2023
Cross-hemicord spinal fiber reorganization associates with cortical sensory and motor network expansion in the rat model of hemicontusion cervical spinal cord injury
Mihailovic J, Sanganahalli B, Hyder F, Chitturi J, Elkabes S, Heary R, Kannurpatti S. Cross-hemicord spinal fiber reorganization associates with cortical sensory and motor network expansion in the rat model of hemicontusion cervical spinal cord injury. Neuroscience Letters 2023, 820: 137607. PMID: 38141752, PMCID: PMC10797561, DOI: 10.1016/j.neulet.2023.137607.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCervical spinal cord injuryDiffusion tensor imagingCord injurySpinal cordCervical spinal cordState functional connectivitySpinal cord samplesSpinal cord diffusion tensor imagingMagnetic resonance imagingBrain functional MRIInjury epicenterSpinal reorganizationPost-SCINeuroplastic changesCord samplesCortical sensoryRat modelTraumatic injuryMD changeMotor networkNervous systemResonance imagingSingle-subject levelFunctional MRI
2016
Chapter 5 New horizons in neurometabolic and neurovascular coupling from calibrated fMRI
Shu CY, Sanganahalli BG, Coman D, Herman P, Hyder F. Chapter 5 New horizons in neurometabolic and neurovascular coupling from calibrated fMRI. Progress In Brain Research 2016, 225: 99-122. PMID: 27130413, DOI: 10.1016/bs.pbr.2016.02.003.Peer-Reviewed Original ResearchConceptsNeurovascular couplingFunctional MRINeuronal activityBlood oxygenation level-dependent (BOLD) signalFunctional brain activationLevel-dependent signalNeurometabolic couplingEffective therapyBlood flowNeuroimaging toolsHealth conditionsPowerful neuroimaging toolBrain activationBOLD signalNeural activityBOLD contrastMetabolic demandsOxygen consumptionDependent signalsTherapyMicrovesselsMRIActivityBiomarkers
2013
Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI
Herman P, Sanganahalli BG, Blumenfeld H, Rothman DL, Hyder F. Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 15115-15120. PMID: 23980158, PMCID: PMC3773779, DOI: 10.1073/pnas.1307154110.Peer-Reviewed Original ResearchConceptsCerebral blood volumeLocal field potentialsMultiunit activitySomatosensory cortexCortical laminaeBlood oxygenation level-dependent (BOLD) signalRat somatosensory cortexLevel-dependent signalNeurometabolic couplingCerebral cortexSuperficial laminaeCBF changesDeep laminaeMagnetic resonance imaging dataBlood flowQuantitative neuroimagingBlood volumeFunctional MRISensory stimulationBOLD signalOxidative metabolismCortexLayer-specific responsesMetabolic measurementsField potentials
2008
Coding of Peripheral Olfactory Information in the Olfactory Bulb of Small Animals
Xu F, Shafer J, Liu N, Rothman D, Hyder F, Shepherd G. Coding of Peripheral Olfactory Information in the Olfactory Bulb of Small Animals. 2008, 279-283. DOI: 10.1007/978-1-4020-8387-7_49.Peer-Reviewed Original Research
2003
Neuroenergetic Basis of Functional MRI: Implications for Efficiency of Brain Work
Hyder F. Neuroenergetic Basis of Functional MRI: Implications for Efficiency of Brain Work. 2003, 73-74. DOI: 10.1109/nebc.2003.1215998.Peer-Reviewed Original ResearchNeural activityLocal energy metabolismEnergy metabolismActual neuronal activitiesNeuronal excitabilityRat brainBlood flowNeuronal activityExtracellular recordingsFunctional MRIBlood oxygenationSensory stimulationBlood vesselsOxidative metabolismNeuronal ensemblesMRI mapsFMRI signalsBrain workNeural basisMetabolismFMRIFMRI dataExcitabilityActivityBrain
2002
Quantitative fMRI of rat brain by multi-modal MRI and MRS measurements
Hyder F, Kida I, Smith A, Blumenfeld H, Shulman R, Rothman D. Quantitative fMRI of rat brain by multi-modal MRI and MRS measurements. International Congress Series 2002, 1235: 57-71. DOI: 10.1016/s0531-5131(02)00173-5.Peer-Reviewed Original ResearchMagnetic resonance imagingRat brainNeuronal activityFunctional MRIBOLD fMRI signalCerebral cortexNeuronal glucose oxidationRat cerebral cortexFunctional magnetic resonance imagingFMRI signalsBOLD functional MRIQuantitative magnetic resonance imagingBlood oxygenation levelBOLD fMRI studiesMulti-modal magnetic resonance imagingQuantitative functional MRIGlutamatergic neuronsOxygen deliveryPhysiologic basisResonance imagingPhysiologic componentsCMRO2BrainBlood circulationOxygenation level
2001
Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI
Hyder F, Kida I, Behar K, Kennan R, Maciejewski P, Rothman D. Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI. NMR In Biomedicine 2001, 14: 413-431. PMID: 11746934, DOI: 10.1002/nbm.733.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingNeuronal activityBOLD functional MRIFunctional MRICerebral cortexPharmacological treatmentGlutamate release inhibitorNeuronal glucose oxidationRat cerebral cortexRelease of glutamateRat forepaw stimulation modelFMRI signalsFunctional magnetic resonance imagingQuantitative magnetic resonance imagingBlood oxygenation levelBOLD fMRI studiesEnergy metabolismBOLD fMRI signalMulti-modal magnetic resonance imagingGlutamatergic neuronsRelease inhibitorChannel blockersRat brainOxygen deliveryNeurochemical basis
2000
Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI
Xu F, Kida I, Hyder F, Shulman R. Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 10601-10606. PMID: 10973488, PMCID: PMC27071, DOI: 10.1073/pnas.180321397.Peer-Reviewed Original ResearchConceptsRat olfactory bulbOlfactory bulbFunctional MRIBlood oxygenation level-dependent (BOLD) functional MRILevel-dependent functional MRIReceptor cellsExternal plexiform layerOlfactory nerve layerEntire olfactory bulbSpatial activity patternsFunctional MRI resultsNerve layerPlexiform layerGlomerular layerMRI resultsOdor stimuliIAA exposureMRIActivity patternsExposureLonger exposureDifferent concentrationsDifferent subsetsBulbCells
1997
Functional MRI bold signal coincides with electrical activity in the rat whisker barrels
Yang X, Hyder F, Shulman R. Functional MRI bold signal coincides with electrical activity in the rat whisker barrels. Magnetic Resonance In Medicine 1997, 38: 874-877. PMID: 9402186, DOI: 10.1002/mrm.1910380604.Peer-Reviewed Original ResearchConceptsRat whisker barrelsElectrical activityFunctional MRIWhisker barrelsBlood oxygenation level-dependent (BOLD) image contrastBrain functional activityBOLD fMRI signalNeuronal electrical activitySustained stimulationFunctional activationNoninvasive methodFunctional activityFMRI signalsPerfusionRat whiskerLocalized increaseActivityMRI“Willed action”: A functional MRI study of the human prefrontal cortex during a sensorimotor task
Hyder F, Phelps E, Wiggins C, Labar K, Blamire A, Shulman R. “Willed action”: A functional MRI study of the human prefrontal cortex during a sensorimotor task. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 6989-6994. PMID: 9192679, PMCID: PMC21272, DOI: 10.1073/pnas.94.13.6989.Peer-Reviewed Original ResearchConceptsDorsolateral prefrontal cortexPrefrontal cortexVerbal fluency taskFunctional MRISensorimotor tasksPositron emission tomography studyLeft dorsolateral prefrontal cortexEmission tomography studiesFunctional MRI studyFluency taskWilled actionHuman prefrontal cortexHealthy subjectsPET resultsMRI studiesBilateral activationCoronal slicesPET studiesTomography studyCortexFMRI dataFMRI studyActivation fociBrain activityHuman brain activity