2004
Cardiac Abnormalities in Diabetic Patients With Neuropathy
Johnson BF, Nesto RW, Pfeifer MA, Slater WR, Vinik AI, Chyun DA, Law G, Wackers FJ, Young LH. Cardiac Abnormalities in Diabetic Patients With Neuropathy. Diabetes Care 2004, 27: 448-454. PMID: 14747227, DOI: 10.2337/diacare.27.2.448.Peer-Reviewed Original ResearchMeSH KeywordsAldehyde ReductaseBenzothiazolesCardiac OutputDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NeuropathiesDouble-Blind MethodEnzyme InhibitorsExercise TestFemaleHeartHeart Conduction SystemHeart RateHumansMaleMiddle AgedPhthalazinesPlacebosStroke VolumeThiazolesVentricular Function, LeftConceptsLeft ventricular ejection fractionDiabetic patientsARI treatmentCardiac outputStroke volumeCardiac abnormalitiesAldose reductase inhibitorExercise left ventricular ejection fractionAbnormal heart rate variabilityDiastolic peak filling rateAsymptomatic cardiac abnormalitiesGated radionuclide ventriculographyMaximal bicycle exercisePlacebo-treated subjectsDiastolic filling rateVentricular ejection fractionCoronary artery diseaseValvular heart diseasePeak filling rateExercise cardiac outputLV stroke volumeHeart rate variabilityBlinded treatmentInsulin useArtery disease
1988
Peak filling rate normalized to mitral stroke volume: A new Doppler echocardiographic filling index validated by radionuclide angiographic techniques
Bowman L, Lee F, Jaffe C, Mattera J, Wackers F, Zaret B. Peak filling rate normalized to mitral stroke volume: A new Doppler echocardiographic filling index validated by radionuclide angiographic techniques. Journal Of The American College Of Cardiology 1988, 12: 937-943. PMID: 3417992, DOI: 10.1016/0735-1097(88)90458-5.Peer-Reviewed Original ResearchConceptsPeak filling rateMitral stroke volumeMean peak filling rateEnd-diastolic volumeStroke volumeFilling indexDoppler echocardiographyNormal patientsFilling velocityEarly peak filling velocityLate filling ratioEarly filling velocityDiastolic filling indexesLeft ventricular fillingTime-velocity integralPeak filling velocityRadionuclide angiographic techniquesFilling rateMitral inflowVentricular fillingMitral leafletEchocardiographic determinationMitral apparatusVelocity integralVentricular volume