A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
Schleicher TR, Yang J, Freudzon M, Rembisz A, Craft S, Hamilton M, Graham M, Mlambo G, Tripathi AK, Li Y, Cresswell P, Sinnis P, Dimopoulos G, Fikrig E. A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission. Nature Communications 2018, 9: 2908. PMID: 30046053, PMCID: PMC6060088, DOI: 10.1038/s41467-018-05374-3.Peer-Reviewed Original ResearchConceptsSalivary gland proteinsCell traversal activityMosquito salivary gland proteinsMosquito salivaGland proteinsCell traversalInfected Anopheles mosquitoesThiol reductaseSporozoite movementVector proteinProteinPlasmodium parasitesAnopheles mosquitoesInitial infectionParasitesHost dermisVector salivaMass spectrometrySporozoitesSalivaMalariaLiverReductaseKey stepHost