2024
Post-COVID-19 condition: systemic inflammation and low functional exercise capacity
de Castro G, Gama L, Ramos A, da Silva G, de Souza Teixeira A, Cunha-Neto E, de Souza H, Marie S, Talib L, Coelho V, Kalil J, de Araujo A, Ritto A, Belon A, Santos A, Barrére A, Sawamura M, Lamas C, Baldi B, Carvalho C, Kulikowski L, Damiano R, Imamura M, Neto J, Lira F, Otoch J, Miguel E, Battistella L, Forlenza O, Busatto G, Seelaender M. Post-COVID-19 condition: systemic inflammation and low functional exercise capacity. Frontiers In Nutrition 2024, 11: 1295026. PMID: 38549752, PMCID: PMC10973152, DOI: 10.3389/fnut.2024.1295026.Peer-Reviewed Original ResearchPost-COVID-19 conditionTimed Up and Go testUp-and-go testPhysical performance testsAcute COVID-19Low handgrip strengthFollow-up assessment 6Cross-sectional studySelf-reported symptomsFollow-up assessmentQuality of lifeDiagnosing pulmonary lesionsHandgrip strengthSerum cytokine profilesSerum cytokine levelsImpact of inflammationControl groupMCP-1 levelsIL-4 concentrationMale participantsHospital dischargeSymptom questionnaireSymptom groupsFemale participantsDebilitating symptoms
2020
Maternal Parenting Electronic Diary in the Context of a Home Visit Intervention for Adolescent Mothers in an Urban Deprived Area of São Paulo, Brazil: Randomized Controlled Trial
Fatori D, Argeu A, Brentani H, Chiesa A, Fracolli L, Matijasevich A, Miguel E, Polanczyk G. Maternal Parenting Electronic Diary in the Context of a Home Visit Intervention for Adolescent Mothers in an Urban Deprived Area of São Paulo, Brazil: Randomized Controlled Trial. JMIR MHealth And UHealth 2020, 8: e13686. PMID: 32720906, PMCID: PMC7420524, DOI: 10.2196/13686.Peer-Reviewed Original ResearchConceptsWeeks of pregnancyMonths of ageCompliance rateAdolescent mothersNurse homePregnant adolescentsDeprived areasHome-visiting interventionElectronic daily diaryLow-income adolescent mothersMaternal parentingControlled TrialsMiddle-income countriesAdverse outcomesEligibility criteriaUrban deprived areasControl groupPregnancyMaternal parenting behaviorsDaily diariesElectronic diaryMonthsInterventionMothersWeeks
2018
Layer-specific reduced neuronal density in the orbitofrontal cortex of older adults with obsessive–compulsive disorder
de Oliveira K, Grinberg L, Hoexter M, Brentani H, Suemoto C, Nery F, Lima L, Alho A, Farfel J, Ferretti-Rebustini R, Leite R, Moretto A, da Silva A, Lafer B, Miguel E, Nitrini R, Jacob-Filho W, Heinsen H, Pasqualucci C. Layer-specific reduced neuronal density in the orbitofrontal cortex of older adults with obsessive–compulsive disorder. Brain Structure And Function 2018, 224: 191-203. PMID: 30298291, DOI: 10.1007/s00429-018-1752-8.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMedial orbitofrontalOrbitofrontal cortexNeuronal densityOCD casesLower neuron densityCortical-subcortical circuitryOFC abnormalitiesEfferent targetsNeuron densityClinical evaluationAnterolateral areaControl groupCognitive impairmentAutopsy serviceOrbitofrontal regionsAnteromedialOlder adultsControl casesOFC areasCortexConsistent evidenceDisordersCellular levelTotal
2014
A randomised controlled trial of a web-based educational program in child mental health for schoolteachers
Pereira C, Wen C, Miguel E, Polanczyk G. A randomised controlled trial of a web-based educational program in child mental health for schoolteachers. European Child & Adolescent Psychiatry 2014, 24: 931-940. PMID: 25395381, DOI: 10.1007/s00787-014-0642-8.Peer-Reviewed Original ResearchConceptsWaiting-list control groupMental disordersChild mental healthControl groupWeb-based programMental healthChild mental disordersWaiting list groupProgram interventionsWeb-based educational programMiddle-income countriesTreat approachIntervention groupDisordersEducational programsInterventionVideo groupTrialsCommunity resourcesFuture studiesGroupComplete casesHealthWeeks
2010
Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features
Conrado L, Hounie A, Diniz J, Fossaluza V, Torres A, Miguel E, Rivitti E. Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features. Journal Of The American Academy Of Dermatology 2010, 63: 235-243. PMID: 20561712, DOI: 10.1016/j.jaad.2009.09.017.Peer-Reviewed Original ResearchConceptsBody dysmorphic disorderCosmetic groupClinical characteristicsDermatologic patientsDermatologic treatmentPrevalence of BDDDysmorphic disorderGeneral dermatology patientsCross-sectional studyMental health professionalsCosmetic settingsDermatology settingsClinical featuresPrevious diagnosisDermatology patientsControl subjectsUniversity HospitalDermatologic settingDermatology groupCurrent prevalencePatientsControl groupHealth professionalsPsychiatric conditionsRetrospective data
2006
Prenatal, Perinatal, and Postnatal Risk Factors in Obsessive–Compulsive Disorder
Vasconcelos M, Sampaio A, Hounie A, Akkerman F, Curi M, Lopes A, Miguel E. Prenatal, Perinatal, and Postnatal Risk Factors in Obsessive–Compulsive Disorder. Biological Psychiatry 2006, 61: 301-307. PMID: 17123475, DOI: 10.1016/j.biopsych.2006.07.014.Peer-Reviewed Original ResearchConceptsPostnatal risk factorsObsessive-compulsive disorderRisk factorsProlonged laborOCD patientsExcessive weight gainLogistic regression analysisEarly risk factorsHyperemesis gravidarumPreterm birthPrenatal careControl subjectsStandardized questionnaireControl groupWeight gainEdemaSocioeconomic classCompulsive disorderPregnancyPatientsRegression analysisGestationPerinatalGreater frequencyEnvironmental factors
2003
Association analysis of the catechol‐o‐methyltransferase (COMT ), serotonin transporter (5‐HTT ) and serotonin 2A receptor (5HT2A) gene polymorphisms with obsessive‐compulsive disorder
Meira‐Lima I, Shavitt R, Miguita K, Ikenaga E, Miguel E, Vallada H. Association analysis of the catechol‐o‐methyltransferase (COMT ), serotonin transporter (5‐HTT ) and serotonin 2A receptor (5HT2A) gene polymorphisms with obsessive‐compulsive disorder. Genes Brain & Behavior 2003, 3: 75-79. PMID: 15005715, DOI: 10.1046/j.1601-1848.2003.0042.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SubstitutionCarrier ProteinsCase-Control StudiesCatechol O-MethyltransferaseFemaleGene FrequencyHumansMaleMembrane GlycoproteinsMembrane Transport ProteinsNerve Tissue ProteinsObsessive-Compulsive DisorderPolymorphism, GeneticReceptor, Serotonin, 5-HT2AReference ValuesRegulatory Sequences, Nucleic AcidSerotonin Plasma Membrane Transport ProteinsConceptsObsessive-compulsive disorderGene polymorphismsT variantOCD patientsSerotonin receptor type 2A geneSerotonin-2A receptor gene polymorphismCross-sectional studyReceptor gene polymorphismsStrong genetic factorGenetic risk factorsControl subjectsRisk factorsDopaminergic systemDisease pathogenesisControl groupSerotonin transporter genePharmacological studiesPatientsGenetic factorsGenotypic distributionPrecise mechanismSignificant differencesFurther studiesCOMT geneFrequency of alleles
1990
Psychic changes in systemic lupus erythematosus: a multidisciplinary prospective study.
Miguel Filho E, Pereira R, Busatto Filho G, Shavitt R, Hirsch R, de Sá L, de Arruda P. Psychic changes in systemic lupus erythematosus: a multidisciplinary prospective study. Revista Da Associação Médica Brasileira 1990, 36: 83-90. PMID: 1965671.Peer-Reviewed Original ResearchConceptsProspective studyAnti-Ro/SSNervous system involvementCerebrospinal fluid analysisOrganic mental syndromeSystemic lupus erythematosusMultidisciplinary approachAnti-U1 RNPMultidisciplinary prospective studyAdequate control groupsAnti-nDNALupus patientsNeurologic findingsLupus erythematosusLaboratory findingsMental syndromesSystem involvementHigh prevalenceOphthalmologic alterationsPsychic alterationsElevated proteinPrimary manifestationCognitive symptomsControl groupPsychic symptoms