2024
Metagenomic analysis of the intestinal microbiome reveals the potential mechanism involved in Bacillus amyloliquefaciens in treating schistosomiasis japonica in mice
Chen H, Huang S, Zhao Y, Sun R, Wang J, Yao S, Huang J, Yu Z. Metagenomic analysis of the intestinal microbiome reveals the potential mechanism involved in Bacillus amyloliquefaciens in treating schistosomiasis japonica in mice. Microbiology Spectrum 2024, 12: e03735-23. PMID: 38441977, PMCID: PMC10986500, DOI: 10.1128/spectrum.03735-23.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacillus amyloliquefaciensBacteriaGastrointestinal MicrobiomeMiceSchistosoma japonicumSchistosomiasis japonicaUreaseConceptsTaxonomic compositionGut microbiomeIntestinal microbiomeFunctional genesKEGG OrthologyMetagenomic analysisIntestinal microbiotaRegulatory mechanismsFunction of gut microbiomeComposition of gut microbiotaAbundance of functional genesMetagenomic sequencingGene functionGut microbiotaPotential regulatory mechanismSpecies levelIntervention of probioticsBacillus amyloliquefaciensMicrobiomeGenesMicrobiotaHost immune responseProbiotic interventionMetabolic reactionsSchistosoma japonicum</i>
2023
Bacillus amyloliquefaciens alleviates the pathological injuries in mice infected with Schistosoma japonicum by modulating intestinal microbiome
Chen H, Sun R, Wang J, Yao S, Batool S, Yu Z, Huang S, Huang J. Bacillus amyloliquefaciens alleviates the pathological injuries in mice infected with Schistosoma japonicum by modulating intestinal microbiome. Frontiers In Cellular And Infection Microbiology 2023, 13: 1172298. PMID: 37265494, PMCID: PMC10230073, DOI: 10.3389/fcimb.2023.1172298.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacillus amyloliquefaciensGastrointestinal MicrobiomeLiverLiver CirrhosisMammalsMiceRNA, Ribosomal, 16SSchistosoma japonicumConceptsIntestinal microbiomeAbundances of potential pathogenic bacteriaRecovery of diversityRRNA gene sequencesPotential pathogenic bacteriaPathological organ damageEscherichia-ShigellaGene sequencesInteraction networkMammalian hostsBacillus amyloliquefaciensPathogenic bacteriaMicrobiomeIntestinal microenvironmentEffective therapeutic agentSchistosoma japonicum