2023
Longitudinal invariance of psychotic experiences in children and adolescents: What do the data tell us?
Barbosa M, Machado V, Ziebold C, Moriyama T, Bressan R, Pan P, Rohde L, Miguel E, Fonseca L, Van Os J, Gadelha A. Longitudinal invariance of psychotic experiences in children and adolescents: What do the data tell us? Schizophrenia Research 2023, 255: 33-40. PMID: 36958268, DOI: 10.1016/j.schres.2023.03.003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildFactor Analysis, StatisticalHumansPsychometricsPsychotic DisordersReproducibility of ResultsSchoolsSurveys and QuestionnairesConceptsPsychotic experiencesTime pointsHigh-risk cohortPrevious systematic reviewDifferent age groupsDifferent time pointsBaseline evaluationLifetime psychotic experiencesPositive symptomsSystematic reviewAge groupsPerceptual abnormalitiesLongitudinal studyBrazilian High-Risk CohortPsychosis pronenessGood model fit indicesThree-factor solutionChildren
2021
How do daily routines and situational factors affect the severity of obsessive-compulsive disorder?
Brierley M, Albertella L, do Rosário M, Ferrão Y, Miguel E, Fontenelle L. How do daily routines and situational factors affect the severity of obsessive-compulsive disorder? Journal Of Psychiatric Research 2021, 143: 395-399. PMID: 34600268, DOI: 10.1016/j.jpsychires.2021.09.040.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderOCD symptom severitySymptom severityOCD symptomsOCD patientsSevere OCD symptomsYale-Brown ObsessiveCross-sectional designReport symptomsHistory questionnaireCommon biological abnormalitiesBiological abnormalitiesClinical implicationsSymptomsDaily routineCompulsive ScaleSeverityMultivariate regressionPatientsRoutine factorsDisorders
2020
Social losses predict a faster onset and greater severity of obsessive-compulsive disorder
Destrée L, Albertella L, Torres A, Ferrão Y, Shavitt R, Miguel E, Fontenelle L. Social losses predict a faster onset and greater severity of obsessive-compulsive disorder. Journal Of Psychiatric Research 2020, 130: 187-193. PMID: 32828024, DOI: 10.1016/j.jpsychires.2020.07.027.Peer-Reviewed Original ResearchConceptsClinical obsessive-compulsive disorderObsessive-compulsive disorderStressful life eventsSpeed of progressionYale-Brown ObsessiveDSM-IV Axis I DisordersLife eventsCompulsive ScaleAxis I DisordersStructured Clinical InterviewSeverity of symptomsSymptom dimensionsBeck Depression InventorySubclinical obsessive-compulsive symptomsBeck Anxiety InventorySpecific obsessive-compulsive symptom dimensionsI disordersFaster onsetPsychiatric disordersHistory questionnaireBrown AssessmentClinical InterviewGreater severityDepression InventoryObsessive-compulsive symptoms
2018
Prevalência de problemas de saúde mental na infância na atenção primária
Fatori D, Brentani A, Grisi S, Miguel E, Graeff-Martins A. Prevalência de problemas de saúde mental na infância na atenção primária. Ciência & Saúde Coletiva 2018, 23: 3013-3020. PMID: 30281738, DOI: 10.1590/1413-81232018239.25332016.Peer-Reviewed Original ResearchConceptsMental health problemsPrimary healthcare unitsHealth professionalsHealth problemsPrimary care settingHealth service usePrevalence of internalizingPublic health problemPresent population studyMental health professionalsMedication treatmentYear old childrenHigh prevalenceCare settingsAtenção primáriaService useHealth servicesSample of childrenOlder childrenPrevalenceTreatment constituteDifficulties QuestionnairePopulation studiesHealthcare unitsChildrenSocioeconomic diversities and infant development at 6 to 9 months in a poverty area of São Paulo, Brazil
Tella P, da Rosa Piccolo L, Rangel M, Rohde L, Polanczyk G, Miguel E, Grisi S, Fleitlich-Bilyk B, Ferraro A. Socioeconomic diversities and infant development at 6 to 9 months in a poverty area of São Paulo, Brazil. Trends In Psychiatry And Psychotherapy 2018, 40: 232-240. PMID: 30156646, DOI: 10.1590/2237-6089-2017-0008.Peer-Reviewed Original ResearchMeSH KeywordsBrazilChild DevelopmentCitiesCognitionCross-Sectional StudiesFemaleHumansInfantLanguageMaleMotor SkillsPoverty AreasRisk FactorsSurveys and QuestionnairesConceptsCognitive developmentInfant developmentInfant languageInfants' performanceMaternal educationCognitive scoresMotor skillsSocioeconomic statusIntervention effortsBayley ScalesHigh languageSES effectsParticipant familiesEarly childhoodMotor ScaleLanguageSocioeconomic backgroundHigher maternal educationPositive associationChildhoodSocioeconomic diversityInfancySkillsFirst yearChildrenObsessive-compulsive symptoms in children with first degree relatives diagnosed with obsessive-compulsive disorder
Chacon P, Bernardes E, Faggian L, Batistuzzo M, Moriyama T, Miguel E, Polanczyk G. Obsessive-compulsive symptoms in children with first degree relatives diagnosed with obsessive-compulsive disorder. Brazilian Journal Of Psychiatry 2018, 40: 388-393. PMID: 29898190, PMCID: PMC6899383, DOI: 10.1590/1516-4446-2017-2321.Peer-Reviewed Original ResearchConceptsPresence of OCSObsessive-compulsive disorderFirst-degree relativesObsessive-compulsive symptomsSocioeconomic statusImportant risk factorLow socioeconomic statusFuture longitudinal studiesClinical correlatesAssessed childrenRisk factorsDegree relativesFamily historySymptomsContamination/Longitudinal studyOCD diagnosisDisordersChildrenHigh rateFamily membersChildhoodCorrelatesStatusEarly vulnerabilities for psychiatric disorders in elementary schoolchildren from four Brazilian regions
Paula C, Mari J, Bordin I, Miguel E, Fortes I, Barroso N, Rohde L, Coutinho E. Early vulnerabilities for psychiatric disorders in elementary schoolchildren from four Brazilian regions. Social Psychiatry And Psychiatric Epidemiology 2018, 53: 477-486. PMID: 29511791, DOI: 10.1007/s00127-018-1503-4.Peer-Reviewed Original Research
2017
Specific and social fears in children and adolescents: separating normative fears from problem indicators and phobias
Laporte P, Pan P, Hoffmann M, Wakschlag L, Rohde L, Miguel E, Pine D, Manfro G, Salum G. Specific and social fears in children and adolescents: separating normative fears from problem indicators and phobias. Brazilian Journal Of Psychiatry 2017, 39: 118-125. PMID: 28300935, PMCID: PMC7111439, DOI: 10.1590/1516-4446-2016-2064.Peer-Reviewed Original Research
2016
Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder: report on two cases and proposal for a randomized, sham-controlled trial
da Silva R, Brunoni A, Miguel E, Shavitt R. Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder: report on two cases and proposal for a randomized, sham-controlled trial. Sao Paulo Medical Journal 2016, 134: 446-450. PMID: 27901245, PMCID: PMC10871858, DOI: 10.1590/1516-3180.2016.0155010716.Peer-Reviewed Original ResearchConceptsTreatment-resistant obsessive-compulsive disorderTranscranial direct current stimulationObsessive-compulsive disorderDirect current stimulationClinical trialsCurrent stimulationSham-controlled trialSerotonin reuptake inhibitorsSupplementary motor cortexPrimary obsessive-compulsive disorderCognitive behavioral therapySecondary outcomesPrimary outcomeReuptake inhibitorsSham interventionFirst patientCortical excitabilityMotor cortexUniversity HospitalWeek 4YBOCS scoresNeuromodulation techniquesNon-invasive techniqueBrain circuitsPatientsAssociation of serum interleukin-6 with mental health problems in children exposed to perinatal complications and social disadvantage
Mansur R, Cunha G, Asevedo E, Zugman A, Rizzo L, Grassi-Oliveira R, Levandowski M, Gadelha A, Pan P, Teixeira A, McIntyre R, Mari J, Rohde L, Miguel E, Bressan R, Brietzke E. Association of serum interleukin-6 with mental health problems in children exposed to perinatal complications and social disadvantage. Psychoneuroendocrinology 2016, 71: 94-101. PMID: 27258821, DOI: 10.1016/j.psyneuen.2016.05.015.Peer-Reviewed Original ResearchMeSH KeywordsChildCohort StudiesFamily CharacteristicsFemaleHumansInterleukin-6MaleMental DisordersMental HealthPerinatal CareRisk FactorsSocioeconomic FactorsSurveys and QuestionnairesConceptsParental mood disorderMental health problemsSerum interleukin-6Interleukin-6Perinatal complicationsEnvironmental risk factorsHealth problemsRisk factorsSerum levelsPsychiatric diagnosisParents' psychiatric diagnosisHigher serum levelsHigh Risk Cohort StudyMultiple risk factorsSocial disadvantageCohort studySystemic inflammationSocio-demographic characteristicsInflammatory activationMood disordersPsychiatric disordersDisorder pathogenesisComplicationsFamilial riskCumulative risk modelMeasuring child maltreatment using multi-informant survey data: a higher-order confirmatory factor analysis
Salum G, DeSousa D, Manfro G, Pan P, Gadelha A, Brietzke E, Miguel E, Mari J, do Rosário M, Grassi-Oliveira R. Measuring child maltreatment using multi-informant survey data: a higher-order confirmatory factor analysis. Trends In Psychiatry And Psychotherapy 2016, 38: 23-32. PMID: 27007940, DOI: 10.1590/2237-6089-2015-0036.Peer-Reviewed Original ResearchConceptsConfirmatory factor analysisChild maltreatmentOppositional defiant disorder/conduct disorderAttention deficit hyperactivity disorderHigher-order confirmatory factor analysisMulti-informant approachDeficit hyperactivity disorderLower-order factorsLarge community sampleMulti-informant survey dataHigher-order factorsFactor analysisMeasures of psychopathologyTeacher-reported scoresOverall child maltreatmentFear disordersProsocial measuresHyperactivity disorderBrief measureDistress disordersCommunity sampleConduct disorderEmotional abuseDivergent validitySexual abuse
2015
Prevalence of psychiatric disorders among children and adolescents from four Brazilian regions
Paula C, Coutinho E, Mari J, Rohde L, Miguel E, Bordin I. Prevalence of psychiatric disorders among children and adolescents from four Brazilian regions. Brazilian Journal Of Psychiatry 2015, 37: 178-179. PMID: 26083816, DOI: 10.1590/1516-4446-2014-1606.Peer-Reviewed Original ResearchAdolescentBrazilChildCross-Sectional StudiesHumansMental DisordersMental HealthPrevalenceSurveys and Questionnaires
2014
High risk cohort study for psychiatric disorders in childhood: rationale, design, methods and preliminary results
Salum G, Gadelha A, Pan P, Moriyama T, Graeff‐Martins A, Tamanaha A, Alvarenga P, Krieger F, Fleitlich‐Bilyk B, Jackowski A, Sato J, Brietzke E, Polanczyk G, Brentani H, de Jesus Mari J, Do Rosário M, Manfro G, Bressan R, Mercadante M, Miguel E, Rohde L. High risk cohort study for psychiatric disorders in childhood: rationale, design, methods and preliminary results. International Journal Of Methods In Psychiatric Research 2014, 24: 58-73. PMID: 25469819, PMCID: PMC6878239, DOI: 10.1002/mpr.1459.Peer-Reviewed Original ResearchConceptsHigh Risk Cohort StudyMental disordersCohort studyPsychiatric disordersHigh-risk stratumChild mental disordersChildhood psychiatric disordersUseful clinical informationDiagnostic instrumentHigh riskClinical informationScreening instrumentFamily psychopathologyDisordersBaseline phaseScreening procedureChild psychiatryChildrenParticipation ratesPreliminary resultsPrevalenceStudyFamily ratesA randomised controlled trial of a web-based educational program in child mental health for schoolteachers
Pereira C, Wen C, Miguel E, Polanczyk G. A randomised controlled trial of a web-based educational program in child mental health for schoolteachers. European Child & Adolescent Psychiatry 2014, 24: 931-940. PMID: 25395381, DOI: 10.1007/s00787-014-0642-8.Peer-Reviewed Original ResearchConceptsWaiting-list control groupMental disordersChild mental healthControl groupWeb-based programMental healthChild mental disordersWaiting list groupProgram interventionsWeb-based educational programMiddle-income countriesTreat approachIntervention groupDisordersEducational programsInterventionVideo groupTrialsCommunity resourcesFuture studiesGroupComplete casesHealthWeeks
2012
‘Impulsive compulsivity’ in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome
Kashyap H, Fontenelle L, Miguel E, Ferrão Y, Torres A, Shavitt R, Ferreira-Garcia R, do Rosário M, Yücel M. ‘Impulsive compulsivity’ in obsessive-compulsive disorder: A phenotypic marker of patients with poor clinical outcome. Journal Of Psychiatric Research 2012, 46: 1146-1152. PMID: 22647523, DOI: 10.1016/j.jpsychires.2012.04.022.Peer-Reviewed Original Research
2011
Suicidality in obsessive-compulsive disorder: prevalence and relation to symptom dimensions and comorbid conditions.
Torres A, Ramos-Cerqueira A, Ferrão Y, Fontenelle L, do Rosário M, Miguel E. Suicidality in obsessive-compulsive disorder: prevalence and relation to symptom dimensions and comorbid conditions. The Journal Of Clinical Psychiatry 2011, 72: 17-26; quiz 119-20. PMID: 21272513, DOI: 10.4088/jcp.09m05651blu.Peer-Reviewed Original ResearchMeSH KeywordsAdultComorbidityCross-Sectional StudiesDepressive Disorder, MajorDisruptive, Impulse Control, and Conduct DisordersFemaleHumansLongitudinal StudiesMaleObsessive-Compulsive DisorderPersonality InventoryPrevalenceReligion and PsychologyRisk FactorsSexual BehaviorStress Disorders, Post-TraumaticSuicideSuicide, AttemptedSurveys and QuestionnairesConceptsPosttraumatic stress disorderMajor depressive disorderObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleCurrent suicidal thoughtsSubstance use disordersImpulse control disordersSuicidal thoughtsObsessive Compulsive ScaleDepressive disorderUse disordersDSM-IV Axis I DisordersSuicidal behaviorComorbid substance use disorderCompulsive ScaleOCD patientsLifetime major depressive disorderCross-sectional studyStructured Clinical InterviewAxis I DisordersLogistic regression analysisPrimary obsessive-compulsive disorderSymptom dimensionsLifetime suicidal thoughtsBrazilian Research Consortium
2010
Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features
Conrado L, Hounie A, Diniz J, Fossaluza V, Torres A, Miguel E, Rivitti E. Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features. Journal Of The American Academy Of Dermatology 2010, 63: 235-243. PMID: 20561712, DOI: 10.1016/j.jaad.2009.09.017.Peer-Reviewed Original ResearchConceptsBody dysmorphic disorderCosmetic groupClinical characteristicsDermatologic patientsDermatologic treatmentPrevalence of BDDDysmorphic disorderGeneral dermatology patientsCross-sectional studyMental health professionalsCosmetic settingsDermatology settingsClinical featuresPrevious diagnosisDermatology patientsControl subjectsUniversity HospitalDermatologic settingDermatology groupCurrent prevalencePatientsControl groupHealth professionalsPsychiatric conditionsRetrospective data
2008
Sex differences in the phenotypic expression of obsessive-compulsive disorder: an exploratory study from Brazil
Torresan R, de Abreu Ramos-Cerqueira A, de Mathis M, Diniz J, Ferrão Y, Miguel E, Torres A. Sex differences in the phenotypic expression of obsessive-compulsive disorder: an exploratory study from Brazil. Comprehensive Psychiatry 2008, 50: 63-69. PMID: 19059516, DOI: 10.1016/j.comppsych.2008.05.005.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderObsessive-compulsive symptomsBeck DepressionYale Global Tic Severity ScaleComorbid simple phobiasFemale Brazilian patientsStructured Clinical InterviewPrivate practice clinicTic Severity ScaleAnxiety InventoryComorbid tic disordersEfficacious treatment approachGlobal symptom severityPosttraumatic stress disorderSex-related differencesYale-Brown ObsessiveClinical characteristicsClinical featuresMean agePsychiatric comorbiditySymptom interferencePractice clinicsTic disordersBrazilian patientsFamily history
2006
Prenatal, Perinatal, and Postnatal Risk Factors in Obsessive–Compulsive Disorder
Vasconcelos M, Sampaio A, Hounie A, Akkerman F, Curi M, Lopes A, Miguel E. Prenatal, Perinatal, and Postnatal Risk Factors in Obsessive–Compulsive Disorder. Biological Psychiatry 2006, 61: 301-307. PMID: 17123475, DOI: 10.1016/j.biopsych.2006.07.014.Peer-Reviewed Original ResearchConceptsPostnatal risk factorsObsessive-compulsive disorderRisk factorsProlonged laborOCD patientsExcessive weight gainLogistic regression analysisEarly risk factorsHyperemesis gravidarumPreterm birthPrenatal careControl subjectsStandardized questionnaireControl groupWeight gainEdemaSocioeconomic classCompulsive disorderPregnancyPatientsRegression analysisGestationPerinatalGreater frequencyEnvironmental factors