2022
Post-acute sequelae of SARS-CoV-2 infection: relationship of central nervous system manifestations with physical disability and systemic inflammation
Busatto G, de Araujo A, Castaldelli-Maia J, Damiano R, Imamura M, Guedes B, de Rezende Pinna F, Sawamura M, Mancini M, da Silva K, Garcia M, Sumita N, Brunoni A, da Silva Duarte A, Burdmann E, Kallas E, Cerri G, Nitrini R, Bento R, Rocha V, de Souza H, Miguel E, de Carvalho C, Forlenza O, Batistella L. Post-acute sequelae of SARS-CoV-2 infection: relationship of central nervous system manifestations with physical disability and systemic inflammation. Psychological Medicine 2022, 52: 2387-2398. PMID: 35521752, PMCID: PMC9151630, DOI: 10.1017/s0033291722001374.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionPost-acute sequelaeC-reactive proteinSystemic inflammationBlood levelsPhysical disabilityD-dimer blood levelsCentral nervous system manifestationsPersistent physical disabilityPersistent systemic inflammationNervous system manifestationsSevere COVID-19Cognitive manifestationsPoor physical performanceElevated blood levelsCoronavirus disease 2019Pattern of symptomsDifferent organ systemsExploratory factor analysisSame followSystem manifestationsD-dimerClinical manifestationsKidney dysfunctionPerson visits
2021
Post-acute sequelae of SARS-CoV-2 infection (PASC): a protocol for a multidisciplinary prospective observational evaluation of a cohort of patients surviving hospitalisation in Sao Paulo, Brazil
Busatto G, de Araújo A, da Silva Duarte A, Levin A, Guedes B, Kallas E, Pinna F, de Souza H, da Silva K, Sawamura M, Seelaender M, Imamura M, Garcia M, Forlenza O, Nitrini R, Damiano R, Rocha V, Batisttella L, de Carvalho C, Initiative O, da Costa Leite C, Gomes C, Burdmann E, Miguel E, Cerri G, Fonseca G, Hallak J, Krieger J, Yu L, Castro L, Corrêa M, Mancini M, Rossi M, Gouveia N, Lotufo P, Bento R, Chammas R, Francisco R, Mauad T, Avelino-Silva T, Filho W, Group H, Bonfá E, Utiyama E, Segurado A, Perondi B, Miethke-Morais A, Montal A, Harima L, Fusco S, Silva M, Rocha M, Marcilio I, Rios I, Kawano F, de Jesus M, Carmo C, Tanaka C, Marchini J, Ferreira J, Oliveira M, Guimarães T, dos Santos Lázari C, Sabino E, MC Magri M, Barros-Filho T, Francisco M. Post-acute sequelae of SARS-CoV-2 infection (PASC): a protocol for a multidisciplinary prospective observational evaluation of a cohort of patients surviving hospitalisation in Sao Paulo, Brazil. BMJ Open 2021, 11: e051706. PMID: 34193506, PMCID: PMC8249176, DOI: 10.1136/bmjopen-2021-051706.Peer-Reviewed Original ResearchConceptsMultidisciplinary assessmentLaboratory-confirmed COVID-19SARS-CoV-2 infectionProspective observational evaluationCohort of patientsCOVID-19 inpatientsPost-acute sequelaeProspective observational studyLarge academic health centerGreater disease severityCOVID-19Cardiopulmonary functioningMultiorgan symptomsEligible subjectsInflammatory markersPeer-reviewed journalsResearch Ethics CommitteeBlood testsClinical manifestationsMuscle ultrasoundOlfactory statusHealth centersObservational studyDisease featuresPathophysiological investigations
2013
2711 – Trajectory of comorbidity in obsessive-compulsive disorder
de Mathis A, Diniz J, Shavitt R, do Rosário M, Miguel E. 2711 – Trajectory of comorbidity in obsessive-compulsive disorder. European Psychiatry 2013, 28: 1. DOI: 10.1016/s0924-9338(13)77321-8.Peer-Reviewed Original ResearchComorbid psychiatric disordersFirst diagnosisPsychiatric disordersOCD patientsAnxiety disordersMain psychiatric diagnosisPost-traumatic stress disorderClinical manifestationsComorbid schizophreniaMean ageObsessive-compulsive disorderTic disordersSeparation anxiety disorderSomatoform disordersComorbid disordersPsychiatric diagnosisPanic disorderPatientsSubstance abuseSimple phobiaStress disorderHigh frequencyOCD outpatientsDiagnosisDisorders
2006
Tourette's Syndrome
Shavitt R, Hounie A, Campos M, Miguel E. Tourette's Syndrome. Psychiatric Clinics Of North America 2006, 29: 471-486. PMID: 16650718, DOI: 10.1016/j.psc.2006.02.005.Peer-Reviewed Original ResearchConceptsSerotonin reuptake inhibitorsReuptake inhibitorsLong-term side effect profileFirst-choice treatmentFirst-line optionSide effect profileCurrent treatment strategiesDorsolateral caudate nucleusPathophysiology of OCDExpression of TSTypical antipsychoticsAtypical antipsychoticsClinical manifestationsSomato-sensoryGenetic epidemiologic studiesGlobus pallidusTreatment strategiesEpidemiologic studiesCaudate nucleusTourette syndromePatient associationsRelated disordersBehavioral therapyPresence of TsSegregation analysis studies