2015
Relation of atherogenic lipoproteins with estimated glomerular filtration rate decline: a longitudinal study
Lin J, Khetarpal SA, Terembula K, Reilly MP, Wilson FP. Relation of atherogenic lipoproteins with estimated glomerular filtration rate decline: a longitudinal study. BMC Nephrology 2015, 16: 130. PMID: 26238454, PMCID: PMC4545861, DOI: 10.1186/s12882-015-0122-5.Peer-Reviewed Original ResearchConceptsMin/yearPenn Diabetes Heart StudyApoC-III levelsBaseline plasmaApoC-IIIGlomerular filtration rate declineSingle-center observational cohortBackgroundChronic kidney diseaseClinical CV diseaseLipid medication usePre-existing CKDCardiovascular risk factorsBaseline plasma levelsGlomerular filtration rateSlope of eGFRAtherogenic lipid fractionsCausal cardiovascular risk factorDiabetes Heart StudyCKD progressionEGFR declineCV diseaseObservational cohortBaseline triglyceridesMedication useMultivariable analysis
2014
Plasma Lipoprotein(a) Levels Are Associated with Mild Renal Impairment in Type 2 Diabetics Independent of Albuminuria
Lin J, Reilly MP, Terembula K, Wilson FP. Plasma Lipoprotein(a) Levels Are Associated with Mild Renal Impairment in Type 2 Diabetics Independent of Albuminuria. PLOS ONE 2014, 9: e114397. PMID: 25490096, PMCID: PMC4260843, DOI: 10.1371/journal.pone.0114397.Peer-Reviewed Original ResearchConceptsPenn Diabetes Heart StudyGFR impairmentT2DM patientsRisk factorsModifiable CV risk factorsSingle-center observational cohortAtherogenic lipid profileCV risk factorsMild renal impairmentIndependent risk factorNormal renal functionWorse kidney functionType 2 diabeticsCKD-EPI equationDiabetes Heart StudyCross-sectional analysisLogistic regression modelsClinical CVDMild CKDCV diseaseRenal impairmentObservational cohortRenal functionCV preventionDiabetic counterparts