2023
Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17
Heimer R, Black A, Lin H, Grau L, Fiellin D, Howell B, Hawk K, D'Onofrio G, Becker W. Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17. Drug And Alcohol Dependence 2023, 254: 111040. PMID: 38043226, PMCID: PMC10872282, DOI: 10.1016/j.drugalcdep.2023.111040.Peer-Reviewed Original ResearchConceptsNon-medication treatmentsRelative riskOpioid overdose deathsIncidence rateMOUD treatmentOverdose deathsOpioid use disorder treatmentResults Incidence ratesRetrospective cohort studyDifferent treatment modalitiesPopulation-level effortsUse disorder treatmentFatal opioid poisoningsCohort studyOpioid poisoningTreatment modalitiesConclusion ExposurePoisoning deathsFatal overdosesTreatment exposureDisorder treatmentDeathTreatmentMethadoneRiskModeling human health behavior with a new index that measures connectivity
Bernstein S, Li F, Abujarad F, Grant D, D'Onofrio G, Dziura J. Modeling human health behavior with a new index that measures connectivity. Preventive Medicine Reports 2023, 33: 102172. PMID: 37223571, PMCID: PMC10201843, DOI: 10.1016/j.pmedr.2023.102172.Peer-Reviewed Original ResearchHealth behaviorsTrial of treatmentHospital emergency departmentUrban hospital emergency departmentAlcohol use disorderCritical health behaviorsEffects of interventionsPrimary endpointSubstance use interventionsMedication adherenceEmergency departmentOriginal trialBinge drinkingUse disordersHealthy behaviorsStudy designHuman health behaviourTrialsInterventionUse interventionsMonthly bingeAdherenceTreatmentDrinkingReal-time interventions
2022
Trends and Disparities in Access to Buprenorphine Treatment Following an Opioid-Related Emergency Department Visit Among an Insured Cohort, 2014-2020
Stevens MA, Tsai J, Savitz ST, Nath B, Melnick ER, D’Onofrio G, Jeffery MM. Trends and Disparities in Access to Buprenorphine Treatment Following an Opioid-Related Emergency Department Visit Among an Insured Cohort, 2014-2020. JAMA Network Open 2022, 5: e2215287. PMID: 35657629, PMCID: PMC9166266, DOI: 10.1001/jamanetworkopen.2022.15287.Peer-Reviewed Original Research
2021
Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study
McCormack RP, Rotrosen J, Gauthier P, D’Onofrio G, Fiellin DA, Marsch LA, Novo P, Liu D, Edelman EJ, Farkas S, Matthews AG, Mulatya C, Salazar D, Wolff J, Knight R, Goodman W, Hawk K. Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study. Addiction Science & Clinical Practice 2021, 16: 16. PMID: 33750454, PMCID: PMC7941881, DOI: 10.1186/s13722-021-00224-y.Peer-Reviewed Original ResearchConceptsEmergency departmentLow-resource settingsImplementation facilitationUse disordersEmergency department-initiated buprenorphineResource settingsImplementation-effectiveness studyTreatment of OUDOpioid use disorderNon-emergent conditionsSubstance use disordersImplementation feasibility studyOUD interventionsED settingMedical recordsBuprenorphineClinical protocolsHigh needReferral programDisorder screeningDiscussionThis studyImplementation studyAdministrative dataReferralTreatmentMerging statewide data in a public/university collaboration to address opioid use disorder and overdose
Becker WC, Heimer R, Dormitzer CM, Doernberg M, D’Onofrio G, Grau LE, Hawk K, Lin HJ, Secora AM, Fiellin DA. Merging statewide data in a public/university collaboration to address opioid use disorder and overdose. Addiction Science & Clinical Practice 2021, 16: 1. PMID: 33397480, PMCID: PMC7780404, DOI: 10.1186/s13722-020-00211-9.Peer-Reviewed Original Research