1997
Protective and Arthritis-Resolving Activity in Sera of Mice Infected with Borrelia burgdorferi
Barthold S, Feng S, Bockenstedt L, Fikrig E, Feen K. Protective and Arthritis-Resolving Activity in Sera of Mice Infected with Borrelia burgdorferi. Clinical Infectious Diseases 1997, 25: s9-s17. PMID: 9233658, DOI: 10.1086/516166.Peer-Reviewed Original ResearchConceptsImmune serumSyringe challengePassive protective activitySerum of miceArthritis resolutionHost-adapted spirochetesImmunocompetent miceJoint tissuesTissue transplantsProtective activityImmunodominant regionMiceSerumInfectionBorrelia burgdorferiB. burgdorferiRecombinant formBurgdorferiSpirochetesTissueChallenge inoculationCarditisTransplantSpirochetemiaAntigen
1994
Partial destruction of Borrelia burgdorferi within ticks that engorged on OspE- or OspF-immunized mice
Nguyen TP, Lam TT, Barthold SW, Telford SR, Flavell RA, Fikrig E. Partial destruction of Borrelia burgdorferi within ticks that engorged on OspE- or OspF-immunized mice. Infection And Immunity 1994, 62: 2079-2084. PMID: 8168973, PMCID: PMC186469, DOI: 10.1128/iai.62.5.2079-2084.1994.Peer-Reviewed Original ResearchConceptsEarly-stage disease patientsMajority of patientsLate-stage diseaseSerum of miceLyme disease vaccineB. burgdorferiB. burgdorferi organismsExamination of seraNumber of spirochetesOuter surface protein ESyringe challengeDisease patientsImmune responseDisease vaccinePatientsHigh titersLyme diseaseMiceAntibodiesDiseaseSerumBurgdorferiBorreliaDaysProtein E