2022
Utilisation and costs of mental health-related service use among adolescents
Ziebold C, Silva-Ribeiro W, King D, McDaid D, Hoffmann M, Romeo R, Pan P, Miguel E, Bressan R, Rohde L, Salum G, de Jesus Mari J, Evans-Lacko S. Utilisation and costs of mental health-related service use among adolescents. PLOS ONE 2022, 17: e0273628. PMID: 36084089, PMCID: PMC9462733, DOI: 10.1371/journal.pone.0273628.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentHumansMental DisordersMental HealthMental Health ServicesProspective StudiesSocial StigmaConceptsService useMental illnessParental stigmaSocial care service useTrajectories of psychopathologyCare service useProspective community cohortMental health conditionsMental health problemsMiddle-income countriesAverage annual costService utilisationCommunity cohortHigher oddsPsychiatric disordersCare needsWhite ethnicityMental health-related service useHealth problemsStigmatising attitudesPsychiatric conditionsMental disordersLogistic regressionHealth conditionsMental healthChronic lung lesions in COVID-19 survivors: predictive clinical model
Carvalho C, Chate R, Sawamura M, Garcia M, Lamas C, Cardenas D, Lima D, Scudeller P, Salge J, Nomura C, Gutierrez M, Araújo A, Segurado A, Montal A, Miethke-Morais A, Levin A, Perondi B, Guedes B, Carmo C, Lázari C, Antonio C, Tanaka C, Leite C, Gomes C, Utiyama E, Burdmann E, Bonfá E, Kallas E, Sabino E, Miguel E, Pinna F, Kawano F, Busatto G, Cerri G, Fonseca G, Souza H, Marcilio I, Rios I, Hallak J, Krieger J, Ferreira J, Marchini J, Oliveira L, Harima L, Batisttella L, Yu L, Castro L, Rocha M, Magri M, Mancini M, de Jesus M, Corrêa M, Francisco M, Rossi M, Silva M, Imamura M, Oliveira M, Gouveia N, Forlenza O, Lotufo P, Bento R, Nitrini R, Damiano R, Chammas R, Francisco R, Fusco S, Barros-Filho T, Mauad T, Guimarães T, Avelino-Silva T, Filho W. Chronic lung lesions in COVID-19 survivors: predictive clinical model. BMJ Open 2022, 12: e059110. PMID: 35697456, PMCID: PMC9195157, DOI: 10.1136/bmjopen-2021-059110.Peer-Reviewed Original ResearchConceptsChest X-rayPredictive clinical modelCOVID-19 survivorsLung lesionsClinical modelLung lesion detectionMMRC scaleChest CTMedical Research Council dyspnoea scaleSARS-CoV-2-infected patientsSARS-CoV-2 infectionCOVID-19 sequelaeSignificant pulmonary abnormalitiesProspective cohort studyGround-glass opacitiesCOVID-19 infectionChronic lung lesionsLesion detectionDyspnoea scalePulmonary involvementTraction bronchiectasisCohort studyCXR findingsHospital dischargePulmonary function
2021
Childhood poverty and mental health disorders in early adulthood: evidence from a Brazilian cohort study
Ziebold C, Evans-Lacko S, Andrade M, Hoffmann M, Fonseca L, Barbosa M, Pan P, Miguel E, Bressan R, Rohde L, Salum G, Schafer J, de Jesus Mari J, Gadelha A. Childhood poverty and mental health disorders in early adulthood: evidence from a Brazilian cohort study. European Child & Adolescent Psychiatry 2021, 32: 903-914. PMID: 34853911, DOI: 10.1007/s00787-021-01923-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrazilChild PovertyCohort StudiesFemaleHumansMental DisordersMental HealthProspective StudiesStress, PsychologicalConceptsMental health disordersStressful life eventsEarly adulthoodHealth disordersPreventable risk factorsDifferent stressful life eventsInternalizing disordersBrazilian cohort studyProspective community cohortWell-Being AssessmentCohort studyCommunity cohortRisk factorsStratified analysisPsychiatric diagnosisExternalizing disordersChildhood povertyDisordersBaselineAdulthoodStandardized classificationHigh exposureLife eventsAssociationYoung peopleLongitudinal associations between positive attributes and psychopathology and their interactive effects on educational outcomes
Romani-Sponchiado A, Vidal-Ribas P, Bressan R, de Jesus Mari J, Miguel E, Gadelha A, Rohde L, Evans-Lacko S, Salum G, Hoffmann M. Longitudinal associations between positive attributes and psychopathology and their interactive effects on educational outcomes. European Child & Adolescent Psychiatry 2021, 32: 463-474. PMID: 34559317, DOI: 10.1007/s00787-021-01882-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChild, PreschoolEducational StatusFemaleHumansMaleMental DisordersProspective StudiesPsychopathologySchoolsConceptsEducational outcomesSchool dropoutCross-lagged panel modelBetter educational outcomesLow literacy abilityPositive attributesLiteracy abilitiesLongitudinal impactGeneral factorDropoutConduct symptomsSchoolingLiteracyLearningConduct problemsYouthConstructsOutcomesPanel modelLongitudinal associationsAttributes
2019
Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders
Carvalho C, Pan P, Ota V, Spindola L, Xavier G, Santoro M, Mazzotti D, Pellegrino R, Hakonarson H, Rohde L, Miguel E, Gadelha A, Bressan R, Belangero S. Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders. Psychiatry Research 2019, 273: 575-577. PMID: 30716596, DOI: 10.1016/j.psychres.2019.01.078.Peer-Reviewed Original ResearchConceptsMental disordersSingle nucleotide polymorphismsSchool-based prospective studyAdolescent psychiatric disordersBonferroni multiple comparison correctionChild maltreatmentProspective studyPsychiatric disordersMultiple comparison correctionSignificant associationGenetic factorsDisordersNucleotide polymorphismsPsychopathologyLogistic modelMaltreatment
2018
Associations between children’s family environment, spontaneous brain oscillations, and emotional and behavioral problems
Sato J, Biazoli C, Salum G, Gadelha A, Crossley N, Vieira G, Zugman A, Picon F, Pan P, Hoexter M, Amaro E, Anés M, Moura L, Del’Aquilla M, Mcguire P, Rohde L, Miguel E, Bressan R, Jackowski A. Associations between children’s family environment, spontaneous brain oscillations, and emotional and behavioral problems. European Child & Adolescent Psychiatry 2018, 28: 835-845. PMID: 30392120, DOI: 10.1007/s00787-018-1240-y.Peer-Reviewed Original ResearchConceptsFamily environmentMental health outcomesFamily coherenceEmotional problemsOrbitofrontal cortexTemporal poleResting-state fMRI dataLeft temporal poleSpontaneous brain oscillationsChild's family environmentRight orbitofrontal cortexOscillatory neural activityHealth outcomesBrain oscillationsBehavioral problemsNeural activityFMRI dataFMRI metricsBrain areasLow-frequency fluctuationsFractional amplitudeLower incidenceSpontaneous activityHigh incidenceExploratory study
2016
International prescribing practices in obsessive–compulsive disorder (OCD)
Brakoulias V, Starcevic V, Belloch A, Dell'Osso L, Ferrão Y, Fontenelle L, Lochner C, Marazziti D, Martin A, Matsunaga H, Miguel E, Reddy Y, do Rosário M, Shavitt R, Sundar A, Stein D, Viswasam K. International prescribing practices in obsessive–compulsive disorder (OCD). Human Psychopharmacology Clinical And Experimental 2016, 31: 319-324. PMID: 27271200, DOI: 10.1002/hup.2541.Peer-Reviewed Original Research
2013
The impact of comorbid body dysmorphic disorder on the response to sequential pharmacological trials for obsessive-compulsive disorder
Diniz J, Costa D, Cassab R, Pereira C, Miguel E, Shavitt R. The impact of comorbid body dysmorphic disorder on the response to sequential pharmacological trials for obsessive-compulsive disorder. Journal Of Psychopharmacology 2013, 28: 603-611. PMID: 24288238, DOI: 10.1177/0269881113512042.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive Agents, Second-GenerationAntidepressive Agents, TricyclicAntipsychotic AgentsBody Dysmorphic DisordersBrazilClomipramineComorbidityDrug Therapy, CombinationFemaleFluoxetineHumansMaleObsessive-Compulsive DisorderProspective StudiesQuetiapine FumarateRisk FactorsTreatment OutcomeConceptsBody dysmorphic disorderComorbid body dysmorphic disorderPharmacological trialsDysmorphic disorderAdult obsessive-compulsive disorder (OCD) patientsSequential treatment strategyObsessive-compulsive disorder patientsSequential treatmentFluoxetine monotherapyClinical characteristicsObsessive-compulsive disorderInitial severityTreatment strategiesDisorder patientsTreatment groupsPatientsWorse responseBDD patientsEffects of sexGEE modelTrialsDisordersSequential trialsWeeksType of augmentation
2012
Does anti-obsessional pharmacotherapy treat so-called comorbid depressive and anxiety states?
Valerio C, Diniz J, Fossaluza V, de Mathis M, Belotto-Silva C, Joaquim M, Filho E, Shavitt R. Does anti-obsessional pharmacotherapy treat so-called comorbid depressive and anxiety states? Journal Of Affective Disorders 2012, 139: 187-192. PMID: 22455835, DOI: 10.1016/j.jad.2012.02.002.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderPsychiatric comorbidityTreatment responseOCD treatment responseTic disordersOCD treatmentAnxiety disordersOCD patientsNon-blinded studyAdditional psychiatric disordersCertain comorbid disordersPrimary obsessive-compulsive disorderCommon comorbiditiesAdult patientsComorbid conditionsComorbid depressiveChronic conditionsMajor depressionTreatment protocolComorbiditiesComorbid disordersPsychiatric disordersDisorders ProgramConventional treatmentPossible association
2009
Treatment of Resistant Obsessive-Compulsive Disorder With Ventral CapsularVentral Striatal Gamma Capsulotomy: A Pilot Prospective Study
Lopes A, Greenberg B, Norén G, Canteras M, Busatto G, de Mathis M, Taub A, D'Alcante C, Hoexter M, Gouvea F, Cecconi J, Gentil A, Ferrão Y, Fuentes D, de Castro C, Leite C, Salvajoli J, Duran F, Rasmussen S, Miguel E. Treatment of Resistant Obsessive-Compulsive Disorder With Ventral CapsularVentral Striatal Gamma Capsulotomy: A Pilot Prospective Study. Journal Of Neuropsychiatry 2009, 21: 381-392. PMID: 19996246, DOI: 10.1176/jnp.2009.21.4.381.Peer-Reviewed Original ResearchConceptsResistant obsessive-compulsive disorderRefractory OCD patientsAdverse effectsPilot prospective studyObsessive-compulsive disorder patientsAdverse eventsProspective studyObsessive-compulsive disorderStereotactic radiosurgeryDepressive symptomsDisorder patientsSide effectsConventional treatmentCapsulotomyTherapeutic promisePatientsOCD patientsTreatmentSurgeryRadiosurgerySymptomsMonths
2008
Gamma ventral capsulotomy for treatment of resistant obsessive-compulsive disorder: A structural MRI pilot prospective study
Cecconi J, Lopes A, de Souza Duran F, Santos L, Hoexter M, Gentil A, Canteras M, de Castro C, Norén G, Greenberg B, Rauch S, Busatto G, Miguel E. Gamma ventral capsulotomy for treatment of resistant obsessive-compulsive disorder: A structural MRI pilot prospective study. Neuroscience Letters 2008, 447: 138-142. PMID: 18835422, DOI: 10.1016/j.neulet.2008.09.061.Peer-Reviewed Original ResearchConceptsGamma ventral capsulotomyObsessive-compulsive disorderRefractory obsessive-compulsive disorderResistant obsessive-compulsive disorderRefractory OCD patientsYear of radiosurgeryPilot prospective studyVoxel-based morphometry methodRegional structural abnormalitiesGray matter volumeRight inferior frontal gyrusInferior orbitofrontal cortexPostoperative increaseProspective studyInferior frontal gyrusMagnetic resonance imaging dataMatter volumeMRI scansNeurobiological changesStructural abnormalitiesOrbitofrontal cortexCapsulotomyPatientsOCD patientsFrontal gyrus
1990
Psychic changes in systemic lupus erythematosus: a multidisciplinary prospective study.
Miguel Filho E, Pereira R, Busatto Filho G, Shavitt R, Hirsch R, de Sá L, de Arruda P. Psychic changes in systemic lupus erythematosus: a multidisciplinary prospective study. Revista Da Associação Médica Brasileira 1990, 36: 83-90. PMID: 1965671.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCentral Nervous SystemFemaleHumansLupus Erythematosus, SystemicNeurocognitive DisordersProspective StudiesConceptsProspective studyAnti-Ro/SSNervous system involvementCerebrospinal fluid analysisOrganic mental syndromeSystemic lupus erythematosusMultidisciplinary approachAnti-U1 RNPMultidisciplinary prospective studyAdequate control groupsAnti-nDNALupus patientsNeurologic findingsLupus erythematosusLaboratory findingsMental syndromesSystem involvementHigh prevalenceOphthalmologic alterationsPsychic alterationsElevated proteinPrimary manifestationCognitive symptomsControl groupPsychic symptoms