2019
Transcranial direct current stimulation for Obsessive-Compulsive Disorder: patient selection and perspectives
da Silva R, Brunoni A, Miguel E, Shavitt R. Transcranial direct current stimulation for Obsessive-Compulsive Disorder: patient selection and perspectives. Neuropsychiatric Disease And Treatment 2019, 15: 2663-2669. PMID: 31571882, PMCID: PMC6754675, DOI: 10.2147/ndt.s184839.Peer-Reviewed Original ResearchTranscranial direct current stimulationDirect current stimulationSevere obsessive-compulsive disorderObsessive-compulsive disorderCurrent stimulationPrevious conventional treatmentSafe tolerability profileFirst treatment optionImprovement of OCDModalities of treatmentNon-invasive neuromodulation techniqueAlternative treatment modalityPubMed/MEDLINETime of assessmentTolerability profileClinical characteristicsClinical presentationPatient selectionPsychiatric comorbidityPharmacological treatmentTreatment optionsTreatment modalitiesClinical severityNeuromodulation techniquesConventional treatment
2016
Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder: report on two cases and proposal for a randomized, sham-controlled trial
da Silva R, Brunoni A, Miguel E, Shavitt R. Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder: report on two cases and proposal for a randomized, sham-controlled trial. Sao Paulo Medical Journal 2016, 134: 446-450. PMID: 27901245, PMCID: PMC10871858, DOI: 10.1590/1516-3180.2016.0155010716.Peer-Reviewed Original ResearchConceptsTreatment-resistant obsessive-compulsive disorderTranscranial direct current stimulationObsessive-compulsive disorderDirect current stimulationClinical trialsCurrent stimulationSham-controlled trialSerotonin reuptake inhibitorsSupplementary motor cortexPrimary obsessive-compulsive disorderCognitive behavioral therapySecondary outcomesPrimary outcomeReuptake inhibitorsSham interventionFirst patientCortical excitabilityMotor cortexUniversity HospitalWeek 4YBOCS scoresNeuromodulation techniquesNon-invasive techniqueBrain circuitsPatients
2015
Transcranial direct current stimulation in obsessive–compulsive disorder: emerging clinical evidence and considerations for optimal montage of electrodes
Senço N, Huang Y, D’Urso G, Parra L, Bikson M, Mantovani A, Shavitt R, Hoexter M, Miguel E, Brunoni A. Transcranial direct current stimulation in obsessive–compulsive disorder: emerging clinical evidence and considerations for optimal montage of electrodes. Expert Review Of Medical Devices 2015, 12: 381-391. PMID: 25982412, PMCID: PMC5777161, DOI: 10.1586/17434440.2015.1037832.Peer-Reviewed Original ResearchConceptsTranscranial direct current stimulationDirect current stimulationSystematic reviewCurrent stimulationPotential new treatmentPre-supplementary motor areaPubMed/MEDLINEObsessive-compulsive disorder (OCD) treatmentDeep brain stimulation trialsClinical evidenceObsessive-compulsive disorderStimulation trialsDBS trialsMotor areaRTMS targetsMagnetic stimulationEligibility criteriaNeuromodulation techniquesStimulation targetsDisorder treatmentNew treatmentsBrain circuitsDifferent electrode montagesTDCS montageTrials