2013
Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey.
Rosenberg SM, Tracy MS, Meyer ME, Sepucha K, Gelber S, Hirshfield-Bartek J, Troyan S, Morrow M, Schapira L, Come SE, Winer EP, Partridge AH. Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey. Annals Of Internal Medicine 2013, 159: 373-81. PMID: 24042365, PMCID: PMC3968260, DOI: 10.7326/0003-4819-159-6-201309170-00003.Peer-Reviewed Original ResearchConceptsContralateral prophylactic mastectomyContralateral breast cancerBreast cancerCross-sectional surveyYoung womenProphylactic mastectomyBilateral breast cancerBreast cancer worryAge 40 yearsCommunity medical centerBRCA2 mutation carriersSusan G. KomenBilateral mastectomyUnaffected breastCancer worryMedical CenterMutation carriersMost womenCancerEvidence-based decisionsMastectomyRecall biasWomenRiskActual riskNeoadjuvant bevacizumab: surgical complications of mastectomy with and without reconstruction
Kansal KJ, Dominici LS, Tolaney SM, Isakoff SJ, Smith BL, Jiang W, Brock JE, Winer EP, Krop IE, Golshan M. Neoadjuvant bevacizumab: surgical complications of mastectomy with and without reconstruction. Breast Cancer Research And Treatment 2013, 141: 255-259. PMID: 24026859, DOI: 10.1007/s10549-013-2682-z.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsBevacizumabBreast NeoplasmsFemaleHumansMammaplastyMastectomyMiddle AgedNeoadjuvant TherapyNeoplasm StagingPostoperative ComplicationsTreatment OutcomeYoung AdultConceptsSurgical complicationsAC/TPostoperative complicationsComplication rateCohort 2Cohort 1Breast cancerExact testImmediate expander/implant reconstructionHER2-negative breast cancerExpander/implant reconstructionOperable breast cancerOverall complication rateRate of complicationsThird of patientsCohort of patientsSame healthcare systemSingle-arm trialFisher's exact testUse of BevTerms of demographicsNeoadjuvant bevacizumabNeoadjuvant therapyImplant reconstructionMastectomyChoosing mastectomy over lumpectomy: Factors associated with surgical decisions in young women with breast cancer.
Rosenberg S, Sepucha K, Ruddy K, Tamimi R, Gelber S, Meyer M, Schapira L, Come S, Borges V, Winer E, Partridge A. Choosing mastectomy over lumpectomy: Factors associated with surgical decisions in young women with breast cancer. Journal Of Clinical Oncology 2013, 31: 6507-6507. DOI: 10.1200/jco.2013.31.15_suppl.6507.Peer-Reviewed Original ResearchBreast cancerYoung womenSurgical decisionStage IMulti-center cohort studyEstrogen receptor-positive tumorsReceptor-positive tumorsFinal multivariable modelFear of recurrenceDefinitive surgeryNodal involvementCohort studyMedian ageBilateral mastectomyER statusMultivariable analysisLower BMIPositive tumorsTumor sizeSurgical choiceOvarian cancerTumor gradeMultivariable modelMastectomyAge 40Psychosexual Functioning and Body Image Following a Diagnosis of Ductal Carcinoma In Situ
Bober SL, Giobbie‐Hurder A, Emmons KM, Winer E, Partridge A. Psychosexual Functioning and Body Image Following a Diagnosis of Ductal Carcinoma In Situ. The Journal Of Sexual Medicine 2013, 10: 370-377. PMID: 22812628, DOI: 10.1111/j.1743-6109.2012.02852.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Agents, HormonalArousalBody ImageBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingCohort StudiesCombined Modality TherapyDepressive DisorderFemaleFollow-Up StudiesHumansMassachusettsMastectomyMiddle AgedPersonal SatisfactionSexual BehaviorSurveys and QuestionnairesConceptsDiagnosis of DCISSexual functionHormonal therapyDuctal carcinomaPsychosexual functioningSexual functioningLarge-scale prospective studiesBody imageInvasive breast cancerProspective studyTreatment modalitiesTreatment optionsProspective surveySitu cancerBreast cancerDCISGeneral populationPsychosexual functionPatientsPsychosocial challengesDiagnosisTime pointsWomenMastectomySexual satisfaction
2012
Survival Implications Associated with Variation in Mastectomy Rates for Early‐Staged Breast Cancer
Brooks JM, Chrischilles EA, Landrum MB, Wright KB, Fang G, Winer EP, Keating NL. Survival Implications Associated with Variation in Mastectomy Rates for Early‐Staged Breast Cancer. International Journal Of Surgical Oncology 2012, 2012: 127854. PMID: 22928097, PMCID: PMC3423912, DOI: 10.1155/2012/127854.Peer-Reviewed Original ResearchEarly-stage breast cancerMastectomy ratesESBC patientsRCT populationBreast cancerSurvival implicationsHealth Consensus Development ConferenceHigher mastectomy ratesConsensus Development ConferenceSurgery choicePatientsMastectomyDevelopment ConferenceNIH guidelinesNational InstituteRecent evidenceRCTsCancerBreastSurvivalPatient alignmentGuidelinesSurgeryPopulation
2011
P4-11-10: Perceptions, Knowledge and Satisfaction with Contralateral Prophylactic Mastectomy among Young Women with Breast Cancer.
Tracy M, Meyer M, Sepucha K, Gelber S, Hirshfield-Bartek J, Troyan S, Morrow M, Schapira L, Come S, Winer E, Partridge A. P4-11-10: Perceptions, Knowledge and Satisfaction with Contralateral Prophylactic Mastectomy among Young Women with Breast Cancer. Cancer Research 2011, 71: p4-11-10-p4-11-10. DOI: 10.1158/0008-5472.sabcs11-p4-11-10.Peer-Reviewed Original ResearchContralateral prophylactic mastectomyContralateral breast cancerBreast cancerBilateral mastectomyYoung womenProphylactic mastectomyBenefits of CPMEarly breast cancerBilateral breast cancerSurgical treatment decisionsLongitudinal cohort studyBreast cancer treatmentPercent of womenCohort studyContralateral diseaseMedian ageProphylactic indicationsPatient preferencesTreatment decisionsMutation carriersAge 40MastectomyCancerCancer ResCancer treatment
2010
Outcomes following local therapy for early-stage breast cancer in non-trial populations
Keating NL, Landrum MB, Brooks JM, Chrischilles EA, Winer EP, Wright K, Volya R. Outcomes following local therapy for early-stage breast cancer in non-trial populations. Breast Cancer Research And Treatment 2010, 125: 803-813. PMID: 20376555, PMCID: PMC2924956, DOI: 10.1007/s10549-010-0865-4.Peer-Reviewed Original ResearchConceptsBreast-conserving surgeryEarly-stage breast cancerClinical trialsBreast cancerEarly-stage breast cancer patientsPrimary breast cancer therapyPrimary breast cancer treatmentEnd Results cancer registryNon-trial populationBreast cancer patientsPopulation-based dataBreast cancer treatmentBreast cancer therapyNon-selected populationPropensity score analysisMedicare administrative dataMore mastectomiesPrimary therapyLocal therapySurveillance EpidemiologyAdjusted survivalCancer RegistryCancer patientsHospital characteristicsMastectomy