1990
Comparison of immediate invasive, delayed invasive, and conservative strategies after tissue-type plasminogen activator. Results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II-A trial.
Rogers W, Baim D, Gore J, Brown B, Roberts R, Williams D, Chesebro J, Babb J, Sheehan F, Wackers F. Comparison of immediate invasive, delayed invasive, and conservative strategies after tissue-type plasminogen activator. Results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II-A trial. Circulation 1990, 81: 1457-1476. PMID: 2110033, DOI: 10.1161/01.cir.81.5.1457.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCombined Modality TherapyCoronary AngiographyCoronary Artery BypassExercise TestFemaleHumansMaleMiddle AgedMyocardial InfarctionRadionuclide VentriculographyRandomized Controlled Trials as TopicStroke VolumeThrombolytic TherapyTime FactorsTissue Plasminogen ActivatorConceptsCoronary artery bypass graft surgeryPercutaneous transluminal coronary angioplastyInvasive strategy groupConservative-strategy groupAcute myocardial infarctionTreatment groupsPrimary study end pointResidual infarct artery stenosisArtery bypass graft surgeryPatent infarct-related arteryImmediate invasive strategyPredischarge exercise testingSimilar cumulative ratesBypass graft surgeryStudy end pointInfarct-related arteryTransluminal coronary angioplastyVentricular ejection fractionInitial management strategyLong-term outcomesConservative strategyStrategy groupTissue-type plasminogen activatorNonfatal reinfarctionGraft surgery
1989
Serial quantitative planar technetium-99m isonitrile imaging in acute myocardial infarction: Efficacy for noninvasive assessment of thrombolytic therapy
Wackers F, Gibbons R, Verani M, Kayden D, Pellikka P, Behrenbeck T, Mahmarian J, Zaret B. Serial quantitative planar technetium-99m isonitrile imaging in acute myocardial infarction: Efficacy for noninvasive assessment of thrombolytic therapy. Journal Of The American College Of Cardiology 1989, 14: 861-873. PMID: 2507612, DOI: 10.1016/0735-1097(89)90456-7.Peer-Reviewed Original ResearchConceptsRecombinant tissue-type plasminogen activatorAcute myocardial infarctionPatent infarct-related arteryInfarct-related arteryThallium-201 imagingThrombolytic therapyMyocardial infarctionPlanar technetiumMyocardial perfusionExercise thallium-201 imagingFirst acute myocardial infarctionInfarct-related artery patencyInitial risk areaPersistent coronary occlusionSuccess of reperfusionMyocardial blood flowNew myocardial perfusionTissue-type plasminogen activatorArtery patencyChest painCoronary occlusionRepeat imagingBlood flowInfarctionThallium-201