2024
A nomogram combining neutrophil to lymphocyte ratio (NLR) and prognostic nutritional index (PNI) to predict distant metastasis in gastric cancer
Liu J, Sun R, Cai K, Xu Y, Yuan W. A nomogram combining neutrophil to lymphocyte ratio (NLR) and prognostic nutritional index (PNI) to predict distant metastasis in gastric cancer. Scientific Reports 2024, 14: 15391. PMID: 38965325, PMCID: PMC11224267, DOI: 10.1038/s41598-024-65307-7.Peer-Reviewed Original ResearchConceptsNeutrophil-to-lymphocyte ratioPrognostic nutritional indexPlatelet-to-lymphocyte ratioSystemic immune-inflammatory indexLymphocyte to monocyte ratioMultivariate logistic regression analysisDistant metastasisLogistic regression analysisLymphocyte ratioReceiver operating characteristicGastric cancerValidation cohortPredictive factorsRisk factors of distant metastasisDistant metastasis of gastric cancerNutritional indexImmune-inflammatory indexClinical practiceNomogram's predictive performanceDecision curve analysisGastric cancer patientsMetastasis of gastric cancerEfficient nomogramRegression analysisMonocyte ratioHyperbaric oxygen therapy ameliorates intestinal and systematic inflammation by modulating dysbiosis of the gut microbiota in Crohn’s disease
Li Y, Sun R, Lai C, Liu K, Yang H, Peng Z, Xu D, Huang F, Tang K, Peng Y, Liu X. Hyperbaric oxygen therapy ameliorates intestinal and systematic inflammation by modulating dysbiosis of the gut microbiota in Crohn’s disease. Journal Of Translational Medicine 2024, 22: 518. PMID: 38816750, PMCID: PMC11137967, DOI: 10.1186/s12967-024-05317-1.Peer-Reviewed Original ResearchConceptsGut microbiotaFecal microbiota transplantationHyperbaric oxygen therapyDysbiosis of gut microbiotaComposition of gut microbiotaC-reactive proteinCrohn's Disease Activity IndexRegulating gut microbiotaHost physiological conditionAbundance of EscherichiaDisease activity indexCrohn's diseaseClostridium XIVaModulating dysbiosisGene sequencesSystematic inflammationMicrobial diversityOxygen therapyPatients treated with hyperbaric oxygen therapyMicrobiotaColitis mouse modelLevels of C-reactive proteinMicrobiota transplantationSerum C-reactive proteinEffect of hyperbaric oxygen therapy
2021
Lung microbiome alterations in NSCLC patients
Zheng L, Sun R, Zhu Y, Li Z, She X, Jian X, Yu F, Deng X, Sai B, Wang L, Zhou W, Wu M, Li G, Tang J, Jia W, Xiang J. Lung microbiome alterations in NSCLC patients. Scientific Reports 2021, 11: 11736. PMID: 34083661, PMCID: PMC8175694, DOI: 10.1038/s41598-021-91195-2.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerNon-small cell lung cancer patientsRare speciesOral taxaLung microbiotaDiverse array of microbesNon-cancer controlsLobectomy samplesArray of microbesGlobal microbial compositionAssociated with lung cancer progressionLung cancerLung microbiome compositionBronchoscopy samplesPseudomonas entomophilaMetagenomic sequencingBronchoalveolar lavageLactobacillus rossiaeBacteroides pyogenesMicrobiota dysbiosisMicrobial communitiesMicrobiome compositionPaenibacillus odoriferMicrobial compositionLung microbiota dysbiosis