2020
An Ixodes scapularis Protein Disulfide Isomerase Contributes to Borrelia burgdorferi Colonization of the Vector
Cao Y, Rosen C, Arora G, Gupta A, Booth CJ, Murfin KE, Cerny J, Lopez A, Chuang YM, Tang X, Pal U, Ring A, Narasimhan S, Fikrig E. An Ixodes scapularis Protein Disulfide Isomerase Contributes to Borrelia burgdorferi Colonization of the Vector. Infection And Immunity 2020, 88: 10.1128/iai.00426-20. PMID: 32928964, PMCID: PMC7671890, DOI: 10.1128/iai.00426-20.Peer-Reviewed Original ResearchConceptsTick gutTick bite siteVector-host interfaceAbility of spirochetesProtein disulfide isomerase A3Infected vertebrate hostsInflammatory responseBite siteLyme diseaseVertebrate hostsGutTick proteinsAdditional targetsMiceSpirochete life cycleSpirochete survivalArthropod vectorsSpirochetesRNA interferenceIllnessTicks
2007
Identification of Salp15 Homologues in Ixodes ricinus Ticks
Hovius JW, Ramamoorthi N, Veer C, de Groot KA, Nijhof AM, Jongejan F, van Dam AP, Fikrig E. Identification of Salp15 Homologues in Ixodes ricinus Ticks. Vector-Borne And Zoonotic Diseases 2007, 7: 296-303. PMID: 17896872, DOI: 10.1089/vbz.2006.0624.Peer-Reviewed Original ResearchConceptsSalp15 homologuesI. scapularis Salp15T cell activationDifferent Ixodes speciesAmino acid sequenceEntire amino acid sequenceSignal sequenceMammalian hostsProtein sequencesAcid sequenceC-terminusReverse transcriptase-polymerase chain reactionSensu strictoIxodes speciesSensu latoMajor vectorHomologuesB. burgdorferi sensu latoBorrelia speciesProteinSalp15Borrelia burgdorferi sensu strictoSpeciesI. ricinusBurgdorferi sensu stricto