2024
F18. ROLE OF PSYCHIATRIC-ASSOCIATED SNVS IN THE EARLY ADULTHOOD: INSIGHTS FROM LONGITUDINAL NEUROIMAGING
Ito L, Ota V, Fernandes D, Martins A, Carvalho C, Zugman A, Sato J, Bressan R, Miguel E, Pan P, Salum G, Belangero S, Santoro M. F18. ROLE OF PSYCHIATRIC-ASSOCIATED SNVS IN THE EARLY ADULTHOOD: INSIGHTS FROM LONGITUDINAL NEUROIMAGING. European Neuropsychopharmacology 2024, 87: 214-215. DOI: 10.1016/j.euroneuro.2024.08.429.Peer-Reviewed Original ResearchPost-traumatic stress disorderAttention deficit/hyperactivity disorderBrain regionsBipolar disorderMental conditionBrain structuresBrazilian High-Risk Cohort StudyPrefrontal cortex regionsFrontal pole regionsHigh Risk Cohort StudyLateral orbitofrontal regionGenome-wide association studiesSignificant main effectDepressive disorderMixed-effects modelsStress disorderDeficit/hyperactivity disorderFrontal cortexOrbitofrontal regionsBiological underpinningsGenetic influencesCortex regionsLongitudinal relationshipIntracranial volumeEarly adulthood
2021
The impact of generalized anxiety disorder in obsessive-compulsive disorder patients.
Sharma P, Rosário M, Ferrão Y, Albertella L, Miguel E, Fontenelle L. The impact of generalized anxiety disorder in obsessive-compulsive disorder patients. Psychiatry Research 2021, 300: 113898. PMID: 33812219, DOI: 10.1016/j.psychres.2021.113898.Peer-Reviewed Original ResearchConceptsGeneralized anxiety disorderObsessive-compulsive disorderComorbid generalized anxiety disorderAnxiety disordersOnset of OCDType II bipolar disorderDiagnosis of GADTreatment of OCDObsessive-compulsive disorder patientsSevere anxiety symptomsMann-Whitney U testChi-square testPrevalent comorbiditiesClinical profileClinical severityMood disordersDisorder patientsComorbid anxietyPanic disorderBipolar disorderAvoidant behaviorComorbiditiesGreater suicidalityLogistic regressionU test
2011
Brazilian psychiatric brain bank: a new contribution tool to network studies
de Oliveira K, Nery F, Ferreti R, Lima M, Cappi C, Machado-Lima A, Polichiso L, Carreira L, Ávila C, Alho A, Brentani H, Miguel E, Heinsen H, Jacob-Filho W, Pasqualucci C, Lafer B, Grinberg L. Brazilian psychiatric brain bank: a new contribution tool to network studies. Cell And Tissue Banking 2011, 13: 315-326. PMID: 21562728, DOI: 10.1007/s10561-011-9258-0.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderBipolar disorderBrain BankBrazilian Aging Brain Study GroupMajor depressive disorderSubstance use disordersMood disorder NOSDepressive disorderStudy groupPsychiatric assessmentDisorder NOSUse disordersAverage ageAutopsy serviceNeuropsychiatric diseasesObsessive-compulsive spectrum symptomsOCD patientsOptimal fixationDisordersCompulsive disorderSpectrum symptomsBrainPsychiatric researchMolecular studiesUrgent need
2010
Bipolar disorder and comorbid obsessive‐compulsive disorder is associated with higher rates of anxiety and impulse control disorders
Issler C, Monkul E, Amaral J, Tamada R, Shavitt R, Miguel E, Lafer B. Bipolar disorder and comorbid obsessive‐compulsive disorder is associated with higher rates of anxiety and impulse control disorders. Acta Neuropsychiatrica 2010, 22: 81-86. PMID: 25385033, DOI: 10.1111/j.1601-5215.2010.00457.x.Peer-Reviewed Original ResearchTreatment-emergent maniaObsessive-compulsive disorderFemale BD patientsComorbid obsessive-compulsive disorderBipolar disorderControl disordersResidual symptomsDepressive episodeBD patientsOCD patientsPrevious depressive episodesStructured Clinical InterviewHigh rateClinical characteristicsDisorder burdenChronic episodesFemale outpatientsTic disordersHigh riskComorbid disordersSevere formPatientsClinical InterviewSkin pickingDSM-IV
2005
Clinical expression of obsessive-compulsive disorder in women with bipolar disorder
Issler C, de Mello Siqueira Amaral J, Tamada R, Schwartzmann A, Shavitt R, Miguel E, Lafer B. Clinical expression of obsessive-compulsive disorder in women with bipolar disorder. Brazilian Journal Of Psychiatry 2005, 27: 139-142. PMID: 15962140, DOI: 10.1590/s1516-44462005000200013.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderBipolar disorderRating ScaleObsessive-compulsive symptomsEarly onsetHamilton Depression Rating ScaleYoung Mania Rating ScaleNon-controlled designComorbid bipolar disorderSensory phenomenaDepression Rating ScaleStructured Clinical InterviewSeverity of symptomsMania Rating ScaleBipolar disorder ICompulsive Rating ScaleYale-Brown ObsessiveChronic motorManic episodesTic disordersVocal ticsClinical expressionClinical InterviewPsychopathological featuresDisorder I
2004
Transtorno de déficit de atenção/hiperatividade na infância e na adolescência: considerações clínicas e terapêuticas
Rohde L, Filho E, Benetti L, Gallois C, Kieling C. Transtorno de déficit de atenção/hiperatividade na infância e na adolescência: considerações clínicas e terapêuticas. Archives Of Clinical Psychiatry 2004, 31: 124-131. DOI: 10.1590/s0101-60832004000300002.Peer-Reviewed Original ResearchBipolar disorderAttention-deficit/hyperactivity disorderNon-systematic reviewPharmacological managementTherapeutic dilemmaDifferential diagnosisPrevalent disorderComorbid disordersClinical relevancePrecise diagnosisClinical tipsHyperactivity disorderDisordersClinical psychiatristsImpairment criteriaDiagnosisImportant impairmentComorbiditiesTreatmentAdequate useMedicationsReviewImpairment