Caudate volume differences among treatment responders, non-responders and controls in children with obsessive–compulsive disorder
Vattimo E, Barros V, Requena G, Sato J, Fatori D, Miguel E, Shavitt R, Hoexter M, Batistuzzo M. Caudate volume differences among treatment responders, non-responders and controls in children with obsessive–compulsive disorder. European Child & Adolescent Psychiatry 2019, 28: 1607-1617. PMID: 30972581, DOI: 10.1007/s00787-019-01320-w.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderGroup cognitive behavioral therapyPediatric obsessive-compulsive disorderRight caudateTreatment responseCognitive behavioral therapyCaudate nucleusPossible neural substrateTreatment respondersGM volumeStructural magnetic resonance imagingNeural substratesPrevious evidenceNeurobiological underpinningsOrbitofrontal cortexAge-matched controlsTotal GM volumeMagnetic resonance imagingBrain structuresResonance imagingChildrenRespondersBonferroni correctionCaudatePatients