2014
Complete remission of childhood-onset epilepsy: stability and prediction over two decades
Berg AT, Rychlik K, Levy SR, Testa FM. Complete remission of childhood-onset epilepsy: stability and prediction over two decades. Brain 2014, 137: 3213-3222. PMID: 25338950, PMCID: PMC4240301, DOI: 10.1093/brain/awu294.Peer-Reviewed Original ResearchConceptsComplete remissionSeizure resolutionSeizure outcomeInitial diagnosisChildhood epilepsyLast contactCourse of epilepsyChildhood-onset epilepsySelf-limited epilepsy syndromeProportional hazards modelProspective cohortBaseline factorsRelapse rateLate remissionEpilepsy syndromesComplete resolutionRemissionHazards modelPredictive valueEpilepsyLogistic regressionConnecticut StudyDiagnosisFurther treatmentDevelopmental problemsLong‐term seizure remission in childhood absence epilepsy: Might initial treatment matter?
Berg AT, Levy SR, Testa FM, Blumenfeld H. Long‐term seizure remission in childhood absence epilepsy: Might initial treatment matter? Epilepsia 2014, 55: 551-557. PMID: 24512528, PMCID: PMC3999182, DOI: 10.1111/epi.12551.Peer-Reviewed Original ResearchConceptsChildhood absence epilepsyComplete remissionAtypical EEG featuresValproic acidEarly remissionAbsence epilepsyLong-term seizure outcomeLong-term seizure remissionPotential disease-modifying effectsPrimary long-term outcomeCommunity-based cohort studySignificant imaging abnormalitiesDisease-modifying effectsInitial treatment choiceLong-term outcomesInitial success rateGenetic absence modelSupporting Information sectionSeizure outcomeCohort studyFirst medicationSeizure remissionConvulsive seizuresImaging abnormalitiesInitial medication
2011
Complete remission in nonsyndromic childhood‐onset epilepsy
Berg AT, Testa FM, Levy SR. Complete remission in nonsyndromic childhood‐onset epilepsy. Annals Of Neurology 2011, 70: 566-573. PMID: 21710620, PMCID: PMC3183287, DOI: 10.1002/ana.22461.Peer-Reviewed Original ResearchConceptsComplete remissionNonsyndromic epilepsyProspective community-based cohortEarly seizure controlChildhood-onset epilepsyCommunity-based cohortProportional hazard modelingRisk of relapseKaplan-Meier approachSeizure outcomeSeizure controlSubsequent seizuresInitial diagnosisMultivariable analysisRemissionCohort membersEarly predictorBivariate analysisHazard modelingPoor chanceOlder ageRelapseEpilepsyCauseAge effects
2006
How long does it take for epilepsy to become intractable? A prospective investigation
Berg AT, Vickrey BG, Testa FM, Levy SR, Shinnar S, DiMario F, Smith S. How long does it take for epilepsy to become intractable? A prospective investigation. Annals Of Neurology 2006, 60: 73-79. PMID: 16685695, DOI: 10.1002/ana.20852.Peer-Reviewed Original ResearchConceptsEarly remission periodSeizures/monthCatastrophic epilepsyFurther remissionTreatable epilepsyProspective cohortRemission periodEpilepsy syndromesIntractable epilepsyProspective InvestigationFocal epilepsyLast contactEpilepsyEpilepsy diagnosisRemissionSyndromeMore yearsChildrenMonthsDrugsYearsSurgerySeizuresReferralCohort