2011
Bone Regeneration of Tibial Segmental Defect Using Isotropic-Pore Structures Hydroxyapatite/Alumina Bi-Layered Scaffold: In Vivo Pilot Study
Son J, Kim JM, Han M, Choi S, Lee F, Oh D. Bone Regeneration of Tibial Segmental Defect Using Isotropic-Pore Structures Hydroxyapatite/Alumina Bi-Layered Scaffold: In Vivo Pilot Study. Journal Of Long-Term Effects Of Medical Implants 2011, 21: 159-167. PMID: 22043974, DOI: 10.1615/jlongtermeffmedimplants.v21.i2.60.Peer-Reviewed Original ResearchConceptsBi-layer scaffoldLayered scaffoldsBi-layered scaffoldIsotropic pore structureLarge segmental defectsEnergy dispersive spectroscopyBone regenerationAlumina scaffoldsCoating techniqueDispersive spectroscopyPore sizeSegmental defectsTibia modelBone substituteTibial segmental defectInner layerAluminaElectron microscopyOuter layerBone defectsMicro-CTNew bone formationLayerScaffoldsPorosity
2002
Repair of Bone Allograft Fracture Using Bone Morphogenetic Protein-2
Lee FY, Storer S, Hazan EJ, Gebhardt MC, Mankin HJ. Repair of Bone Allograft Fracture Using Bone Morphogenetic Protein-2. Clinical Orthopaedics And Related Research® 2002, 397: 119-126. PMID: 11953604, DOI: 10.1097/00003086-200204000-00017.Peer-Reviewed Original ResearchConceptsAllograft fractureNormal fracture healingFracture healingProtein 2Long-term clinical dataExtensive tumour surgeryBone morphogenetic protein-2Major revision surgeryMorphogenetic protein-2Experimental groupOnly fibrosisRadiographic unionNew bone formationRevision surgeryAdditional ratsClinical dataTumor surgeryBone allograftAllograft boneControl groupBiologic regulatorsOsteotomy siteFracture repairRecombinant human bone morphogenetic protein-2Adequate function