2003
Electromechanical mapping for detecting myocardial viability and ischemia in patients with severe ischemic cardiomyopathy
Samady H, Liu Y, Choi CJ, Ragosta M, Pfau SE, Cleman MW, Powers ER, Kramer CM, Wackers F, Beller GA, Watson DD. Electromechanical mapping for detecting myocardial viability and ischemia in patients with severe ischemic cardiomyopathy. The American Journal Of Cardiology 2003, 91: 807-811. PMID: 12667565, DOI: 10.1016/s0002-9149(03)00013-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedBody Surface Potential MappingCardiomyopathiesCell SurvivalElectrophysiologic Techniques, CardiacFemaleHumansMaleMiddle AgedMyocardial IschemiaMyocardiumPredictive Value of TestsRadiopharmaceuticalsRestROC CurveSensitivity and SpecificitySeverity of Illness IndexStatistics as TopicStress, PhysiologicalStroke VolumeTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, LeftConceptsSevere ischemic cardiomyopathyIschemic cardiomyopathyViable myocardiumMyocardial viabilityDipyridamole single-photon emissionUnipolar voltageDysfunctional myocardial segmentsBipolar voltageSingle photon emissionDipyridamole SPECTDipyridamole technetiumQuantitative technetiumInducible ischemiaNonviable segmentsNonviable myocardiumElectromechanical mappingMyocardial segmentsTracer uptakePatientsViable segmentsLogistic regressionCardiomyopathyMyocardiumIschemiaSPECT
1997
Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both. The American Journal Of Cardiology 1997, 80: 1007-1013. PMID: 9352969, DOI: 10.1016/s0002-9149(97)00594-8.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePositron emission tomographyLV dysfunctionArtery diseaseGroup 2Myocardial viabilityGroup 1Ejection fractionModerate coronary artery diseaseEmission tomographyModerate LV dysfunctionSevere LV dysfunctionStable angina pectorisLV ejection fractionGlobal LV dysfunctionAccuracy of technetiumSingle photon emissionSemiquantitative SPECTVentricular dysfunctionViability detectionAngina pectorisVentricular functionReduced perfusionSestamibi SPECTMyocardial infarct
1996
Resting Tc-99m sestamibi SPECT underestimates myocardial viability in patients with severe ischemic left ventricular dysfunction: Comparison with ammonia/FDG PET
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Resting Tc-99m sestamibi SPECT underestimates myocardial viability in patients with severe ischemic left ventricular dysfunction: Comparison with ammonia/FDG PET. Journal Of The American College Of Cardiology 1996, 27: 162. DOI: 10.1016/s0735-1097(96)80876-x.Peer-Reviewed Original Research
1992
Tc-99m SestaMIBI: Will it replace Tl-201 in clinical cardiology?
Wackers F. Tc-99m SestaMIBI: Will it replace Tl-201 in clinical cardiology? Developments In Cardiovascular Medicine 1992, 128: 239-248. DOI: 10.1007/978-94-011-2666-3_16.Peer-Reviewed Original ResearchCoronary artery diseaseArtery diseaseEjection fractionPharmacological vasodilatationPhysical exerciseTl-201Regional wall motion studiesFirst-pass ejection fractionVentricular ejection fractionSize of infarctionAcute myocardial infarctionMyocardial perfusion imagingRegional wall motionMyocardial blood flowWall motion studiesThousands of patientsLower extraction fractionMyocardial salvageThrombolytic therapyVentricular functionCoronary occlusionMyocardial infarctionMyocardial ischemiaSestamibi imagingMyocardial viability
1991
Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest
Kayden D, Sigal S, Soufer R, Mattera J, Zaret B, Wackers F. Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest. Journal Of The American College Of Cardiology 1991, 18: 1480-1486. PMID: 1939949, DOI: 10.1016/0735-1097(91)90678-3.Peer-Reviewed Original ResearchConceptsInjection of thalliumRedistribution imagesDefect reversibilityThallium-201 reinjectionThallium-201 defectsLate redistribution imagingPoor quality studiesDiagnostic informationClinical variablesRedistribution imagingThallium defectsThallium imagesMyocardial viabilityReversible defectsStress imagingThallium-201PatientsBetter diagnostic informationStress testingExercisePresent studyQuality studiesInjectionLate redistributionReinjection