Polypharmacy and risk of falls and fractures for patients with HIV infection and substance dependence
Kim TW, Walley AY, Ventura AS, Patts GJ, Heeren TC, Lerner GB, Mauricio N, Saitz R. Polypharmacy and risk of falls and fractures for patients with HIV infection and substance dependence. AIDS Care 2017, 30: 150-159. PMID: 29034725, PMCID: PMC5977400, DOI: 10.1080/09540121.2017.1384532.Peer-Reviewed Original ResearchConceptsInjection drug useSedating medicationsRisk of fallsMedical attentionAdditional medicationOpioid medicationsHIV infectionSubstance dependenceElectronic medical record reviewNon-ARV medicationsNumber of medicationsMedical record reviewType of medicationSeparate logistic regression modelsCharacteristic curve analysisDSM-IV substance dependenceLogistic regression modelsRecord reviewOdds ratioPolypharmacySuch polypharmacyHigh riskMedicationsGreater oddsOptimal cutoffPolypharmacy and risk of non-fatal overdose for patients with HIV infection and substance dependence
Kim TW, Walley AY, Heeren TC, Patts GJ, Ventura AS, Lerner GB, Mauricio N, Saitz R. Polypharmacy and risk of non-fatal overdose for patients with HIV infection and substance dependence. Journal Of Substance Use And Addiction Treatment 2017, 81: 1-10. PMID: 28847449, PMCID: PMC5966024, DOI: 10.1016/j.jsat.2017.07.007.Peer-Reviewed Original ResearchConceptsNon-fatal overdoseLifetime non-fatal overdoseSedating medicationsInjection drug useOpioid medicationsSubstance dependenceDrug usePast-year substance dependenceSafety-net HIV clinicNon-ARV medicationsSample of PLWHNumber of medicationsMajority of patientsIllicit opioid useType of medicationTotal medicationsHIV clinicMedical comorbiditiesOpioid useHIV infectionOverall medicationSedative useWarrants further researchUnintentional overdoseMedian number