2023
Cognitive impairment in long-COVID and its association with persistent dysregulation in inflammatory markers
Damiano R, de Almeida Rocca C, de Pádua Serafim A, Loftis J, Talib L, Pan P, Cunha-Neto E, Kalil J, de Castro G, Seelaender M, Guedes B, Marie S, de Souza H, Nitrini R, Miguel E, Busatto G, Forlenza O, Group H, Utiyama E, Segurado A, Perondi B, Miethke-Morais A, Montal A, Harima L, Fusco S, Silva M, Rocha M, Marcilio I, Rios I, Kawano F, de Jesus M, Kallas É, Carmo C, Tanaka C, Marchini J, Carvalho C, Ferreira J, Levin A, Oliveira M, Guimarães T, dos Santos Lázari C, da Silva Duarte A, Sabino E, Magri M, Barros-Filho T, Francisco M. Cognitive impairment in long-COVID and its association with persistent dysregulation in inflammatory markers. Frontiers In Immunology 2023, 14: 1174020. PMID: 37287969, PMCID: PMC10242059, DOI: 10.3389/fimmu.2023.1174020.Peer-Reviewed Original ResearchConceptsCognitive impairmentInflammatory markersSARS-CoV-2 infectionLong-term cognitive impairmentLong-term cognitive outcomesC-reactive proteinDisease severity markersCOVID-19 infectionCognitive performanceHospital dischargeInflammatory backgroundClinical statusD-dimerSeverity markersGeneral cognitionOverall cognitive performanceTNF-betaPhysical activityParticipants 6Severe formG-CSFPersistent dysregulationMultivariate analysisSociodemographic characteristicsCognitive deficits
2022
Obsessional slowness in obsessive-compulsive disorder: identifying characteristics and comorbidities in a clinical sample
Crowe E, Rosário M, Ferrão Y, Albertella L, Miguel E, Fontenelle L. Obsessional slowness in obsessive-compulsive disorder: identifying characteristics and comorbidities in a clinical sample. International Journal Of Psychiatry In Clinical Practice 2022, 27: 161-170. PMID: 36409661, DOI: 10.1080/13651501.2022.2147441.Peer-Reviewed Original ResearchAssociation between chemosensory impairment with neuropsychiatric morbidity in post-acute COVID-19 syndrome: results from a multidisciplinary cohort study
Damiano R, Neto D, Oliveira J, Magalhães Santos J, Alves J, Guedes B, Nitrini R, de Araújo A, Oliveira M, Brunoni A, Voegels R, Bento R, Busatto G, Miguel E, Forlenza O, de Rezende Pinna F. Association between chemosensory impairment with neuropsychiatric morbidity in post-acute COVID-19 syndrome: results from a multidisciplinary cohort study. European Archives Of Psychiatry And Clinical Neuroscience 2022, 273: 325-333. PMID: 35633395, PMCID: PMC9142732, DOI: 10.1007/s00406-022-01427-3.Peer-Reviewed Original ResearchConceptsCohort studyChemosensory impairmentPost-acute COVID-19 syndromeCOVID-19 syndromeCentral nervous systemCOVID-19SARS-CoV-2Word list memory taskEpisodic memory impairmentSmell functionAdult patientsChemosensory dysfunctionAcute phaseNeuropsychiatric symptomsNeuropsychiatric morbidityGustatory lossHospitalization dataNeuropsychiatric impairmentEligible individualsSevere formCognition dysfunctionNervous systemMemory impairmentMultivariate analysisNeuropsychiatric disordersPost-COVID-19 psychiatric and cognitive morbidity: Preliminary findings from a Brazilian cohort study
Damiano R, Caruso M, Cincoto A, de Almeida Rocca C, de Pádua Serafim A, Bacchi P, Guedes B, Brunoni A, Pan P, Nitrini R, Beach S, Fricchione G, Busatto G, Miguel E, Forlenza O, Group H. Post-COVID-19 psychiatric and cognitive morbidity: Preliminary findings from a Brazilian cohort study. General Hospital Psychiatry 2022, 75: 38-45. PMID: 35134702, PMCID: PMC8734055, DOI: 10.1016/j.genhosppsych.2022.01.002.Peer-Reviewed Original ResearchConceptsCognitive morbidityCognitive outcomesAnxiety disordersPost-traumatic stress disorderRelevant psychosocial variablesCognitive batteryMemory declineStructured psychiatric interviewStress disorderPsychosocial variablesStandardized measuresPsychosocial stressorsPsychometric testsCognitive impairmentPsychiatric interviewSevere formPreliminary findingsSARS-CoV-2 infectionCohort of survivorsLong-term outcomesAcute-phase diseaseBrazilian cohort studyCOVID-19DisordersDepression
2010
Bipolar disorder and comorbid obsessive‐compulsive disorder is associated with higher rates of anxiety and impulse control disorders
Issler C, Monkul E, Amaral J, Tamada R, Shavitt R, Miguel E, Lafer B. Bipolar disorder and comorbid obsessive‐compulsive disorder is associated with higher rates of anxiety and impulse control disorders. Acta Neuropsychiatrica 2010, 22: 81-86. PMID: 25385033, DOI: 10.1111/j.1601-5215.2010.00457.x.Peer-Reviewed Original ResearchTreatment-emergent maniaObsessive-compulsive disorderFemale BD patientsComorbid obsessive-compulsive disorderBipolar disorderControl disordersResidual symptomsDepressive episodeBD patientsOCD patientsPrevious depressive episodesStructured Clinical InterviewHigh rateClinical characteristicsDisorder burdenChronic episodesFemale outpatientsTic disordersHigh riskComorbid disordersSevere formPatientsClinical InterviewSkin pickingDSM-IV