2019
Transcranial direct current stimulation for Obsessive-Compulsive Disorder: patient selection and perspectives
da Silva R, Brunoni A, Miguel E, Shavitt R. Transcranial direct current stimulation for Obsessive-Compulsive Disorder: patient selection and perspectives. Neuropsychiatric Disease And Treatment 2019, 15: 2663-2669. PMID: 31571882, PMCID: PMC6754675, DOI: 10.2147/ndt.s184839.Peer-Reviewed Original ResearchTranscranial direct current stimulationDirect current stimulationSevere obsessive-compulsive disorderObsessive-compulsive disorderCurrent stimulationPrevious conventional treatmentSafe tolerability profileFirst treatment optionImprovement of OCDModalities of treatmentNon-invasive neuromodulation techniqueAlternative treatment modalityPubMed/MEDLINETime of assessmentTolerability profileClinical characteristicsClinical presentationPatient selectionPsychiatric comorbidityPharmacological treatmentTreatment optionsTreatment modalitiesClinical severityNeuromodulation techniquesConventional treatment
2012
CLINICAL PREDICTORS OF LONG‐TERM OUTCOME IN OBSESSIVE‐COMPULSIVE DISORDER
Jakubovski E, Diniz J, Valerio C, Fossaluza V, Belotto‐Silva C, Gorenstein C, Miguel E, Shavitt R. CLINICAL PREDICTORS OF LONG‐TERM OUTCOME IN OBSESSIVE‐COMPULSIVE DISORDER. Depression And Anxiety 2012, 30: 763-772. PMID: 23109056, DOI: 10.1002/da.22013.Peer-Reviewed Original ResearchConceptsLong-term outcomesObsessive-compulsive disorderPositive family historyGroup cognitive behavioral therapyDepressive disorderFamily historyOCD patientsOnset of OCDInitial treatment modalityComorbid psychiatric disordersPercent of subjectsBeck depression scoresDuration of OCDCognitive behavioral therapyYale-Brown ObsessiveUntreated patientsClinical factorsClinical predictorsInitial treatmentOpen trialWorse prognosisClinical variablesPharmacological treatmentPsychiatric comorbidityTreatment modalities
2011
Risk factors for early treatment discontinuation in patients with obsessive-compulsive disorder
Diniz J, Malavazzi D, Fossaluza V, Belotto-Silva C, Borcato S, Pimentel I, Miguel E, Shavitt R. Risk factors for early treatment discontinuation in patients with obsessive-compulsive disorder. Clinics 2011, 66: 387-393. PMID: 21552660, PMCID: PMC3071996, DOI: 10.1590/s1807-59322011000300004.Peer-Reviewed Original ResearchConceptsEarly treatment discontinuationSelective serotonin reuptake inhibitorsTreatment discontinuationObsessive-compulsive disorder patientsObsessive-compulsive disorderDisorder patientsFirst-line treatmentGroup of patientsSerotonin reuptake inhibitorsStructured Clinical InterviewLogistic regression analysisLogistic regression modelsGeneralized anxiety disorderCognitive behavioral therapyMann-Whitney testClinical characteristicsCompliant patientsDiscontinuation ratesReuptake inhibitorsPsychiatric comorbidityClinical correlatesTreatment modalitiesRisk factorsSomatization disorderDiscontinuation