2018
Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodules
2017
Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database
Korst RJ, Fernando S, Catlin AC, Rutledge JR, Girard N, Huang J, Detterbeck F, Database C. Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database. The Annals Of Thoracic Surgery 2017, 104: 1815-1820. PMID: 29033016, PMCID: PMC5785101, DOI: 10.1016/j.athoracsur.2017.06.053.Peer-Reviewed Original ResearchConceptsPositron emission tomographyInternational Thymic Malignancy Interest GroupHistologic typeThymic malignanciesPretreatment workupPathologic stageEmission tomographyProspective databaseThymic tumorsTumor stageMaximum standardized uptake valueProspective research databaseHistologic tumor typeThymic epithelial tumorsStandardized uptake valueCharacteristic curveAnalysis of receiverClinicopathologic featuresRare tumorEpithelial tumorsLarge cohortResearch DatabaseUptake valueTumor typesPatients