2019
SS24. Short-Term Outcomes of Open Thoracoabdominal Aortic Aneurysm Repairs: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database
Mohebali J, Patel V, Di Luozzo G, Yerokun B, Xian Y, Thibault D, Shahian D, MacGillivray T. SS24. Short-Term Outcomes of Open Thoracoabdominal Aortic Aneurysm Repairs: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database. Journal Of Vascular Surgery 2019, 69: e201. DOI: 10.1016/j.jvs.2019.04.288.Peer-Reviewed Original ResearchParaspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways
Lewis ER, Geisbüsch S, Chang YJ, Costa V, Husain S, Soteropoulos P, Griepp RB, Di Luozzo G. Paraspinous muscle gene expression profiling following simulated staged endovascular repair of thoracoabdominal aortic aneurysm: exploring potential therapeutic pathways. European Journal Of Cardio-Thoracic Surgery 2019, 57: 30-38. PMID: 31006003, DOI: 10.1093/ejcts/ezz113.Peer-Reviewed Original ResearchConceptsAneurysm repairGene expression profilingCollateral networkThoracoabdominal aortic aneurysm repairSpinal collateral networkSpinal segmental arteriesSuch extensive proceduresThoracoabdominal aortic aneurysmsAortic aneurysm repairSpinal cord perfusionSpinal cord injuryPotential therapeutic pathwayExpression profilingArteriolar remodellingTAAA repairCord perfusionNeurological complicationsEndovascular repairNeuroprotective effectsEndovascular techniquesCord injuryAortic aneurysmCoil embolizationEndovascular coilingEndovascular intervention
2013
Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model
Geisbüsch S, Stefanovic A, Koruth JS, Lin HM, Morgello S, Weisz DJ, Griepp RB, Di Luozzo G. Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: An experimental model. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 220-227. PMID: 24220154, PMCID: PMC3918675, DOI: 10.1016/j.jtcvs.2013.09.022.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationEmbolization, TherapeuticEndovascular ProceduresHindlimbLumbosacral RegionModels, AnimalMuscle, SkeletalParaplegiaRecovery of FunctionRegional Blood FlowSpinal Cord IschemiaSwineThoracic ArteriesTime FactorsVideo RecordingConceptsSpinal cord injuryThoracoabdominal aneurysm repairHind limb functionSegmental arteriesTAAA repairAneurysm repairCord injuryGroup 2Tarlov scoreLimb functionCoil embolizationExperimental modelSpinal cordGroup 1Ischemic spinal cord injuryPostoperative spinal cord injuryHybrid TAAA repairJuvenile Yorkshire pigsLumbar segmental arteriesModified Tarlov scoreEndovascular coil embolizationLower thoracic/upper lumbar regionUpper lumbar regionPrevents paraplegiaHistopathologic injury
2012
Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update
Di Luozzo G. Visceral and spinal cord protection during thoracoabdominal aortic aneurysm repair: Clinical and laboratory update. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: s135-s138. PMID: 23260453, DOI: 10.1016/j.jtcvs.2012.11.053.Peer-Reviewed Original ResearchImaging of vascular remodeling after simulated thoracoabdominal aneurysm repair
Geisbüsch S, Schray D, Bischoff MS, Lin HM, Griepp RB, Di Luozzo G. Imaging of vascular remodeling after simulated thoracoabdominal aneurysm repair. Journal Of Thoracic And Cardiovascular Surgery 2012, 144: 1471-1478. PMID: 23010582, PMCID: PMC3496032, DOI: 10.1016/j.jtcvs.2012.08.062.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicArteriesBarium SulfateBehavior, AnimalCollateral CirculationContrast MediaDilatation, PathologicDisease Models, AnimalFemaleLatexLigationMammary ArteriesMultidetector Computed TomographyNeovascularization, PhysiologicParaplegiaReplica TechniquesSpinal CordSpinal Cord IschemiaSwineTime FactorsVascular Surgical ProceduresConceptsAnterior spinal arterySpinal cord blood supplySmall collateral vesselsAneurysm repairCollateral vesselsBlood supplyJuvenile Yorkshire pigsRisk of paraplegiaThoracoabdominal aneurysm repairThoracoabdominal aortic aneurysmsSpinal cord circulationEndovascular repairSpinal arteryArtery sacrificeIntercostal arteriesCord circulationInternal thoracicAortic aneurysmTomographic scanTomographic scanningVascular remodelingGroup 2Group 1Group 3Previous interventionsQuality of life and survival of septuagenarians and octogenarians after repair of descending and thoracoabdominal aortic aneurysms
Di Luozzo G, Shirali AS, Varghese R, Lin HM, Weiss AJ, Bischoff MS, Griepp RB. Quality of life and survival of septuagenarians and octogenarians after repair of descending and thoracoabdominal aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: 378-384. PMID: 22365063, DOI: 10.1016/j.jtcvs.2012.01.068.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Aneurysm, ThoracicFemaleHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleOdds RatioProportional Hazards ModelsQuality of LifeRespiratory Distress SyndromeRetrospective StudiesRisk AssessmentRisk FactorsSex FactorsSurveys and QuestionnairesTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsQuality of lifeBody mass indexGender-matched populationLong-term survivalHospital mortalityMass indexThoracoabdominal aortic aneurysm repairAcute respiratory distress syndromeHigher body mass indexComplex aortic operationsOne-year survivalThoracoabdominal aortic aneurysmsAortic aneurysm repairItem Health SurveyRespiratory distress syndromeLower vitality scoresTAAA repairAortic operationsElderly patientsAneurysm repairDistress syndromePostoperative qualityRetrospective reviewThoracic aneurysmLife scores
2011
A propensity score–matched comparison of deep versus mild hypothermia during thoracoabdominal aortic surgery
Weiss AJ, Lin HM, Bischoff MS, Scheumann J, Lazala R, Griepp RB, Di Luozzo G. A propensity score–matched comparison of deep versus mild hypothermia during thoracoabdominal aortic surgery. Journal Of Thoracic And Cardiovascular Surgery 2011, 143: 186-193. PMID: 21885069, DOI: 10.1016/j.jtcvs.2011.07.020.Peer-Reviewed Original ResearchConceptsPermanent adverse outcomesThoracoabdominal aortic aneurysm repairDeep hypothermic circulatory arrestAortic aneurysm repairHypothermic circulatory arrestAdverse outcomesHypothermic circulatory arrest groupCirculatory arrest groupRenal failureLiver failureAneurysm repairCirculatory arrestArrest groupHypothermic circulatory arrest techniqueThoracoabdominal aortic aneurysm operationsPropensity score-matched analysisPropensity score-matched comparisonAortic aneurysm operationsPropensity-matched studySignificant decreased oddsThirty-day mortalityThoracoabdominal aortic surgeryAcute renal failureAdverse outcome ratesElephant trunk procedureStaged Approach Prevents Spinal Cord Injury in Hybrid Surgical-Endovascular Thoracoabdominal Aortic Aneurysm Repair: An Experimental Model
Bischoff MS, Scheumann J, Brenner RM, Ladage D, Bodian CA, Kleinman G, Ellozy SH, Di Luozzo G, Etz CD, Griepp RB. Staged Approach Prevents Spinal Cord Injury in Hybrid Surgical-Endovascular Thoracoabdominal Aortic Aneurysm Repair: An Experimental Model. The Annals Of Thoracic Surgery 2011, 92: 138-146. PMID: 21718839, DOI: 10.1016/j.athoracsur.2011.03.098.Peer-Reviewed Original ResearchMeSH KeywordsAngiographyAngioplastyAnimalsAortic Aneurysm, ThoracicCombined Modality TherapyDisease Models, AnimalFemaleFollow-Up StudiesIntraoperative ComplicationsMonitoring, IntraoperativeRandom AllocationRisk AssessmentSpinal CordSpinal Cord InjuriesStentsSurvival RateSwineTreatment OutcomeVascular Surgical ProceduresConceptsGroup 1Group 2Thoracoabdominal aortic aneurysm repairJuvenile Yorkshire pigsSevere ischemic damageHind limb functionAortic aneurysm repairStent graft occlusionLumbar spinal cordModified Tarlov scoreSpinal cord injuryEndovascular coverageTarlov scoreGraft occlusionAneurysm repairArtery ligationIntercostal arteriesIschemic damageCord injuryLimb functionSudden occlusionSpinal cordLower thoracicHistopathologic analysisPorcine modelSpinal Cord Preservation in Thoracoabdominal Aneurysm Repair
Bischoff MS, Di Luozzo G, Griepp EB, Griepp RB. Spinal Cord Preservation in Thoracoabdominal Aneurysm Repair. Perspectives In Vascular Surgery And Endovascular Therapy 2011, 23: 214-222. PMID: 21502113, DOI: 10.1177/1531003511400622.Peer-Reviewed Original ResearchConceptsSpinal cord injuryThoracoabdominal aneurysm repairAneurysm repairIncidence of paraplegiaSpinal cord preservationSpinal cord protectionEndovascular aortic repairOpen surgical repairSpinal cord vasculatureAortic repairEndovascular approachSurgical repairDreadful complicationCord injuryEndovascular proceduresCollateral networkInvasive natureRepairRecent technical advancementsParaparesisComplicationsParaplegiaInjuryIncidenceVasculatureMonitoring the collateral network pressure in extensive distal aortic aneurysm repair: A new adjunct to prevent ischaemic spinal cord injury
Etz C, Di Luozzo G, Zoli S, Lazalla R, Bodian C, Griepp R. Monitoring the collateral network pressure in extensive distal aortic aneurysm repair: A new adjunct to prevent ischaemic spinal cord injury. The Thoracic And Cardiovascular Surgeon 2011, 59 DOI: 10.1055/s-0030-1269131.Peer-Reviewed Original Research
2010
Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection
Etz CD, Zoli S, Bischoff MS, Bodian C, Di Luozzo G, Griepp RB. Measuring the collateral network pressure to minimize paraplegia risk in thoracoabdominal aneurysm resection. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s125-s130. PMID: 21092778, DOI: 10.1016/j.jtcvs.2010.07.040.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortic Aneurysm, ThoracicBlood PressureBlood Pressure DeterminationCatheterization, PeripheralCentral Venous PressureCerebrospinal Fluid PressureCollateral CirculationDisease Models, AnimalHumansParaplegiaRisk AssessmentRisk FactorsSpinal CordSwineTime FactorsVascular Surgical ProceduresConceptsMean aortic pressureSpinal cord injurySegmental arteriesCord injuryAortic pressureSpinal cord perfusion pressureThoracoabdominal aortic aneurysm repairThoracoabdominal aneurysm resectionSpinal cord perfusionAortic aneurysm repairAneurysm resectionParaplegia riskDistal bypassCord perfusionHypogastric arteryAneurysm repairPerfusion pressureArterial ligationEpidural spaceCollateral networkParavertebral musclesPulsatile perfusionArteryOutflow pressureInjuryPredicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair
Zoli S, Roder F, Etz CD, Brenner RM, Bodian CA, Lin HM, Di Luozzo G, Griepp RB. Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair. The Annals Of Thoracic Surgery 2010, 90: 1237-1245. PMID: 20868820, DOI: 10.1016/j.athoracsur.2010.04.091.Peer-Reviewed Original ResearchConceptsSpinal cord injuryRisk of paraplegiaSegmental arteriesParaplegia riskEndovascular repairAneurysm repairCord injuryThoracoabdominal aortic aneurysm repairMotor-evoked potential monitoringPrevious aortic surgeryThoracoabdominal aneurysm repairIndependent risk factorThoracoabdominal aortic aneurysmsAortic aneurysm repairStandard surgical approachCerebrospinal fluid drainageCrawford classificationHospital mortalitySCI riskAortic surgeryEmergent operationSurgical approachAortic aneurysmRisk factorsAbdominal aortaExperimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk
Zoli S, Etz CD, Roder F, Brenner RM, Bodian CA, Kleinman G, Di Luozzo G, Griepp RB. Experimental Two-Stage Simulated Repair of Extensive Thoracoabdominal Aneurysms Reduces Paraplegia Risk. The Annals Of Thoracic Surgery 2010, 90: 722-729. PMID: 20732484, DOI: 10.1016/j.athoracsur.2010.04.047.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureHind limb functionGroup 2Artery sacrificeLimb functionExtensive segmental artery sacrificeExtensive thoracoabdominal aneurysmsJuvenile Yorkshire pigsSevere ischemic damageMotor-evoked potentialsLumbar spinal cordSpinal cord functionModified Tarlov scoreSpinal cord injuryParaplegia riskTarlov scoreThoracoabdominal aneurysmsAneurysm repairCord functionDistal stumpIschemic damagePerfusion pressureCord injurySpinal cordLower thoracicExtracorporeal Peritoneovenous Shunt for the Management of Postaneurysmectomy Chylous Ascites in a Marfan Patient
Di Luozzo G, Scurlock C, Mechanick JI, Griepp RB. Extracorporeal Peritoneovenous Shunt for the Management of Postaneurysmectomy Chylous Ascites in a Marfan Patient. The Annals Of Thoracic Surgery 2010, 90: 281-284. PMID: 20609797, DOI: 10.1016/j.athoracsur.2009.12.020.Peer-Reviewed Original ResearchConceptsChylous ascitesPeritoneovenous shuntOpen abdominal aortic aneurysm repairAbdominal aortic aneurysm repairAortic aneurysm repairInitial therapeutic interventionAbdominal ascitesAneurysm repairUncommon complicationClinical statusRetroperitoneal surgeryMarfan patientsAscitesTherapeutic interventionsNutritional statusAggressive measuresPatientsShuntStatusComplicationsSurgeryEtiologyMortalityWomenStaged repair significantly reduces paraplegia rate after extensive thoracoabdominal aortic aneurysm repair
Etz CD, Zoli S, Mueller CS, Bodian CA, Di Luozzo G, Lazala R, Plestis KA, Griepp RB. Staged repair significantly reduces paraplegia rate after extensive thoracoabdominal aortic aneurysm repair. Journal Of Thoracic And Cardiovascular Surgery 2010, 139: 1464-1472. PMID: 20494193, DOI: 10.1016/j.jtcvs.2010.02.037.Peer-Reviewed Original ResearchConceptsExtensive thoracoabdominal aortic aneurysm repairExtensive segmental artery sacrificeThoracoabdominal aortic aneurysm repairThoracoabdominal aortic aneurysmsAortic aneurysm repairSpinal cord injuryArtery sacrificeAneurysm repairCord injuryAortic aneurysmCrawford type II thoracoabdominal aortic aneurysmType II thoracoabdominal aortic aneurysmIschemic spinal cord damageChronic obstructive pulmonary diseasePermanent spinal cord injuryExtensive thoracoabdominal aortic aneurysmsCrawford type ICrawford type IIIOverall hospital mortalityPrevious cerebrovascular accidentYear of procedureHypothermic circulatory arrestObstructive pulmonary diseaseOpen surgical repairMotor-evoked potentialsStaged repair significantly reduces paraplegia rate after extensive thoracoabdominal aortic aneurysm repair
Etz C, Zoli S, Mueller C, Roder F, Bischoff M, Bodian C, Di Luozzo G, Griepp R. Staged repair significantly reduces paraplegia rate after extensive thoracoabdominal aortic aneurysm repair. The Thoracic And Cardiovascular Surgeon 2010, 58 DOI: 10.1055/s-0029-1246883.Peer-Reviewed Original Research
2009
Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair
Etz CD, Di Luozzo G, Zoli S, Lazala R, Plestis KA, Bodian CA, Griepp RB. Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1764-1774. PMID: 19463592, DOI: 10.1016/j.athoracsur.2009.02.101.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureDeep hypothermic circulatory arrestThoracoabdominal aortic aneurysmsAortic aneurysm repairHypothermic circulatory arrestNonpulsatile cardiopulmonary bypassCardiopulmonary bypassPerfusion pressureSegmental arteriesEndovascular repairAneurysm repairCirculatory arrestAortic aneurysmThoracoabdominal aortic aneurysm repairNormal spinal cord functionPerfusion pressure monitoringThoracic segmental arteriesMean arterial pressureSpinal cord functionSpinal cord recoveryParaspinal collateral networkArterial pressureCord functionCollateral networkPressure monitoringSupradiaphragmatic Inferior Vena Cava Cannulation for Thoracoabdominal Aortic Aneurysm Repair
Di Luozzo G, Etz CD, Griepp RB. Supradiaphragmatic Inferior Vena Cava Cannulation for Thoracoabdominal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1286-1288. PMID: 19324177, DOI: 10.1016/j.athoracsur.2008.07.025.Peer-Reviewed Original ResearchConceptsSupradiaphragmatic inferior vena cavaThoracoabdominal aortic aneurysm repairDeep hypothermic circulatory arrestFemoral venous accessAortic aneurysm repairHypothermic circulatory arrestInferior vena cavaSite of cannulationThoracoabdominal aneurysmsCirculatory arrestAneurysm repairCardiopulmonary bypassCardiopulmonary supportVenous accessCannulation siteVena cavaPreoperative preparationCannulationRare occasions
2007
Pulmonary Complications After Descending Thoracic and Thoracoabdominal Aortic Aneurysm Repair: Predictors, Prevention, and Treatment
Etz CD, Di Luozzo G, Bello R, Luehr M, Khan MZ, Bodian CA, Griepp RB, Plestis KA. Pulmonary Complications After Descending Thoracic and Thoracoabdominal Aortic Aneurysm Repair: Predictors, Prevention, and Treatment. The Annals Of Thoracic Surgery 2007, 83: s870-s876. PMID: 17257944, DOI: 10.1016/j.athoracsur.2006.10.099.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicAortic RuptureBlood Urea NitrogenFemaleHemorrhageHospital MortalityHumansIntubation, IntratrachealLength of StayMaleMiddle AgedPlatelet TransfusionPrognosisRespiration DisordersRespiration, ArtificialTracheostomyVascular Surgical ProceduresConceptsPreoperative blood urea nitrogenThoracoabdominal aortic aneurysm repairDeep hypothermic circulatory arrestAortic aneurysm repairBlood urea nitrogenHospital stayPulmonary complicationsRespiratory complicationsIndependent predictorsAneurysm repairUrea nitrogenDistal aortic perfusionPreoperative renal insufficiencyProlonged postoperative ventilationMedian hospital stayPostoperative pulmonary complicationsAortic aneurysm surgeryProlonged hospital stayHypothermic circulatory arrestTransfusion of plateletsCurrent retrospective studyFemorofemoral bypassPostoperative ventilationHospital deathPostoperative bleeding