2013
Can early improvement be an indicator of treatment response in obsessive-compulsive disorder? Implications for early-treatment decision-making
da Conceição Costa D, Shavitt R, Cesar R, Joaquim M, Borcato S, Valério C, Miguel E, Diniz J. Can early improvement be an indicator of treatment response in obsessive-compulsive disorder? Implications for early-treatment decision-making. Journal Of Psychiatric Research 2013, 47: 1700-1707. PMID: 23948637, DOI: 10.1016/j.jpsychires.2013.07.006.Peer-Reviewed Original ResearchConceptsBaseline Y-BOCS scoresSerotonin reuptake inhibitorsEarly improvementTreatment responseY-BOCS scoresBaseline Yale-Brown ObsessiveLogistic regressionAdequate pharmacological treatmentPotential predictive factorsWeeks of treatmentGreater reductionObsessive-compulsive disorder patientsStepwise logistic regressionWarrants further investigationYale-Brown ObsessiveClinical featuresReuptake inhibitorsObsessive-compulsive disorderPharmacological treatmentPredictive factorsMajor depressionDisorder patientsOCD treatment responseCompulsive ScaleWeeks
2012
Does anti-obsessional pharmacotherapy treat so-called comorbid depressive and anxiety states?
Valerio C, Diniz J, Fossaluza V, de Mathis M, Belotto-Silva C, Joaquim M, Filho E, Shavitt R. Does anti-obsessional pharmacotherapy treat so-called comorbid depressive and anxiety states? Journal Of Affective Disorders 2012, 139: 187-192. PMID: 22455835, DOI: 10.1016/j.jad.2012.02.002.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderPsychiatric comorbidityTreatment responseOCD treatment responseTic disordersOCD treatmentAnxiety disordersOCD patientsNon-blinded studyAdditional psychiatric disordersCertain comorbid disordersPrimary obsessive-compulsive disorderCommon comorbiditiesAdult patientsComorbid conditionsComorbid depressiveChronic conditionsMajor depressionTreatment protocolComorbiditiesComorbid disordersPsychiatric disordersDisorders ProgramConventional treatmentPossible association