2016
Chapter 5 New horizons in neurometabolic and neurovascular coupling from calibrated fMRI
Shu CY, Sanganahalli BG, Coman D, Herman P, Hyder F. Chapter 5 New horizons in neurometabolic and neurovascular coupling from calibrated fMRI. Progress In Brain Research 2016, 225: 99-122. PMID: 27130413, DOI: 10.1016/bs.pbr.2016.02.003.Peer-Reviewed Original ResearchConceptsNeurovascular couplingFunctional MRINeuronal activityBlood oxygenation level-dependent (BOLD) signalFunctional brain activationLevel-dependent signalNeurometabolic couplingEffective therapyBlood flowNeuroimaging toolsHealth conditionsPowerful neuroimaging toolBrain activationBOLD signalNeural activityBOLD contrastMetabolic demandsOxygen consumptionDependent signalsTherapyMicrovesselsMRIActivityBiomarkers
2012
Quantitative fMRI and oxidative neuroenergetics
Hyder F, Rothman DL. Quantitative fMRI and oxidative neuroenergetics. NeuroImage 2012, 62: 985-994. PMID: 22542993, PMCID: PMC3389300, DOI: 10.1016/j.neuroimage.2012.04.027.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingNeuronal activityQuantitative functional magnetic resonance imagingTotal neuronal activityBlood oxygenation level-dependent (BOLD) signalBrain energy metabolismResting-state paradigmLevel-dependent signalMagnetic resonance imagingSynaptic activityResonance imagingParamagnetic contrast agentFunctional brainBOLD contrastBaseline stateEnergy metabolismFunctional mapsContrast agentsMagnetic resonance spectroscopyFMRI dataRegion of interestActivityNeuroenergeticsBrain
2003
Neuroenergetic Basis of Functional MRI: Implications for Efficiency of Brain Work
Hyder F. Neuroenergetic Basis of Functional MRI: Implications for Efficiency of Brain Work. 2003, 73-74. DOI: 10.1109/nebc.2003.1215998.Peer-Reviewed Original ResearchNeural activityLocal energy metabolismEnergy metabolismActual neuronal activitiesNeuronal excitabilityRat brainBlood flowNeuronal activityExtracellular recordingsFunctional MRIBlood oxygenationSensory stimulationBlood vesselsOxidative metabolismNeuronal ensemblesMRI mapsFMRI signalsBrain workNeural basisMetabolismFMRIFMRI dataExcitabilityActivityBrain
1997
Functional MRI bold signal coincides with electrical activity in the rat whisker barrels
Yang X, Hyder F, Shulman R. Functional MRI bold signal coincides with electrical activity in the rat whisker barrels. Magnetic Resonance In Medicine 1997, 38: 874-877. PMID: 9402186, DOI: 10.1002/mrm.1910380604.Peer-Reviewed Original ResearchConceptsRat whisker barrelsElectrical activityFunctional MRIWhisker barrelsBlood oxygenation level-dependent (BOLD) image contrastBrain functional activityBOLD fMRI signalNeuronal electrical activitySustained stimulationFunctional activationNoninvasive methodFunctional activityFMRI signalsPerfusionRat whiskerLocalized increaseActivityMRI