2011
P4-11-10: Perceptions, Knowledge and Satisfaction with Contralateral Prophylactic Mastectomy among Young Women with Breast Cancer.
Tracy M, Meyer M, Sepucha K, Gelber S, Hirshfield-Bartek J, Troyan S, Morrow M, Schapira L, Come S, Winer E, Partridge A. P4-11-10: Perceptions, Knowledge and Satisfaction with Contralateral Prophylactic Mastectomy among Young Women with Breast Cancer. Cancer Research 2011, 71: p4-11-10-p4-11-10. DOI: 10.1158/0008-5472.sabcs11-p4-11-10.Peer-Reviewed Original ResearchContralateral prophylactic mastectomyContralateral breast cancerBreast cancerBilateral mastectomyYoung womenProphylactic mastectomyBenefits of CPMEarly breast cancerBilateral breast cancerSurgical treatment decisionsLongitudinal cohort studyBreast cancer treatmentPercent of womenCohort studyContralateral diseaseMedian ageProphylactic indicationsPatient preferencesTreatment decisionsMutation carriersAge 40MastectomyCancerCancer ResCancer treatment
2009
Prevalence and Predictors of Distress in Young Women with Newly Diagnosed Early Stage Breast Cancer.
Ruddy K, Gelber S, Tamimi R, Mayer E, Schapira L, Come S, Meyer M, Winer E, Partridge A. Prevalence and Predictors of Distress in Young Women with Newly Diagnosed Early Stage Breast Cancer. Cancer Research 2009, 69: 1067-1067. DOI: 10.1158/0008-5472.sabcs-09-1067.Peer-Reviewed Original ResearchStage breast cancerBreast cancerOverall distressYoung womenHADS scoresProspective multi-center cohort studyAdvanced-stage breast cancerMulti-center cohort studyEarly-stage breast cancerMultivariate logistic regression modelBaseline surveyOnly sociodemographic factorCentral pathology reviewEarly breast cancerMultivariate logistic regressionPercent of womenCourse of careMedical history itemsLogistic regression modelsBreast cancer diagnosisEligible womenCohort studyMedian agePathology reviewHospital Anxiety
2007
Phase II study of CT-2103 as first- or second-line chemotherapy in patients with metastatic breast cancer: unexpected incidence of hypersensitivity reactions
Lin NU, Parker LM, Come SE, Burstein HJ, Haldoupis M, Ryabin N, Gelman R, Winer EP, Shulman LN. Phase II study of CT-2103 as first- or second-line chemotherapy in patients with metastatic breast cancer: unexpected incidence of hypersensitivity reactions. Investigational New Drugs 2007, 25: 369-375. PMID: 17345004, DOI: 10.1007/s10637-007-9034-y.Peer-Reviewed Original ResearchConceptsMetastatic breast cancerHypersensitivity reactionsEfficacy of CTBreast cancerPrior linesPatient populationGrade 3HER2-negative metastatic breast cancerSmall studyHER2-negative breast cancerTrue drug allergyPhase II studySecond-line chemotherapyPercent of womenNovel conjugatesAdjuvant settingConjugated paclitaxelEighteen womenIntravenous CTMetastatic treatmentPrior chemotherapyRoutine premedicationDrug allergyII studyObjective response
2005
The association of ambulatory care with breast cancer stage at diagnosis among medicare beneficiaries
Keating NL, Landrum MB, Ayanian JZ, Winer EP, Guadagnoli E. The association of ambulatory care with breast cancer stage at diagnosis among medicare beneficiaries. Journal Of General Internal Medicine 2005, 20: 38-44. PMID: 15693926, PMCID: PMC1490029, DOI: 10.1111/j.1525-1497.2004.40079.x.Peer-Reviewed Original ResearchConceptsPrimary care physiciansCare physiciansBreast cancer diagnosisAdvanced cancerOutpatient careNumber of visitsMedical specialistsAdvanced stage diagnosisPreventive care visitsRetrospective cohort studyCancer diagnosisBreast cancer stagePercent of womenPopulation-based sampleCare visitsCohort studyCancer RegistryCancer stageUse of servicesElderly womenAdjusted ratesBreast cancerLower median incomeAmbulatory careHigh risk
2004
Web-Based Survey of Fertility Issues in Young Women With Breast Cancer
Partridge AH, Gelber S, Peppercorn J, Sampson E, Knudsen K, Laufer M, Rosenberg R, Przypyszny M, Rein A, Winer EP. Web-Based Survey of Fertility Issues in Young Women With Breast Cancer. Journal Of Clinical Oncology 2004, 22: 4174-4183. PMID: 15483028, DOI: 10.1200/jco.2004.01.159.Peer-Reviewed Original ResearchConceptsPercent of womenBreast cancerYoung womenFertility issuesEarly-stage breast cancerYoung breast cancer survivorsYear of diagnosisBreast cancer survivorsMultivariate logistic regressionE-mail remindersBreast cancer diagnosisPrior pregnancyYounger patientsCancer survivorsFertility concernsTreatment decisionsWeb-based surveyEligible respondentsInfertility concernsLogistic regressionCancerDiagnosisCancer diagnosisWomenMore children
2003
Consultation with a medical oncologist before surgery and type of surgery among elderly women with early-stage breast cancer.
Keating NL, Landrum MB, Ayanian JZ, Winer EP, Guadagnoli E. Consultation with a medical oncologist before surgery and type of surgery among elderly women with early-stage breast cancer. Journal Of Clinical Oncology 2003, 21: 4532-9. PMID: 14673040, DOI: 10.1200/jco.2003.05.131.Peer-Reviewed Original ResearchConceptsBreast-conserving surgeryDefinitive surgeryMedical oncologistsType of surgeryElderly womenAxillary dissectionBreast cancerEarly-stage breast cancerGuideline-recommended careRetrospective cohort studyAxillary node dissectionBreast cancer treatmentPercent of womenPopulation-based sampleComorbid illnessesNode dissectionCohort studyGuideline recommendationsDifferentiated cancerTeaching hospitalAdjusted proportionSurgeryOncologistsCancer treatmentWomen
2001
Clinical activity of trastuzumab and vinorelbine in women with HER2-overexpressing metastatic breast cancer.
Burstein H, Kuter I, Campos S, Gelman R, Tribou L, Parker L, Manola J, Younger J, Matulonis U, Bunnell C, Partridge A, Richardson P, Clarke K, Shulman L, Winer E. Clinical activity of trastuzumab and vinorelbine in women with HER2-overexpressing metastatic breast cancer. Journal Of Clinical Oncology 2001, 19: 2722-30. PMID: 11352965, DOI: 10.1200/jco.2001.19.10.2722.Peer-Reviewed Original ResearchConceptsGrade 2 cardiac toxicityAdvanced breast cancerBreast cancerResponse rateCardiac toxicityHER2-overexpressing metastatic breast cancerOnly grade 4 toxicityHER2-positive breast cancerCumulative doxorubicin doseGrade 4 toxicityStudy of trastuzumabSymptomatic heart failureThird-line therapyFirst-line therapyType of chemotherapyMetastatic breast cancerPercent of womenHigh response rateConcurrent trastuzumabPrior chemotherapyWeekly vinorelbineMetastatic diseasePositive patientsHeart failureDoxorubicin dose
1999
Attitudes, knowledge, and risk perceptions of women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2.
Bluman L, Rimer B, Berry D, Borstelmann N, Iglehart J, Regan K, Schildkraut J, Winer E. Attitudes, knowledge, and risk perceptions of women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2. Journal Of Clinical Oncology 1999, 17: 1040-6. PMID: 10071299, DOI: 10.1200/jco.1999.17.3.1040.Peer-Reviewed Original ResearchConceptsOvarian cancerBRCA2 mutationsHigh-risk womenPercent of womenBaseline questionnairePhysician referralCancer riskChallenges cliniciansGenetic testingKnowledge deficitsWomenCancerGene mutationsBreastBRCA2PatientsBaseline knowledgeRiskBRCA1Cancer geneticsTrialsRisk perceptionHigher proportionMutationsPerception of risk