2005
Molecular Diversity and Regulation of Renal Potassium Channels
Hebert SC, Desir G, Giebisch G, Wang W. Molecular Diversity and Regulation of Renal Potassium Channels. Physiological Reviews 2005, 85: 319-371. PMID: 15618483, PMCID: PMC2838721, DOI: 10.1152/physrev.00051.2003.Peer-Reviewed Original ResearchConceptsRenal potassium channelsAnimal cellsCell movementDistinct functionsMolecular diversitySuccessful cloningRenal tubule epithelial cellsExcitable cellsSingle-channel analysisBiophysical propertiesMembrane potentialTubule epithelial cellsEpithelial cellsPotassium channelsRegulationCell volumeCellsImportant roleCloningTubule cellsPlantsDiversitySignificant progressFunction
1993
Identification of a novel K-channel gene (KC22) that is highly expressed in distal tubule of rabbit kidney
Desir GV, Velazquez H. Identification of a novel K-channel gene (KC22) that is highly expressed in distal tubule of rabbit kidney. American Journal Of Physiology 1993, 264: f128-f133. PMID: 7679255, DOI: 10.1152/ajprenal.1993.264.1.f128.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionRabbit kidneyKidney cortexWhole kidney cortexShaker gene familyDistal tubule cellsVoltage-gated K channelsRenal tissueDistal tubulesTubule cellsRibonuclease protectionPrimary culturesKidneyChain reactionExpression levelsK channelsCortexTubulesPartial-length sequencesAbundant isoformIsoformsKidney cDNAK channel genes