2022
Threat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents
Schäfer J, McLaughlin K, Manfro G, Pan P, Rohde L, Miguel E, Simioni A, Hoffmann M, Salum G. Threat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents. Developmental Science 2022, 26: e13267. PMID: 35417607, PMCID: PMC10028496, DOI: 10.1111/desc.13267.Peer-Reviewed Original ResearchConceptsChild Behavior ChecklistExecutive functionEmotional processingChildhood adversityBrazilian High-Risk CohortForms of adversityPoor developmental outcomesAttention biasAngry facesCognitive tasksCognitive developmentDevelopmental correlatesBehavior ChecklistChild developmentDevelopmental outcomesLongitudinal associationsGeneral psychopathologyPsychopathologyAdversityLatent constructsDifferential associationsWorse performanceDistinct aspectsCognitionMeaningful influence
2020
Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents
Manfro A, Pine D, Polanczyk G, Santoro M, Smoller J, Koenen K, Mari J, Pan P, Zugman A, Schäfer J, Belangero S, Gosmann N, Simioni A, Hoexter M, Miguel E, Gadelha A, Rohde L, Salum G. Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents. Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 60: 1501-1512. PMID: 33346031, PMCID: PMC10259767, DOI: 10.1016/j.jaac.2020.11.016.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresPsychiatric diagnosisExecutive functionHigher schizophrenia polygenic risk scoresExecutive dysfunctionHigh Risk Cohort StudySmaller intracranial volumeHigher attention-deficit/hyperactivity disorderAttention-deficit/hyperactivity disorderSchizophrenia polygenic risk scoresCortical surface areaDichotomized ageCohort studyFunctional impairmentRisk scoreDomains of psychopathologyBrain regionsIntracranial volumeRelevant outcomesBrain structuresHyperactivity disorderCognitive tasksLatent class analysisLower chanceDiagnosis
2019
Relationships between childhood maltreatment, impairment in executive functions and disruptive behavior disorders in a community sample of children
Bernardes E, Manitto A, Miguel E, Pan P, Batistuzzo M, Rohde L, Polanczyk G. Relationships between childhood maltreatment, impairment in executive functions and disruptive behavior disorders in a community sample of children. European Child & Adolescent Psychiatry 2019, 29: 969-978. PMID: 31559500, DOI: 10.1007/s00787-019-01408-3.Peer-Reviewed Original ResearchConceptsDisruptive behavior disordersExecutive functionChildhood maltreatmentCognitive flexibilityEF performanceCommunity sampleBehavior disorderSchool-based sampleCognitive mechanismsCognitive tasksInhibitory controlDisruptive behaviorChild maltreatmentMaltreatmentWorse performanceMental disordersModeratorChildrenImpairmentDisordersIndependent relationshipMemoryFuture studiesAssociationTask