2024
Testing the Feasibility and Acceptability of Using an Artificial Intelligence Chatbot to Promote HIV Testing and Pre-Exposure Prophylaxis in Malaysia: Mixed Methods Study.
Cheah M, Gan Y, Altice F, Wickersham J, Shrestha R, Salleh N, Ng K, Azwa I, Balakrishnan V, Kamarulzaman A, Ni Z. Testing the Feasibility and Acceptability of Using an Artificial Intelligence Chatbot to Promote HIV Testing and Pre-Exposure Prophylaxis in Malaysia: Mixed Methods Study. JMIR Human Factors 2024, 11: e52055. PMID: 38277206, PMCID: PMC10858413, DOI: 10.2196/52055.Peer-Reviewed Original ResearchConceptsUptake of HIV testingHIV testingPre-exposure prophylaxisUnified Theory of AcceptanceFrequency of HIV testingTheory of AcceptanceAI chatbotsPromote HIV testingMental health supportHIV risk assessmentHIV prevention effortsHIV-related informationMixed methods studyPresence of stigmaUse of TechnologyConsequences of HIVEffort expectancySexually transmitted infectionsWeb-based surveyEngaging MSMArtificial intelligenceTranscribed verbatimPrEP uptakeHealth supportMental health
2023
Pre-exposure prophylaxis service among men who have sex with men in Malaysia: findings from a discrete choice experiment
Dubov A, Altice F, Gutierrez J, Wickersham J, Azwa I, Kamarulzaman A, Gautam K, Shrestha R. Pre-exposure prophylaxis service among men who have sex with men in Malaysia: findings from a discrete choice experiment. Scientific Reports 2023, 13: 14200. PMID: 37648731, PMCID: PMC10468492, DOI: 10.1038/s41598-023-41264-5.Peer-Reviewed Original ResearchMeSH KeywordsBayes TheoremHomosexuality, MaleHumansMalaysiaMalePre-Exposure ProphylaxisSexual and Gender MinoritiesConceptsInjectable PrEPPre-exposure prophylaxis servicesDaily oral PrEPPre-exposure prophylaxisMalaysian MSMPrEP deliveryOral PrEPPrEP uptakeMSMPrEPLatent class analysisDiscrete choice experimentMenDelivery preferencesDelivery programsSexGroupClass analysisType of programPreference groupsOnline surveyProphylaxisInitiation rateHIVDosingBarriers and Facilitators to Pre-Exposure Prophylaxis by Men Who Have Sex with Men and Community Stakeholders in Malaysia
Rosen A, Wickersham J, Altice F, Khati A, Azwa I, Tee V, Jeri-Wahrhaftig A, Luces J, Ni Z, Kamarulzaman A, Saifi R, Shrestha R. Barriers and Facilitators to Pre-Exposure Prophylaxis by Men Who Have Sex with Men and Community Stakeholders in Malaysia. International Journal Of Environmental Research And Public Health 2023, 20: 5669. PMID: 37174187, PMCID: PMC10177799, DOI: 10.3390/ijerph20095669.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsHIV InfectionsHomosexuality, MaleHumansMalaysiaMalePre-Exposure ProphylaxisSexual and Gender MinoritiesConceptsPre-exposure prophylaxisPrEP providersNominal group techniqueMalaysian MSMEvidence-based HIV prevention strategiesPatient-centered decision aidAwareness of PrEPHIV prevention strategiesPotential new strategyPrEP deliveryPrEP carePrEP initiationPrEP servicesPrEP uptakeDecision aidPrevention strategiesUnderstanding of barriersComplex clinical protocolsClinical protocolsMSMQualitative focus groupsCommunity stakeholdersPrEPProphylaxisMenClinic-Integrated Smartphone App (JomPrEP) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Mixed Methods Evaluation of Usability and Acceptability
Shrestha R, Altice F, Khati A, Azwa I, Gautam K, Gupta S, Sullivan P, Ni Z, Kamarulzaman A, Phiphatkunarnon P, Wickersham J. Clinic-Integrated Smartphone App (JomPrEP) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Mixed Methods Evaluation of Usability and Acceptability. JMIR MHealth And UHealth 2023, 11: e44468. PMID: 36795465, PMCID: PMC9982718, DOI: 10.2196/44468.Peer-Reviewed Original ResearchMeSH KeywordsAdultHIV InfectionsHIV TestingHomosexuality, MaleHumansMalaysiaMaleMobile ApplicationsPre-Exposure ProphylaxisSexual and Gender MinoritiesConceptsHIV prevention servicesINTERNATIONAL REGISTERED REPORT IDENTIFIERPrevention servicesMean ageHIV preventionPre-exposure prophylaxisHIV prevention outcomesHIV self-testing (HIVST) kitsParticipants' mean ageSelf-testing kitsHealth care settingsMobile health platformMalaysian MSMMixed-methods evaluationHIV testingCare settingsLocal clinicSystem Usability ScalePrevention outcomesDays of testingMSMSmartphone appPrEPHIVMean score
2022
Using nominal group technique to identify barriers and facilitators to preventing HIV using combination same-day pre-exposure prophylaxis and medications for opioid use disorder
Eger WH, Altice FL, Lee J, Vlahov D, Khati A, Osborne S, Wickersham JA, Bohonnon T, Powell L, Shrestha R. Using nominal group technique to identify barriers and facilitators to preventing HIV using combination same-day pre-exposure prophylaxis and medications for opioid use disorder. Harm Reduction Journal 2022, 19: 120. PMID: 36307817, PMCID: PMC9616614, DOI: 10.1186/s12954-022-00703-8.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsHIV InfectionsHumansOpioid-Related DisordersPre-Exposure ProphylaxisSubstance Abuse, IntravenousConceptsSame-day prescriptionPre-exposure prophylaxisOpioid use disorderHIV transmissionUse disordersClinical stakeholdersAvailability of providersSystems of careHealth care systemCoordinated careNew practice modelClinical careMedicationsPharmacy deliveryMOUDNominal group techniqueLocal prescribersPWIDSexual riskPrEPCare systemHealth benefitsCareMultiple visitsProphylaxisA PrEP Demonstration Project Using eHealth and Community Outreach to Justice-Involved Cisgender Women and Their Risk Networks
Meyer JP, Price CR, Ye Y, Qin Y, Tracey D, Demidont AC, Melbourne K, Altice FL. A PrEP Demonstration Project Using eHealth and Community Outreach to Justice-Involved Cisgender Women and Their Risk Networks. AIDS And Behavior 2022, 26: 3807-3817. PMID: 35672552, DOI: 10.1007/s10461-022-03709-2.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsCommunity-Institutional RelationsFemaleHIV InfectionsHumansPre-Exposure ProphylaxisTelemedicineConceptsTDF/FTCPrEP care continuumPre-exposure prophylaxisPrimary care providersPrEP demonstration projectRisk network membersNon-Hispanic whitesCisgender womenOutreach modelRespondent-driven samplingPrEP awarenessCommunity outreach modelEnrolled participantsMean ageClinical criteriaIndex participantsCare continuumHIV preventionSocial comorbiditiesCare providersKey populationsPrEPSubstance useMedical insuranceWomenPreferences for Long-Acting and Alternative Modalities for PrEP among Military Men Who Have Sex with Men: Segmentation Results of an Adaptive Choice-Based Conjoint Analysis Study
Gutierrez JI, Vlahov D, Dubov A, Altice FL. Preferences for Long-Acting and Alternative Modalities for PrEP among Military Men Who Have Sex with Men: Segmentation Results of an Adaptive Choice-Based Conjoint Analysis Study. Journal Of Urban Health 2022, 99: 277-292. PMID: 35318573, PMCID: PMC9033922, DOI: 10.1007/s11524-022-00615-9.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsBayes TheoremHIV InfectionsHomosexuality, MaleHumansMaleMilitary PersonnelPre-Exposure ProphylaxisSexual and Gender Minorities
2021
Preferences for pre-exposure prophylaxis among U.S. military men who have sex with men: results of an adaptive choice based conjoint analysis study
Gutierrez JI, Dubov A, Altice FL, Vlahov D. Preferences for pre-exposure prophylaxis among U.S. military men who have sex with men: results of an adaptive choice based conjoint analysis study. Military Medical Research 2021, 8: 32. PMID: 34006328, PMCID: PMC8132436, DOI: 10.1186/s40779-021-00323-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultBayes TheoremConsumer BehaviorHIV InfectionsHumansMaleMilitary PersonnelPre-Exposure ProphylaxisSexual and Gender MinoritiesSurveys and QuestionnairesUnited StatesConceptsDaily tabletHuman immunodeficiency virus (HIV) infectionMilitary healthcare settingsImmunodeficiency virus infectionPre-exposure prophylaxisU.S. military menTelehealth visitsResultsA totalVirus infectionProvider typeUtility scoresPrEP programHealthcare settingsMental healthMilitary providersProphylaxisMenSexInjectionConjoint analysis studyMilitary menService deliverySocial media groupsMedia groupsMedicationsUse of Pre-exposure Prophylaxis Among People Who Inject Drugs: Exploratory Findings of the Interaction Between Race, Homelessness, and Trust
Zhou X, Altice FL, Chandra D, Didomizio E, Copenhaver MM, Shrestha R. Use of Pre-exposure Prophylaxis Among People Who Inject Drugs: Exploratory Findings of the Interaction Between Race, Homelessness, and Trust. AIDS And Behavior 2021, 25: 3743-3753. PMID: 33751313, DOI: 10.1007/s10461-021-03227-7.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsCross-Sectional StudiesHIV InfectionsHumansIll-Housed PersonsPharmaceutical PreparationsPre-Exposure ProphylaxisSubstance Abuse, IntravenousTrustConceptsPre-exposure prophylaxisPrEP useProvider trustPatient-level factorsOpioid-dependent patientsLogistic regression analysisNon-homeless participantsHomeless participantsRace/ethnicityEligibility criteriaCross-sectional dataPrEPProphylaxisMethadoneRegression analysisDrugsExploratory findingsParticipantsPotential moderatorsPWIDPatientsSignificant moderatorWillingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment
Ni Z, Altice FL, Wickersham JA, Copenhaver MM, DiDomizio EE, Nelson LE, Shrestha R. Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment. Drug And Alcohol Dependence 2021, 219: 108477. PMID: 33422864, PMCID: PMC7946167, DOI: 10.1016/j.drugalcdep.2020.108477.Peer-Reviewed Original ResearchConceptsOpioid-dependent individualsPre-exposure prophylaxisPrEP useHIV riskHealthcare providersSex-related risk behaviorsMultivariable logistic regression analysisAwareness of PrEPUrban methadone clinicMultiple logistic regressionDisproportionate HIV burdenLogistic regression analysisCross-sectional surveyHIV burdenHIV infectionHIV testingIndependent correlatesMethadone clinicsDrug treatmentRisk behaviorsLogistic regressionPrEPPrevious useHigher likelihoodProphylaxis
2020
Development and Psychometric Evaluation of the PrEP Sexual Expectancies (PSEXS) Scale
Dubov A, Ogunbajo A, Altice FL, Fraenkel L, Distelberg B. Development and Psychometric Evaluation of the PrEP Sexual Expectancies (PSEXS) Scale. AIDS And Behavior 2020, 25: 1192-1198. PMID: 33185775, PMCID: PMC7979444, DOI: 10.1007/s10461-020-03087-7.Peer-Reviewed Original ResearchIntegrating HIV pre‐exposure prophylaxis and harm reduction among men who have sex with men and transgender women to address intersecting harms associated with stimulant use: a modelling study
Bórquez A, Rich K, Farrell M, Degenhardt L, McKetin R, Tran LT, Cepeda J, Silva‐Santisteban A, Konda K, Cáceres CF, Kelly S, Altice FL, Martin NK. Integrating HIV pre‐exposure prophylaxis and harm reduction among men who have sex with men and transgender women to address intersecting harms associated with stimulant use: a modelling study. Journal Of The International AIDS Society 2020, 23: e25495. PMID: 32562365, PMCID: PMC7305413, DOI: 10.1002/jia2.25495.Peer-Reviewed Original ResearchConceptsMSM/transgender womenHIV pre-exposure prophylaxisPre-exposure prophylaxisNew HIV infectionsHIV infectionTransgender womenStimulant useCVD mortalityCVD deathHealth harmsIntegrated substance useMore HIV infectionsHigh HIV incidenceCardiovascular disease mortalityRandom allocationUnprotected anal sexRisk of suicideHIV incidenceHIV transmissionDisease mortalityHIV riskGlobal systematic reviewAnal sexReduction interventionsSystematic reviewAwareness about and willingness to use long-acting injectable pre-exposure prophylaxis (LAI-PrEP) among people who use drugs
Shrestha R, DiDomizio EE, Kim RS, Altice FL, Wickersham JA, Copenhaver MM. Awareness about and willingness to use long-acting injectable pre-exposure prophylaxis (LAI-PrEP) among people who use drugs. Journal Of Substance Use And Addiction Treatment 2020, 117: 108058. PMID: 32811633, PMCID: PMC7438607, DOI: 10.1016/j.jsat.2020.108058.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsFemaleHIV InfectionsHomosexuality, MaleHumansMalePatient Acceptance of Health CarePharmaceutical PreparationsPre-Exposure ProphylaxisThailandConceptsPre-exposure prophylaxisInjectable pre-exposure prophylaxisLAI-PrEPOral pre-exposure prophylaxisLong-term side effectsSelf-reported HIV risk behaviorsBangkok Tenofovir StudyEvidence-based HIVHigh-risk PWUDImportant key populationHIV-negative peopleOpioid use disorderHIV risk behaviorsHIV prevention effortsAddiction treatment programsDaily PrEPOral PrEPAdherence challengesIndependent correlatesFemale sexClinical trialsHIV preventionIndependent factorsSide effectsUse disorders
2019
Online HIV information seeking and pre-exposure prophylaxis awareness among people who use drugs
Ranjit YS, Shrestha R, Copenhaver M, Altice FL. Online HIV information seeking and pre-exposure prophylaxis awareness among people who use drugs. Journal Of Substance Use And Addiction Treatment 2019, 111: 16-22. PMID: 32087834, PMCID: PMC7039922, DOI: 10.1016/j.jsat.2019.12.010.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesHIV InfectionsHumansInformation Seeking BehaviorPharmaceutical PreparationsPre-Exposure ProphylaxisSubstance Abuse, IntravenousConceptsHuman immunodeficiency virusHIV informationMethadone treatmentPre-exposure prophylaxis (PrEP) awarenessPre-exposure prophylaxisNew HIV diagnosesHIV-negative PWUDBehavior change continuumCross-sectional surveyMethods of preventionAddiction treatment programsHIV diagnosisImmunodeficiency virusInjection drugsHIV preventionHigh riskGeneral populationSex partnersOverall healthTreatment programPrEPDrugsPWUDChange continuumRiskDual motivational model of pre-exposure prophylaxis use intention: model testing among men who have sex men in Ukraine
Ranjit YS, Dubov A, Polonsky M, Fraenkel L, Rich KM, Ogunbajo A, Altice FL. Dual motivational model of pre-exposure prophylaxis use intention: model testing among men who have sex men in Ukraine. AIDS Care 2019, 32: 261-266. PMID: 31288547, PMCID: PMC6937373, DOI: 10.1080/09540121.2019.1640845.Peer-Reviewed Original ResearchRationale and design of an integrated bio-behavioral approach to improve adherence to pre-exposure prophylaxis and HIV risk reduction among opioid-dependent people who use drugs: The CHRP-BB study
Shrestha R, Altice FL, Sibilio B, Ssenyonjo J, Copenhaver MM. Rationale and design of an integrated bio-behavioral approach to improve adherence to pre-exposure prophylaxis and HIV risk reduction among opioid-dependent people who use drugs: The CHRP-BB study. Contemporary Clinical Trials 2019, 82: 77-84. PMID: 31229618, PMCID: PMC6639056, DOI: 10.1016/j.cct.2019.06.012.Peer-Reviewed Original ResearchConceptsBio-behavioral interventionHIV risk reductionOpioid-dependent peopleMethadone maintenance programPrEP adherenceHIV transmission risk reductionFirst prospective trialPre-exposure prophylaxisHIV prevention strategiesOngoing drug useRisk reductionBehavioral skills modelProspective trialSecondary outcomesPrimary outcomeRisk reduction outcomesHIV riskWeek 20Prevention strategiesUnmet needDrug useHybrid type IBio-behavioral approachProcess evaluationAdherenceEstimated Impact of Targeted Pre-Exposure Prophylaxis: Strategies for Men Who Have Sex with Men in the United States
Elion RA, Kabiri M, Mayer KH, Wohl DA, Cohen J, Beaubrun AC, Altice FL. Estimated Impact of Targeted Pre-Exposure Prophylaxis: Strategies for Men Who Have Sex with Men in the United States. International Journal Of Environmental Research And Public Health 2019, 16: 1592. PMID: 31067679, PMCID: PMC6539923, DOI: 10.3390/ijerph16091592.Peer-Reviewed Original ResearchConceptsYoung Latino MSMYoung Black MSMPre-exposure prophylaxisBlack MSMLatino MSMPrEP useHIV Incidence Risk IndexHuman immunodeficiency virus (HIV) transmissionUse of PrEPNon-PrEP usersLowest NNTHIV infectionNNT valuesHIV prevalenceHIV epidemicHIV preventionMSM populationSubsequent infectionInfection reductionMSMPrevalenceIncidenceVirus transmissionPrEPProphylaxis
2018
Optimizing access to PrEP based on MSM preferences: results of a discrete choice experiment
Dubov A, Ogunbajo A, Altice FL, Fraenkel L. Optimizing access to PrEP based on MSM preferences: results of a discrete choice experiment. AIDS Care 2018, 31: 545-553. PMID: 30554519, PMCID: PMC6408226, DOI: 10.1080/09540121.2018.1557590.Peer-Reviewed Original ResearchConceptsYoung MSMInjectable PrEPPrEP uptakeUptake of PrEPPre-exposure prophylaxisHigh HIV burdenMSM of colorMSM preferencesPrEP administrationDaily PrEPPrEP initiationHIV burdenDemand PrEPConsultation visitMSMPrEP programPrEPLatent class analysisDelivery programsMenGroupClass analysisStructural barriersLow levelsUptakeStigma and Shame Experiences by MSM Who Take PrEP for HIV Prevention: A Qualitative Study
Dubov A, Galbo P, Altice FL, Fraenkel L. Stigma and Shame Experiences by MSM Who Take PrEP for HIV Prevention: A Qualitative Study. American Journal Of Men's Health 2018, 12: 1843-1854. PMID: 30160195, PMCID: PMC6199453, DOI: 10.1177/1557988318797437.Peer-Reviewed Original ResearchMeSH KeywordsAdultHIV InfectionsHumansMaleMenMiddle AgedPre-Exposure ProphylaxisQualitative ResearchSexual and Gender MinoritiesShameSocial StigmaUnited StatesConceptsPrEP stigmaPre-exposure prophylaxis uptakeExperiences of MSMHIV-negative menPrEP-related stigmaHealth care professionalsPrEP useHIV preventionHIV stigmaMSM communityExperiences of stigmaCondom usePrEP programConstant comparison techniquesPrEPSemistructured interviewsMSMStigmaLack of literatureMenQualitative studyMedicationsChemsexPre-exposure Prophylaxis Among Men Who have Sex with Men: Dual Motivational Model of Intention to Use Pre-exposure Prophylaxis
Ranjit YS, Dubov A, Polonsky M, Fraenkel L, Ogunbajo A, Mayer K, Altice FL. Pre-exposure Prophylaxis Among Men Who have Sex with Men: Dual Motivational Model of Intention to Use Pre-exposure Prophylaxis. AIDS And Behavior 2018, 23: 534-543. PMID: 29980993, DOI: 10.1007/s10461-018-2214-2.Peer-Reviewed Original Research