2006
Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging
Papaioannou GI, Kasapis C, Seip RL, Grey NJ, Katten D, Wackers FJ, Inzucchi SE, Engel S, Taylor A, Young LH, Chyun DA, Davey JA, Iskandrian AE, Ratner RE, Robinson EC, Carolan S, Heller GV. Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging. Journal Of Nuclear Cardiology 2006, 13: 362-368. PMID: 16750781, DOI: 10.1016/j.nuclcard.2006.01.022.Peer-Reviewed Original ResearchConceptsEndothelium-dependent vasodilationEndothelium-independent vasodilationCoronary artery diseaseMyocardial perfusion imagingRelative myocardial ischemiaAsymptomatic patientsEndothelial functionNegative predictive valueMyocardial ischemiaAsymptomatic type 2 diabetic patientsExclusion of CADPredictive valueAdenosine myocardial perfusion imagingPeripheral vascular endothelial functionType 2 diabetic patientsType 2 diabetes mellitusHigh negative predictive valueAsymptomatic Diabetics (DIAD) studyBrachial artery ultrasonographyVascular endothelial functionDetection of ischemiaEDV responseRelative ischemiaEndothelial dysfunctionOvert atherosclerosis
2004
Randomized, Controlled Dose-Ranging Study of the Selective Adenosine A2A Receptor Agonist Binodenoson for Pharmacological Stress as an Adjunct to Myocardial Perfusion Imaging
Udelson J, Heller G, Wackers F, Chai A, Hinchman D, Coleman P, Dilsizian V, DiCarli M, Hachamovitch R, Johnson J, Barrett R, Gibbons R. Randomized, Controlled Dose-Ranging Study of the Selective Adenosine A2A Receptor Agonist Binodenoson for Pharmacological Stress as an Adjunct to Myocardial Perfusion Imaging. Circulation 2004, 109: 457-464. PMID: 14734517, DOI: 10.1161/01.cir.0000114523.03312.7d.Peer-Reviewed Original ResearchConceptsReversible perfusion defectsDose-related reductionAdenosine receptor stimulationSide effectsPharmacological stressPerfusion defectsReceptor stimulationFrequent side effectsSubjective side effectsDose-Ranging StudyMyocardial perfusion imagingAdenosine A2A receptorsSingle photon emissionChest painCoronary vasodilationCrossover trialBinodenosonA2A receptorsPerfusion imagingSelective agonismRandom orderSeverityKappa valuesSimilar degreePhoton emission
1993
Nuclear Cardiology
Zaret B, Wackers F. Nuclear Cardiology. New England Journal Of Medicine 1993, 329: 775-783. PMID: 8350888, DOI: 10.1056/nejm199309093291107.Peer-Reviewed Original Research
1991
Adenosine or dipyridamole: Which is preferred for myocardial perfusion imaging?
Wackers F. Adenosine or dipyridamole: Which is preferred for myocardial perfusion imaging? Journal Of The American College Of Cardiology 1991, 17: 1295-1296. PMID: 2016446, DOI: 10.1016/s0735-1097(10)80138-x.Peer-Reviewed Original Research
1980
Comparison of exercise radionuclide angiocardiography and thallium-201 myocardial perfusion imaging in coronary artery disease
Johnstone D, Sands M, Berger H, Reduto L, Lachman A, Wackers F, Cohen L, Gottschalk A, Zaret B. Comparison of exercise radionuclide angiocardiography and thallium-201 myocardial perfusion imaging in coronary artery disease. The American Journal Of Cardiology 1980, 45: 1113-1119. PMID: 7377108, DOI: 10.1016/0002-9149(80)90467-1.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseExercise thallium studiesArtery diseaseVentricular reserveEjection fractionThallium studiesPerfusion defectsLeft ventricular ejection fractionThallium-201 myocardial perfusion imagingThallium-201 myocardial perfusionExercise-induced perfusion defectsRegional wall motion abnormalitiesExercise thallium imagesNormal coronary arteriesUpright bicycle exerciseSingle-vessel diseaseT segment depressionVentricular ejection fractionAbnormal exerciseThallium perfusion defectsWall motion abnormalitiesMyocardial perfusion imagingRegional wall motionExercise radionuclideIschemic S