Kv1.3 potassium channel blockade as an approach to insulin resistance
Desir GV. Kv1.3 potassium channel blockade as an approach to insulin resistance. Expert Opinion On Therapeutic Targets 2005, 9: 571-579. PMID: 15948674, DOI: 10.1517/14728222.9.3.571.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiabetes MellitusGlucoseHumansHypoglycemic AgentsInsulin ResistanceKv1.3 Potassium ChannelConceptsInsulin resistanceInsulin sensitivityKv1.3 channel inhibitionPotassium channel blockadePeripheral insulin sensitivityPotential therapeutic targetDevastating metabolic diseaseType II diabetesVoltage-gated potassium channelsAbnormal glucoseDiabetes mellitusInsulin deficiencyDevelopment of drugsInflammatory cytokinesChannel blockadeGlucose metabolismTherapeutic targetCardinal featuresMetabolic diseasesChannel inhibitionII diabetesLipid metabolismHealthcare expendituresPotassium channelsPromising target