussard T, Morton JM. Probiotics Improve Outcomes After Roux-en-Y Gastric Bypass Surgery: A Prospective Randomized Trial. Journal Of Gastrointestinal Surgery 2009, 13: 1198-1204. PMID: 19381735, DOI: 10.1007/s11605-009-0891-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBody Mass IndexConfidence IntervalsDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesGastric BypassHumansMaleMiddle AgedObesity, MorbidPatient SatisfactionPostoperative CarePostoperative ComplicationsProbabilityProbioticsProspective StudiesReference ValuesRisk AssessmentTreatment OutcomeWeight LossConceptsGastric bypass surgeryBacterial overgrowthProbiotic groupControl groupWeight lossBypass surgeryGreater percent excess weight lossPercent excess weight lossY Gastric Bypass SurgeryExcess weight lossProspective randomized trialsVitamin B12 levelsMethodsForty-four patientsQuality of lifeEnduring treatmentGastric bypassMorbid obesityB12 levelsPostoperative changesResultsAt 6Randomized trialsVitamin B12 availabilityProbiotic administrationGastrointestinal floraGI microbiota