2022
Infection risk in a real-world cohort of patients treated with long-term B-cell depletion for autoimmune neurologic disease
Peters J, Longbrake E. Infection risk in a real-world cohort of patients treated with long-term B-cell depletion for autoimmune neurologic disease. Multiple Sclerosis And Related Disorders 2022, 68: 104400. PMID: 36544307, PMCID: PMC10075342, DOI: 10.1016/j.msard.2022.104400.Peer-Reviewed Original ResearchMeSH KeywordsAutoimmune Diseases of the Nervous SystemFemaleHumansInfectionsMultiple SclerosisRetrospective StudiesRituximabConceptsLong-term B-cell depletionB-cell depletionReal-world cohortSevere infectionsTotal infectionsSingle-center observational studyEffective disease-modifying therapiesInfectious adverse effectsFormer smoking statusRisk of hospitalizationAutoimmune neurologic diseasesAutoimmune neurologic disordersDisease-modifying therapiesYears of treatmentRate of infectionLong-term useImmunologic changesLaboratory abnormalitiesClinical factorsSmoking statusHigher BMIMultiple sclerosisSerious infectionsNeurologic disordersFemale gender
2021
Manifestations and impact of the COVID‐19 pandemic in neuroinflammatory diseases
Levin SN, Venkatesh S, Nelson KE, Li Y, Aguerre I, Zhu W, Masown K, Rimmer KT, Diaconu CI, Onomichi KB, Leavitt VM, Levine LL, Strauss‐Farber R, Vargas WS, Banwell B, Bar‐Or A, Berger JR, Goodman AD, Longbrake EE, Oh J, Weinstock‐Guttman B, Thakur KT, Edwards KR, Riley CS, Xia Z, De Jager PL, Collaborative M. Manifestations and impact of the COVID‐19 pandemic in neuroinflammatory diseases. Annals Of Clinical And Translational Neurology 2021, 8: 918-928. PMID: 33616290, PMCID: PMC8013889, DOI: 10.1002/acn3.51314.Peer-Reviewed Original ResearchMeSH KeywordsAdultAutoimmune Diseases of the Nervous SystemCohort StudiesCOVID-19FemaleHumansMaleMiddle AgedMultiple SclerosisNervous System DiseasesPandemicsProspective StudiesSelf ReportConceptsNeuroinflammatory disordersMultiple sclerosisCOVID-19Year-long prospective studyPotential risk factorsPatient reported experienceTesting shortagesNeurological disabilityLiver diseaseNeuroinflammatory diseasesTelemedicine visitsProspective studyPotential confoundersMS casesRisk factorsNeurological careSevere casesTreatment changesSymptom criteriaEarly changesMore depressionReference groupCase prevalenceDisease managementGreater likelihood