1994
Cell cycle-dependent and kinase-specific regulation of the apical Na/H exchanger and the Na,K-ATPase in the kidney cell line LLC-PK1 by calcitonin.
Chakraborty M, Chatterjee D, Gorelick FS, Baron R. Cell cycle-dependent and kinase-specific regulation of the apical Na/H exchanger and the Na,K-ATPase in the kidney cell line LLC-PK1 by calcitonin. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 2115-2119. PMID: 8134357, PMCID: PMC43320, DOI: 10.1073/pnas.91.6.2115.Peer-Reviewed Original ResearchConceptsNa/H exchangerApical Na/H exchangerH exchangerAmiloride-sensitive 22Na uptakeCell line LLC-PK1Potent natriuretic effectKidney tubulesNa transport systemLLC-PK1K-ATPaseCa/calmodulin-dependent protein kinase IINatriuretic effectSerum calciumCalmodulin-dependent protein kinase IIProximal kidney tubuleCalcitoninCell cycle-specific activationProtein kinase IIReabsorptionTubulesSame cellsKinase IICellsApical exchangerS phase
1990
Rabbit ileal villus cell brush border Na+/H+ exchange is regulated by Ca2+/calmodulin-dependent protein kinase II, a brush border membrane protein.
Cohen ME, Reinlib L, Watson AJ, Gorelick F, Rys-Sikora K, Tse M, Rood RP, Czernik AJ, Sharp GW, Donowitz M. Rabbit ileal villus cell brush border Na+/H+ exchange is regulated by Ca2+/calmodulin-dependent protein kinase II, a brush border membrane protein. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 8990-8994. PMID: 2174171, PMCID: PMC55086, DOI: 10.1073/pnas.87.22.8990.Peer-Reviewed Original ResearchConceptsDependent protein kinase IIProtein kinase IIKinase IIMembrane proteinsSynapsin IDependent protein kinase activityDependent protein kinaseBrush border membranePhosphorylation of sitesProtein kinase activityInhibitor peptideCaM kinase IIBrush border membrane proteinsBorder membraneSpecific inhibitor peptidePhosphopeptide mappingBrush borderProtein kinaseMicrovillus membrane proteinsKinase activityIleal brush-border membraneVillus cell brush border membraneApical membraneKinaseVesicle preparations