2024
Association Between High-Sensitivity Troponin (hs-cTnT) and Diagnosis of Myocarditis in Previously Healthy Pediatric Patients
Degen M, Leviter J, Bradley A, Karnik R, Ferdman D, McCollum S, Faherty E. Association Between High-Sensitivity Troponin (hs-cTnT) and Diagnosis of Myocarditis in Previously Healthy Pediatric Patients. Pediatric Cardiology 2024, 1-7. PMID: 39126513, DOI: 10.1007/s00246-024-03621-7.Peer-Reviewed Original ResearchDiagnosis of myocarditisPediatric patientsHs-cTnTTroponin levelsCardiac diagnosisHigh-sensitivity troponin THealthy pediatric patientsHigh-sensitivity troponinHs-cTnT groupMedian peak levelSensitivity troponin levelsElevated hs-cTnTCut-off valueInitial troponin levelMyocarditis diagnosisAcute myocarditisTroponin valuesCardiac troponinPediatric populationTroponin TMyocarditisPatientsPeak levelsDiagnosisMyocardial tissueAcquired Heart Disease: Infective Endocarditis
Faherty, E, Murray T. Acquried Heart Disease: Infective Endocarditis. In Kliegman R, St. Game III J, editors. Nelson Textbook of Pediatrics, 22nd Edition.Chapters
2023
Combined Repair of Coarctation of the Aorta and Long-Segment Tracheal Stenosis in a Neonate
Lee M, Maurrasse S, Boules H, Faherty E, Weinstock M, Caty M. Combined Repair of Coarctation of the Aorta and Long-Segment Tracheal Stenosis in a Neonate. Annals Of Thoracic Surgery Short Reports 2023, 1: 666-669. DOI: 10.1016/j.atssr.2023.06.015.Peer-Reviewed Original ResearchTracheal stenosisLong-segment tracheal stenosisThorough airway evaluationSevere tracheal stenosisPulmonary artery slingSuccessful surgical treatmentComplete tracheal ringsDetailed preoperative planningAirway evaluationCoarctation repairAirway diseaseSurgical treatmentAirway repairRare entityCombined repairIncidental discoveryCongenital cardiacNewborn casesMultidisciplinary coordinationTracheal ringsPreoperative planningCoarctationStenosisAnesthesia specialtyAortaLongitudinal Assessment of Left Ventricular Function in Patients with Myopericarditis After mRNA COVID-19 Vaccination
NV B, McCollum S, Faherty E, Steele J, Karnik R. Longitudinal Assessment of Left Ventricular Function in Patients with Myopericarditis After mRNA COVID-19 Vaccination. Pediatric Cardiology 2023, 45: 1524-1532. PMID: 37294336, PMCID: PMC10251331, DOI: 10.1007/s00246-023-03200-2.Peer-Reviewed Original ResearchLeft ventricular longitudinal strainMRNA COVID-19 vaccinationCOVID-19 vaccinationSubclinical myocardial injuryEjection fractionFractional shorteningInitial presentationMyocardial injurySingle-center reviewMedian ejection fractionLeft ventricular functionVentricular longitudinal strainTime 0Area-length methodWilcoxon signed-rank testAcute illnessDiastolic functionVentricular functionDiastolic parametersLV functionRisk stratificationMyocardial recoveryTissue DopplerSigned-rank testMyopericarditis
2022
Coronavirus disease 2019 and the young heart: prevention, treatment, and return to play
Beach CM, Faherty E, Pesce M. Coronavirus disease 2019 and the young heart: prevention, treatment, and return to play. Current Opinion In Pediatrics 2022, 34: 471-475. PMID: 36036422, PMCID: PMC9593324, DOI: 10.1097/mop.0000000000001167.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCOVID-19 vaccinationRisk factorsSevere diseasePhysical activitySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissionAcute COVID-19 infectionAcute COVID-19Regular physical activityViral prevalenceCOVID-19 infectionSpecific risk factorsCoronavirus disease 2019Current care modelsPrevention of diseaseInflammatory syndromeCardiac manifestationsPoor outcomeDisease 2019Care modelYoung heartsViral transmissionInfectionDiseaseCOVID-19VaccinationShort-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination
Pareek M, Steele J, Asnes J, Baldassarre L, Casale L, Desai N, Elder R, Faherty E, Ferguson I, Fishman R, Ghazizadeh Z, Glick L, Hall E, Khera R, Kokkinidis D, Kwan J, O'Marr J, Schussheim A, Tuohy E, Wang Y, Spatz E, Jacoby D, Miller E. Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination. JACC Cardiovascular Imaging 2022, 15: 2002-2005. PMID: 36357140, PMCID: PMC9094612, DOI: 10.1016/j.jcmg.2022.03.026.Peer-Reviewed Case Reports and Technical NotesLongitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C)
He M, Leone DM, Frye R, Ferdman DJ, Shabanova V, Kosiv KA, Sugeng L, Faherty E, Karnik R. Longitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C). Pediatric Cardiology 2022, 43: 844-854. PMID: 34993558, PMCID: PMC8739007, DOI: 10.1007/s00246-021-02796-7.Peer-Reviewed Original ResearchConceptsMIS-C patientsAcute phaseChronic phaseInflammatory syndromeTwo-dimensional speckle tracking echocardiographySubclinical myocardial injuryCircumferential strainMultisystem inflammatory syndromeLeft ventricular dysfunctionSingle-institution reviewSpeckle tracking echocardiographyTwo-dimensional echocardiographyCoronavirus disease 2019Future adverse eventsVentricular function parametersBasal anterolateral segmentMean GCSVentricular dysfunctionAdverse eventsFractional shorteningSignificant sequelaeVentricular strainMyocardial dysfunctionGlobal longitudinalMyocardial injuryCorrelation of transthoracic echocardiography-derived pulmonary to systemic flow ratio with hemodynamically estimated left to right shunt in atrial septal defects.
Faherty E, Rajagopal H, Lee S, Love B, Srivastava S, Parness IA, Uppu SC. Correlation of transthoracic echocardiography-derived pulmonary to systemic flow ratio with hemodynamically estimated left to right shunt in atrial septal defects. Ann Pediatr Cardiol 2022, 15: 20-26. PMID: 35847407, DOI: 10.4103/apc.apc_139_21.Peer-Reviewed Original Research
2021
Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID‐19 and MIS‐C
Shah HP, Frye R, Chang S, Faherty E, Steele J, Karnik R. Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID‐19 and MIS‐C. Case Reports In Pediatrics 2021, 2021: 4797498. PMID: 34616578, PMCID: PMC8490073, DOI: 10.1155/2021/4797498.Peer-Reviewed Case Reports and Technical NotesPediatric myocarditisElevated inflammatory markersMultisystem inflammatory syndromeShortness of breathDiagnosis of myocarditisSudden cardiac deathCOVID-19Electrocardiogram findingsInflammatory markersInflammatory syndromeChest tightnessCardiac deathMale presentingAnnual incidenceClinical presentationD-dimerViral myocarditisMyocardial injuryClinical conundrumSubclinical presentationMyocarditisRare diseaseClinical experienceTrue prevalenceCurrent Covid-19 pandemic eraSymptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination
Marshall M, Ferguson ID, Lewis P, Jaggi P, Gagliardo C, Collins JS, Shaughnessy R, Caron R, Fuss C, Corbin KJE, Emuren L, Faherty E, Hall EK, Di Pentima C, Oster ME, Paintsil E, Siddiqui S, Timchak DM, Guzman-Cottrill JA. Symptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination. Pediatrics 2021, 148: e2021052478. PMID: 34088762, DOI: 10.1542/peds.2021-052478.Peer-Reviewed Original ResearchConceptsPfizer-BioNTech COVID-19 vaccinationCOVID-19 vaccinationAcute myocarditisClinical courseLate gadolinium enhancement (LGE) characteristicsPolymerase chain reaction test resultsTranscription polymerase chain reaction (RT-PCR) test resultsVaccine Adverse Event Reporting SystemCoronavirus disease 2019 (COVID-19) vaccinationAcute COVID-19Multisystem inflammatory syndromeAdverse Event Reporting SystemImportant adverse eventsTime of presentationNonsteroidal antiinflammatory drugsHealthy male adolescentsGadolinium enhancement characteristicsEvent Reporting SystemReaction test resultsChest painElevated troponinInflammatory syndromeIntravenous immunoglobulinAdverse eventsSecond dose