2022
Associations between Family Functioning and Maternal Behavior on Default Mode Network Connectivity in School-Age Children
Rebello K, Moura L, Bueno A, Picon F, Pan P, Gadelha A, Miguel E, Bressan R, Rohde L, Sato J. Associations between Family Functioning and Maternal Behavior on Default Mode Network Connectivity in School-Age Children. International Journal Of Environmental Research And Public Health 2022, 19: 6055. PMID: 35627592, PMCID: PMC9141331, DOI: 10.3390/ijerph19106055.Peer-Reviewed Original ResearchConceptsDefault mode networkFamily Environment ScaleSchool-aged childrenPosterior cingulate cortexMedial prefrontal cortexFamily environmentFunctional connectivityDMN functional connectivityCohesive familiesMaternal behaviorDefault mode network connectivityFunctional magnetic resonance imaging (fMRI) dataEarly child experiencesPositive maternal behaviorParent-child relationshipMode network connectivityBrain functional connectivityChild affectFamily functioningMaternal overprotectionEarly adolescenceFamily cohesivenessMode networkPrefrontal cortexFamily context
2019
Association between spontaneous activity of the default mode network hubs and leukocyte telomere length in late childhood and early adolescence
Rebello K, Moura L, Xavier G, Spindola L, Carvalho C, Hoexter M, Gadelha A, Picon F, Pan P, Zugman A, Grassi-Oliveira R, Brietzke E, Belangero S, Salum G, Rohde L, Miguel E, Bressan R, Jackowski A, Sato J. Association between spontaneous activity of the default mode network hubs and leukocyte telomere length in late childhood and early adolescence. Journal Of Psychosomatic Research 2019, 127: 109864. PMID: 31706071, DOI: 10.1016/j.jpsychores.2019.109864.Peer-Reviewed Original ResearchConceptsAdverse childhood experiencesMedial prefrontal cortexPosterior cingulate cortexDefault mode networkResting-state functional magnetic resonanceEarly life stressBrain's default mode networkFunctional magnetic resonanceBlood samplesSpontaneous activityDefault mode network hubCingulate cortexDMN hubsPsychiatric conditionsFamily environmentLength shorteningPrefrontal cortexMental healthFractional amplitudeLow-frequency fluctuationsMode networkFamily Environment ScaleHypothesis-driven studiesTelomere lengthLate childhood
2016
Connectome hubs at resting state in children and adolescents: Reproducibility and psychopathological correlation
Sato J, Biazoli C, Salum G, Gadelha A, Crossley N, Vieira G, Zugman A, Picon F, Pan P, Hoexter M, Anés M, Moura L, Del’Aquilla M, Amaro E, Mcguire P, Rohde L, Miguel E, Bressan R, Jackowski A. Connectome hubs at resting state in children and adolescents: Reproducibility and psychopathological correlation. Developmental Cognitive Neuroscience 2016, 20: 2-11. PMID: 27288820, PMCID: PMC6987719, DOI: 10.1016/j.dcn.2016.05.002.Peer-Reviewed Original ResearchConceptsAnterior medial prefrontal cortexPsychiatric symptomsLarge-scale functional networksBrain hubsMental disordersHub regionsMedial prefrontal cortexResting-state fMRIFunctional cortical networksIndependent population-based samplesRight IPSPopulation-based sampleIntraparietal sulcusBrain networksPrefrontal cortexCortical networksIntegrative regionsFunctional networksAdolescentsLow centralitySymptomsChildrenDisordersReplicabilityInteresting target
2012
Differential prefrontal gray matter correlates of treatment response to fluoxetine or cognitive-behavioral therapy in obsessive–compulsive disorder
Hoexter M, Dougherty D, Shavitt R, D'Alcante C, Duran F, Lopes A, Diniz J, Batistuzzo M, Evans K, Bressan R, Busatto G, Miguel E. Differential prefrontal gray matter correlates of treatment response to fluoxetine or cognitive-behavioral therapy in obsessive–compulsive disorder. European Neuropsychopharmacology 2012, 23: 569-580. PMID: 22841131, DOI: 10.1016/j.euroneuro.2012.06.014.Peer-Reviewed Original ResearchConceptsGray matter volumeMedial prefrontal cortexCognitive behavioral therapyObsessive-compulsive disorderTreatment responseTreatment-naïve OCD patientsTreatment groupsMagnetic resonance imagingMatter volumeOrbitofrontal cortexLateral orbitofrontal cortexSymptom improvementOCD patientsFluoxetine treatment groupTrial of fluoxetineSerotonin reuptake inhibitorsAdequate therapeutic approachStructural magnetic resonance imagingCBT treatment groupRight medial prefrontal cortexGroup-based cognitive behavioral therapyRegional gray matter volumeStructural MRI scansDistinct brain regionsYale-Brown Obsessive