2019
Understanding gamma ventral capsulotomy: Potential implications of diffusion tensor image tractography on target selectivity
de Oliveira Santos B, Gorgulho A, Saraiva C, Lopes A, Gomes J, Pássaro A, Hoexter M, Miguel E, De Salles A. Understanding gamma ventral capsulotomy: Potential implications of diffusion tensor image tractography on target selectivity. Surgical Neurology International 2019, 10: 136. PMID: 31528471, PMCID: PMC6744751, DOI: 10.25259/sni-65-2019.Peer-Reviewed Original ResearchDiffusion tensor image tractographyMorbid obesity patientsOCD patientsObesity patientsInternal capsuleOrbitofrontal cortexAnterior internal capsuleGamma ventral capsulotomyMedial orbitofrontal cortexFunctional stereotactic proceduresFunctional patientsMorbid obesityMean ageTract fibersAnterior limbCerebral hemispheresPatientsFiber tractsDisorder individualsStereotactic proceduresDeep brain stimulation implantsObesityTractography parametersExact topographyTractography
2017
Lateral hypothalamic activity indicates hunger and satiety states in humans
Talakoub O, Paiva R, Milosevic M, Hoexter M, Franco R, Alho E, Navarro J, Pereira J, Popovic M, Savage C, Lopes A, Alvarenga P, Damiani D, Teixeira M, Miguel E, Fonoff E, Batistuzzo M, Hamani C. Lateral hypothalamic activity indicates hunger and satiety states in humans. Annals Of Clinical And Translational Neurology 2017, 4: 897-901. PMID: 29296618, PMCID: PMC5740250, DOI: 10.1002/acn3.466.Peer-Reviewed Original ResearchDeep brain stimulationSatiety stateLateral hypothalamic activityLow gamma activityPrader-Willi patientsFood-related cuesLocal field potentialsHypothalamic activityFood intakeBrain stimulationEarly sensationPatterns of activityAlpha rhythmField potentialsObesityPatientsNeuromodulation studiesHumansSatietyIntakeActivity
2016
DBS for Obesity
Franco R, Fonoff E, Alvarenga P, Lopes A, Miguel E, Teixeira M, Damiani D, Hamani C. DBS for Obesity. Brain Sciences 2016, 6: 21. PMID: 27438859, PMCID: PMC5039450, DOI: 10.3390/brainsci6030021.Peer-Reviewed Original ResearchDeep brain stimulationMorbid obesityUse of DBSDifferent brain targetsNon-negligible incidenceNeurosurgical modalityNumerous comorbiditiesRefractory obesityBariatric surgeryOperative failureEarly mortalitySurgical resultsBrain targetsPrevalent disorderBrain stimulationSide effectsObesityNeuropsychiatric disordersDisordersComorbiditiesPatientsSurgeryBehavioral approachMortalityIncidence