Roles of OspA, OspB, and flagellin in protective immunity to Lyme borreliosis in laboratory mice
Fikrig E, Barthold SW, Marcantonio N, Deponte K, Kantor FS, Flavell RA. Roles of OspA, OspB, and flagellin in protective immunity to Lyme borreliosis in laboratory mice. Infection And Immunity 1992, 60: 657-661. PMID: 1730500, PMCID: PMC257680, DOI: 10.1128/iai.60.2.657-661.1992.Peer-Reviewed Original ResearchConceptsProtective immunityProtective effectRecombinant outer surface protein AActive immunization experimentsSurface protein AOuter surface protein AB. burgdorferi proteinsActive immunizationResidual seraRecombinant OspAImmunization experimentsLyme borreliosisInfectionLyme disease agentMiceImmunityBorrelia burgdorferiAntibodiesImmunizationOspAOspBLaboratory miceSerumFlagellinDisease agents