2024
"SafetyNet": Evaluation of a Recovery Coach and Paramedic Intervention Following Naloxone Resuscitation From an Opioid Overdose.
Joseph D, Brokowski C, D'Onofrio G, Bogucki S, McGovern J, Allen R, Dziura J, Cone D, Pantalon M. "SafetyNet": Evaluation of a Recovery Coach and Paramedic Intervention Following Naloxone Resuscitation From an Opioid Overdose. Substance Use & Addiction Journal 2024, 29767342241266412. PMID: 39171791, DOI: 10.1177/29767342241266412.Peer-Reviewed Original ResearchOverdose eventsRecovery coachesOpioid overdoseFollow-up encountersReducing illicit drug useFifty-five participantsIllicit drug useParamedic interventionsTrained paramedicsPeer recoveryFollow-upHealth educationOpioid use disorderSample size estimationParamedicsOpioid-positive urine testsPositive urine toxicology screenMOUD engagementMedical concernsMOUDUrine toxicology screenDrug useParticipantsPositive urine testIntervention
2023
Modeling human health behavior with a new index that measures connectivity
Bernstein S, Li F, Abujarad F, Grant D, D'Onofrio G, Dziura J. Modeling human health behavior with a new index that measures connectivity. Preventive Medicine Reports 2023, 33: 102172. PMID: 37223571, PMCID: PMC10201843, DOI: 10.1016/j.pmedr.2023.102172.Peer-Reviewed Original ResearchHealth behaviorsTrial of treatmentHospital emergency departmentUrban hospital emergency departmentAlcohol use disorderCritical health behaviorsEffects of interventionsPrimary endpointSubstance use interventionsMedication adherenceEmergency departmentOriginal trialBinge drinkingUse disordersHealthy behaviorsStudy designHuman health behaviourTrialsInterventionUse interventionsMonthly bingeAdherenceTreatmentDrinkingReal-time interventionsReal-World Observational Evaluation of Common Interventions to Reduce Emergency Department Prescribing of Opioid Medications
Sangal R, Rothenberg C, Hawk K, D'Onofrio G, Hsiao A, Solad Y, Venkatesh A. Real-World Observational Evaluation of Common Interventions to Reduce Emergency Department Prescribing of Opioid Medications. The Joint Commission Journal On Quality And Patient Safety 2023, 49: 239-246. PMID: 36914528, DOI: 10.1016/j.jcjq.2023.01.013.Peer-Reviewed Original ResearchConceptsOpioid prescribingED visitsElectronic health recordsOpioid prescriptionsEmergency department opioid prescriptionsAnalgesia prescriptionOpioid stewardshipOpioid medicationsSecondary outcomesPrimary outcomePreintervention periodInterruptive alertsCommon interventionPrescribingAlert fatigueElectronic prescribingPrevious interventionsHospital systemObservational evaluationHealth recordsVisitsStewardship policiesInterventionOutcomesPrescription
2022
Assessing the impact of the Good Samaritan Law in the state of Connecticut: a system dynamics approach
Sabounchi NS, Heckmann R, D’Onofrio G, Walker J, Heimer R. Assessing the impact of the Good Samaritan Law in the state of Connecticut: a system dynamics approach. Health Research Policy And Systems 2022, 20: 5. PMID: 34991591, PMCID: PMC8734429, DOI: 10.1186/s12961-021-00807-w.Peer-Reviewed Original ResearchConceptsOpioid use disorderOverdose deathsGood Samaritan lawsEmergency department visitsOpioid-related deathsPublic health interventionsBehavioral changesPublic health officialsED visitsDepartment visitsOpioid usersUse disordersHealth outcomesOpioid crisisHealth interventionsHealth officialsDeathOverdoseVisitsInterventionOutcomesState of ConnecticutMultiple strategies
2021
Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies
Tuzzio L, Meyers CM, Dember LM, Grudzen CR, Melnick ER, Staman KL, Huang SS, Richards J, DeBar L, Vazquez MA, Green BB, Coronado GD, Jarvik JG, Braciszewski J, Ho PM, Wells BL, James K, Toto R, D’Onofrio G, Volandes A, Kuklinski MR, Catalano RF, Sterling SA, Morse EF, Curtis L, Larson EB. Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthcare 2021, 8: 100432. PMID: 34175091, PMCID: PMC8900087, DOI: 10.1016/j.hjdsi.2020.100432.Peer-Reviewed Original ResearchConceptsPragmatic clinical trialsQI initiativesHealthcare systemClinical trialsHigh-quality patient-centered careClinical practice guidelinesHigh-quality evidencePatient-centered careQuality of careQuality improvement activitiesPractice guidelinesRoutine collaborationHealth questionsHealth systemTrialsHealth system operationsConduct phaseCareStudy teamPublic healthInterventionImprovement activitiesEPCTs
2018
Emergency department screening and interventions for substance use disorders
Hawk K, D’Onofrio G. Emergency department screening and interventions for substance use disorders. Addiction Science & Clinical Practice 2018, 13: 18. PMID: 30078375, PMCID: PMC6077851, DOI: 10.1186/s13722-018-0117-1.Peer-Reviewed Original Research
2017
Cost‐effectiveness of emergency department‐initiated treatment for opioid dependence
Busch SH, Fiellin DA, Chawarski MC, Owens PH, Pantalon MV, Hawk K, Bernstein SL, O'Connor PG, D'Onofrio G. Cost‐effectiveness of emergency department‐initiated treatment for opioid dependence. Addiction 2017, 112: 2002-2010. PMID: 28815789, PMCID: PMC5657503, DOI: 10.1111/add.13900.Peer-Reviewed Original ResearchConceptsCost-effectiveness acceptability curvesOpioid dependenceCommunity-based treatmentBrief interventionAcceptability curvesPast weekHealth care system costsHealth care system perspectiveAddiction treatmentOpioid-dependent patientsPatient time costsHealth care useFormal addiction treatmentBuprenorphine treatmentUrban EDEmergency departmentPrimary carePatient engagementTreatment engagementPatientsReferralSecondary analysisBuprenorphineNumber of daysIntervention
2007
Public health considerations in knowledge translation in the emergency department.
Bernstein S, Bernstein E, Boudreaux E, Babcock-Irvin C, Mello M, Kapur A, Becker B, Sattin R, Cohen V, D'Onofrio G. Public health considerations in knowledge translation in the emergency department. Academic Emergency Medicine 2007, 14: 1036-41. PMID: 17699805, DOI: 10.1197/j.aem.2007.06.012.Peer-Reviewed Original ResearchConceptsPublic health interventionsEmergency departmentHealth interventionsLack of efficacyPublic health initiativesKnowledge translationPublic health expertsPublic health considerationsED settingPreventive careCurrent evidenceConsensus conferenceClinical information systemsED personnelEffective preventivePreventive interventionsHealth initiativesMedical careEvidence uptakeVulnerable populationsHealth expertsUnique populationEmergency medicineInterventionHealth considerations
2006
Alcohol-related problems: Emergency physicians’ current practice and attitudes
O’Rourke M, Richardson LD, Wilets I, D’Onofrio G. Alcohol-related problems: Emergency physicians’ current practice and attitudes. Journal Of Emergency Medicine 2006, 30: 263-268. PMID: 16677975, DOI: 10.1016/j.jemermed.2005.05.031.Peer-Reviewed Original Research
2002
Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review.
D'Onofrio G, Degutis L. Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review. Academic Emergency Medicine 2002, 9: 627-38. PMID: 12045080, DOI: 10.1111/j.1553-2712.2002.tb02304.x.Peer-Reviewed Original ResearchConceptsEmergency departmentU.S. Preventive Services Task Force reportAlcohol-related problemsSystematic reviewMethodology of systematic reviewsMethodological scoring systemPrevention of mortalityPrimary outcome measureBrief interventionPreventive careIncreased referralsED-basedOutcome measuresTask Force ReportExplanatory pieceTeam membersCochrane LibraryPrimary articlesAlcohol problemsStudy populationClinical practiceDecreased consumptionInterventionCollege settingPublished criteria
1998
Patients with Alcohol Problems in the Emergency Department, Part 2: Intervention and Referral
D'Onofrio G, Bernstein E, Bernstein J, Woolard R, Brewer P, Craig S, Zink B, Force F. Patients with Alcohol Problems in the Emergency Department, Part 2: Intervention and Referral. Academic Emergency Medicine 1998, 5: 1210-1217. PMID: 9864135, DOI: 10.1111/j.1553-2712.1998.tb02697.x.Peer-Reviewed Original Research