2023
Brain activation during fear extinction recall in unmedicated patients with obsessive-compulsive disorder
Diniz J, Bazán P, Pereira C, Saraiva E, Ramos P, de Oliveira A, Reimer A, Hoexter M, Miguel E, Shavitt R, Batistuzzo M. Brain activation during fear extinction recall in unmedicated patients with obsessive-compulsive disorder. Psychiatry Research Neuroimaging 2023, 336: 111733. PMID: 37913655, DOI: 10.1016/j.pscychresns.2023.111733.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderExtinction recallNeutral stimuliFear conditioningFear extinction recallBlood oxygenation level-dependent (BOLD) responseFear conditioning experimentSkin conductance reactivitySpecific brain activation patternsBrain activation patternsSkin conductance responsesLevel-dependent responsesEntire sampleDACC activationUnmedicated adult patientsFear responsesBrain activationAversive stimuliLingual gyrusUnmedicated samplesActivation patternsHealthy participantsRecallOpercular cortexInsular cortex
2020
Attentional Bias in specific symmetry and cleaning dimensions of obsessive-compulsive disorder
De Mathis M, Batistuzzo M, Bar-Haim Y, Abend R, Miguel E, Morais I, Requena G, Salum G, Shavitt R. Attentional Bias in specific symmetry and cleaning dimensions of obsessive-compulsive disorder. Journal Of Anxiety Disorders 2020, 73: 102238. PMID: 32447225, DOI: 10.1016/j.janxdis.2020.102238.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderAttentional biasAB scoresComputerized dot-probe taskSymptoms of OCDDot-probe taskAllocation of attentionThreat stimuliNeutral stimuliTask conditionsOCD dimensionsOCD patientsDemographic variablesStimuliPositive interactionsNeutral conditionsMixed-effects modelsHealthy controlsIQDisordersBiasTaskScoresSymptomsPicture