2002
COPII proteins are required for Golgi fusion but not for endoplasmic reticulum budding of the pre-chylomicron transport vesicle
Siddiqi SA, Gorelick FS, Mahan JT, Mansbach CM. COPII proteins are required for Golgi fusion but not for endoplasmic reticulum budding of the pre-chylomicron transport vesicle. Journal Of Cell Science 2002, 116: 415-427. PMID: 12482926, DOI: 10.1242/jcs.00215.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesApolipoprotein B-48Apolipoproteins BCells, CulturedChylomicronsCOP-Coated VesiclesEndoplasmic ReticulumEpithelial CellsGolgi ApparatusIntestinal AbsorptionIntestinal MucosaLipid MetabolismMaleMembrane FusionMicroscopy, ElectronMonomeric GTP-Binding ProteinsProtein TransportRatsSaccharomyces cerevisiae ProteinsVesicular Transport ProteinsConceptsPre-chylomicron transport vesicleCOPII proteinsEndoplasmic reticulumTransport vesiclesBudding of vesiclesSucrose density centrifugationNascent proteinsCargo proteinsProtein vesiclesMembrane proteinsGolgi complexProteinase K treatmentProteinSec24VesiclesGolgiSar1Intestinal GolgiDensity centrifugationReticulumK treatmentTriton XSec13/31Rbet1COPII
1996
Co-distribution of calmodulin-dependent protein kinase II and inositol trisphosphate receptors in an apical domain of gastrointestinal mucosal cells.
Matovcik LM, Maranto AR, Soroka CJ, Gorelick FS, Smith J, Goldenring JR. Co-distribution of calmodulin-dependent protein kinase II and inositol trisphosphate receptors in an apical domain of gastrointestinal mucosal cells. Journal Of Histochemistry & Cytochemistry 1996, 44: 1243-1250. PMID: 8918899, DOI: 10.1177/44.11.8918899.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalcium ChannelsCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium-Calmodulin-Dependent Protein KinasesCell PolarityDigestive SystemFluorescent Antibody Technique, IndirectInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsIntestinal MucosaMaleRabbitsRatsRats, Sprague-DawleyReceptors, Cytoplasmic and NuclearConceptsType 3 InsP3 receptorCaM kinase IICalmodulin-dependent protein kinase IIKinase IIProtein kinase IIInsP3 receptorPotential phosphorylation sitesCalcium/calmodulin-dependent protein kinase IIType 3 inositolPhosphorylation sitesApical domainSubcellular localizationCytoskeletal domainTrisphosphate receptorPancreatic acinar cellsImmunofluorescence microscopyPhysiologic substratesGastrointestinal tissuesRabbit gastric glandsF-actin domainsGastrointestinal mucosal cellsIntestinal enterocytesApical regionAcinar cellsInositol
1983
Duodenal epithelial thymidine uptake in patients with duodenal ulcer or endoscopic duodenitis
Gorelick F, Deluca V, Sheahan D, Marignani P, Goldblatt R, Winnan J, Livstone E. Duodenal epithelial thymidine uptake in patients with duodenal ulcer or endoscopic duodenitis. Digestive Diseases And Sciences 1983, 28: 392-396. PMID: 6839902, DOI: 10.1007/bf02430526.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedCell DivisionDuodenal UlcerDuodenitisDuodenoscopyEpitheliumFemaleHumansIntestinal MucosaMaleMiddle AgedThymidineConceptsEndoscopic duodenitisDuodenal ulcerControl subjectsDuodenal mucosaProliferative indexControl groupChronic active duodenitisDuodenal ulcer diseaseEpithelial cell renewalActive duodenitisChronic duodenitisDuodenal ulcerationMucosal biopsiesUlcer diseaseInflammatory processDuodenitisGastrointestinal tractHistologic appearanceEpithelial proliferationPatientsUlcersCrypt sizeThymidine uptakeMucosaCell renewal
1981
Is gastroduodenitis part of the spectrum of peptic ulcer disease?
DeLuca VA, Winnan GG, Sheahan DG, Sanders FJ, Greenlaw R, Marignani P, Gorelick FS, Bhalotra R, Goldblatt RS. Is gastroduodenitis part of the spectrum of peptic ulcer disease? Journal Of Clinical Gastroenterology 1981, 3: 17-22. PMID: 7320465.Peer-Reviewed Original ResearchConceptsPeptic ulcer diseaseUlcer diseasePeptic ulcerDifferent pathogenetic mechanismsSimilar clinical picturePreliminary dataAcute gastroduodenitisDuodenitis patientsGastrointestinal symptomsDuodenal ulcerUlcer craterAtypical manifestationsClinical pictureProspective studyGastric ulcerControl subjectsPathogenetic mechanismsHistologic studyTreatment responseBland dietGastroduodenitisPatientsProliferative indexThymidine uptakeUlcers