2022
Natural history of bicuspid aortic valves and ascending aortic aneurysms: Aortic center experience
Bellaire CP, Tharakan SM, Roy J, Puskas JD, Di Luozzo G. Natural history of bicuspid aortic valves and ascending aortic aneurysms: Aortic center experience. Journal Of Cardiac Surgery 2022, 37: 2326-2335. PMID: 35535018, DOI: 10.1111/jocs.16597.Peer-Reviewed Original ResearchConceptsBicuspid aortic valveAdverse event ratesTAV patientsEntire cohortAortic aneurysmAortic valveComputerized tomographyLow adverse event ratesOverall adverse event rateNatural historyEvent ratesTricuspid aortic valve patientsValve typeRoutine computerized tomographyMore CT scansAortic valve patientsCoronary artery diseaseMean aneurysm sizeAneurysm growth rateAortic valve typeSimilar natural historyAortic eventsConservative managementSmoking historyUnmatched cohort
2013
A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms
Geisbüsch S, Stefanovic A, Schray D, Oyfe I, Lin HM, Di Luozzo G, Griepp RB. A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 68-74. PMID: 23953716, DOI: 10.1016/j.jtcvs.2013.06.030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsAortaAortic AneurysmAortic RuptureAortographyCase-Control StudiesChi-Square DistributionDisease ProgressionFemaleFibrinolytic AgentsHumansLeast-Squares AnalysisLinear ModelsMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsTime FactorsTomography, X-Ray ComputedVascular Surgical ProceduresConceptsTotal aortic volumeAscending Aortic AneurysmAortic aneurysmAortic volumeModerate size aneurysmsReference groupML/yearAntithrombotic medicationAortic pathologySurgical indicationsUnderwent operationAortic sizeProspective studyEmergency departmentAortic growthSurveillance groupLarge aneurysmsRisk factorsSinotubular junctionTomography scanTomography volume measurementsDissection riskPatientsCompelling indicationsAneurysms
2007
Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow?
Etz CD, Homann T, Silovitz D, Bodian CA, Luehr M, Di Luozzo G, Plestis KA, Griepp RB. Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow? The Annals Of Thoracic Surgery 2007, 84: 1206-1213. PMID: 17888971, DOI: 10.1016/j.athoracsur.2007.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortaAorta, ThoracicAortic DiseasesBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationChildCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPolyethylene TerephthalatesProbabilityProsthesis DesignProsthesis FailureReoperationRetrospective StudiesRisk AssessmentSurvival RateTreatment OutcomeConceptsDacron graftThoracic aortaGraft expansionPostoperative computed tomography scansAortic valve-sparing proceduresDevelopment of regurgitationDiseased aortic segmentMedian graft diameterRoutine postoperative surveillanceType III endoleakValve-sparing proceduresComputed tomography scanEntire thoracic aortaComputed tomography studyDacron vascular graftsVascular Dacron graftsVascular graft replacementAorta graftThoracoabdominal aneurysmsEndoluminal repairGraft replacementPostoperative surveillanceDescending AortaGraft diameterAortic segments
2000
Vascular smooth muscle cell effect on endothelial cell endothelin-1 production
Di Luozzo G, Bhargava J, Powell R. Vascular smooth muscle cell effect on endothelial cell endothelin-1 production. Journal Of Vascular Surgery 2000, 31: 781-789. PMID: 10753286, DOI: 10.1067/mva.2000.103788.Peer-Reviewed Original ResearchConceptsSmooth muscle cellsET-1 productionEndothelin-1SMC proliferationEndothelial cellsNitro-L-arginine methyl esterNitric oxide synthase activityEC stimulationEndothelin-1 productionVascular lesion developmentNO synthase inhibitorOxide synthase activityEffects of SMCEts-1 proteinReceptor blockersCo-culture modelSMC inhibitionSynthase inhibitorLesion developmentB receptorMuscle cellsPotent mitogenRNA levelsProtein levelsPutative factors