Infectivity of Borrelia burgdorferi sensu lato is unaltered in C3-deficient mice
van Burgel ND, Balmus NC, Fikrig E, van Dam AP. Infectivity of Borrelia burgdorferi sensu lato is unaltered in C3-deficient mice. Ticks And Tick-borne Diseases 2010, 2: 20-26. PMID: 21771533, DOI: 10.1016/j.ttbdis.2010.10.003.Peer-Reviewed Original ResearchConceptsWT miceAbsence of C3B. burgdorferiB. afzeliiQuantitative PCRDifferent Borrelia speciesC3 knockout miceC3-deficient miceComplement-deficient miceWild-type miceB. afzelii infectionBorrelia burgdorferi sensu latoHuman complementInflammation scoreBurgdorferi sensu latoB. bavariensisAfzelii infectionBorrelia speciesKnockout miceMiceHeart tissueWeeksB. gariniiBurgdorferiSignificant differences