2020
Exploring response inhibition and error monitoring in obsessive-compulsive disorder
Silveira V, Frydman I, Fontenelle L, Mattos P, de Oliveira-Souza R, Moll J, Hoexter M, Miguel E, McLaughlin N, Shephard E, Batistuzzo M. Exploring response inhibition and error monitoring in obsessive-compulsive disorder. Journal Of Psychiatric Research 2020, 126: 26-33. PMID: 32413597, PMCID: PMC7313630, DOI: 10.1016/j.jpsychires.2020.04.002.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrazilHumansInhibition, PsychologicalLinear ModelsNeuroimagingObsessive-Compulsive DisorderConceptsObsessive-compulsive disorderError monitoringNon-psychiatric controlsResponse inhibitionStop-signal taskBehavioral evidenceEffect sizeRecent neuroimaging workImpaired response inhibitionPreliminary behavioral evidenceMedium effect sizeLarge effect sizesNeuroimaging workBehavioral measuresSmall effect sizesPossible moderatorsOCD severitySymptomatic patientsClinical factorsEM performancePossible associationDifferential effects
2017
Personality measures after gamma ventral capsulotomy in intractable OCD
Paiva R, Batistuzzo M, McLaughlin N, Canteras M, de Mathis M, Requena G, Shavitt R, Greenberg B, Norén G, Rasmussen S, Tavares H, Miguel E, Lopes A, Hoexter M. Personality measures after gamma ventral capsulotomy in intractable OCD. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2017, 81: 161-168. PMID: 29100975, DOI: 10.1016/j.pnpbp.2017.10.023.Peer-Reviewed Original Research
2016
Epigenetic evidence for involvement of the oxytocin receptor gene in obsessive–compulsive disorder
Cappi C, Diniz J, Requena G, Lourenço T, Lisboa B, Batistuzzo M, Marques A, Hoexter M, Pereira C, Miguel E, Brentani H. Epigenetic evidence for involvement of the oxytocin receptor gene in obsessive–compulsive disorder. BMC Neuroscience 2016, 17: 79. PMID: 27903255, PMCID: PMC5131547, DOI: 10.1186/s12868-016-0313-4.Peer-Reviewed Original Research
2015
Positive Attributes Buffer the Negative Associations Between Low Intelligence and High Psychopathology With Educational Outcomes
Hoffmann M, Leibenluft E, Stringaris A, Laporte P, Pan P, Gadelha A, Manfro G, Miguel E, Rohde L, Salum G. Positive Attributes Buffer the Negative Associations Between Low Intelligence and High Psychopathology With Educational Outcomes. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 55: 47-53. PMID: 26703909, PMCID: PMC4695393, DOI: 10.1016/j.jaac.2015.10.013.Peer-Reviewed Original ResearchConceptsNegative educational outcomesConfirmatory factor analysisEducational outcomesPoor academic performanceLow intelligenceHigher psychopathologyAcademic performancePositive attributesNegative school outcomesPsychiatric symptomsHigher psychiatric symptomsDistinct constructsSchool outcomesEducational problemsCommunity sampleDiscriminant validityPsychopathologyNegative effectsFactor analysisIntelligenceMain effectEquation modelNegative associationAttribute changesLow levelsReduced Prefrontal Activation in Pediatric Patients With Obsessive-Compulsive Disorder During Verbal Episodic Memory Encoding
Batistuzzo M, Balardin J, da Graça Morais Martin M, Hoexter M, Bernardes E, Borcato S, de Marco e Souza M, Querido C, Morais R, de Alvarenga P, Lopes A, Shavitt R, Savage C, Amaro E, Miguel E, Polanczyk G, Miotto E. Reduced Prefrontal Activation in Pediatric Patients With Obsessive-Compulsive Disorder During Verbal Episodic Memory Encoding. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 849-858. PMID: 26407495, DOI: 10.1016/j.jaac.2015.06.020.Peer-Reviewed Original ResearchConceptsVerbal episodic memoryObsessive-compulsive disorderEpisodic memoryOrbitofrontal cortexPrefrontal cortexSemantic clusteringFunctional magnetic resonance imagingDorsomedial prefrontal cortexAltered brain activationDifferent neural mechanismsPathophysiology of OCDUnrelated wordsPrefrontal activationBrain activationWord listsExecutive dysfunctionNeural mechanismsTotal wordsCompulsive Scale scoresYale-Brown Obsessive Compulsive Scale scoresStrategy scoresStrategy applicationMemoryCortexKey regions
2006
Clinical features associated with treatment response in obsessive-compulsive disorder
Shavitt R, Belotto C, Curi M, Hounie A, Rosário-Campos M, Diniz J, Ferrão Y, Pato M, Miguel E. Clinical features associated with treatment response in obsessive-compulsive disorder. Comprehensive Psychiatry 2006, 47: 276-281. PMID: 16769302, DOI: 10.1016/j.comppsych.2005.09.001.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresPharmacological treatmentTreatment responseEarly onsetConsecutive adult patientsFourth Edition criteriaSensory phenomenaEarly-onset obsessive-compulsive disorderYale-Brown ObsessiveOral clomipramineClomipramine treatmentAdult patientsPoor prognosisPoor responseSao Paulo SchoolDisorders ClinicTic disordersEdition criteriaScore decreaseFavorable responseLinear regression analysisMental disordersStatistical ManualDisorders